1996
Ionic mechanisms underlying synchronized oscillations and propagating waves in a model of ferret thalamic slices
Destexhe A, Bal T, McCormick D, Sejnowski T. Ionic mechanisms underlying synchronized oscillations and propagating waves in a model of ferret thalamic slices. Journal Of Neurophysiology 1996, 76: 2049-2070. PMID: 8890314, DOI: 10.1152/jn.1996.76.3.2049.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAxonsBicucullineCalciumCalcium ChannelsElectrophysiologyFerretsGABA AntagonistsIn Vitro TechniquesIon ChannelsKineticsMembrane PotentialsModels, NeurologicalNeural Networks, ComputerPotassium ChannelsRecruitment, NeurophysiologicalRefractory Period, ElectrophysiologicalReticular FormationSynapsesThalamusUp-RegulationConceptsInhibitory postsynaptic potentialsExcitatory postsynaptic potentialsSlow inhibitory postsynaptic potentialFerret thalamic slicesActivity-dependent upregulationTC cellsRE cellsPostsynaptic potentialsThalamic slicesGABAergic inhibitory postsynaptic potentialsSpindle oscillationsCalcium-sensitive currentGABAB inhibitory postsynaptic potentialsLocal axonal arborizationsThalamic reticular neuronsGamma-aminobutyric acidRE neuronsGABAB receptorsIsoxazolepropionic acidRebound burstsReticular neuronsTC neuronsGABAA inhibitionAxonal arborizationBurst discharges
1989
GABA as an inhibitory neurotransmitter in human cerebral cortex
McCormick D. GABA as an inhibitory neurotransmitter in human cerebral cortex. Journal Of Neurophysiology 1989, 62: 1018-1027. PMID: 2573696, DOI: 10.1152/jn.1989.62.5.1018.Peer-Reviewed Original ResearchConceptsInhibitory postsynaptic potentialsGamma-aminobutyric acidEarly inhibitory postsynaptic potentialHuman cerebral cortexExcitatory postsynaptic potentialsAverage reversal potentialCerebral cortexInhibitory neurotransmitterPostsynaptic potentialsLate inhibitory postsynaptic potentialsSlow inhibitory postsynaptic potentialGABAergic inhibitory postsynaptic potentialsInitial excitatory postsynaptic potentialsReversal potentialGABAB agonist baclofenGABAB antagonist phaclofenGABAA antagonist bicucullineGABAA agonist muscimolParoxysmal epileptiform activityMajor inhibitory neurotransmitterVitro. 2Antagonist phaclofenMembrane conductanceAgonist baclofenAntagonist bicuculline