1993
Control of firing mode of corticotectal and corticopontine layer V burst-generating neurons by norepinephrine, acetylcholine, and 1S,3R- ACPD
Wang Z, McCormick D. Control of firing mode of corticotectal and corticopontine layer V burst-generating neurons by norepinephrine, acetylcholine, and 1S,3R- ACPD. Journal Of Neuroscience 1993, 13: 2199-2216. PMID: 8386756, PMCID: PMC6576582, DOI: 10.1523/jneurosci.13-05-02199.1993.Peer-Reviewed Original ResearchConceptsIntracellular recordingsMetabotropic receptorsPyramidal cellsLayer V pyramidal cellsGlutamate metabotropic receptor agonistLayer V cellsMetabotropic receptor agonistApplication of norepinephrineAlpha-agonist phenylephrineBeta-antagonist propranololSingle spike activityMuscarinic antagonist scopolamineBeta-agonist isoprenalinePrimary visual cortexAction potential generationSingle-spike modeACh effectsMuscarinic subtypesNE responseInterburst frequencyMuscarinic agonistsReceptor agonistBath applicationPostsynaptic responsesAntagonist scopolamine
1988
Noradrenergic modulation of firing pattern in guinea pig and cat thalamic neurons, in vitro
McCormick D, Prince D. Noradrenergic modulation of firing pattern in guinea pig and cat thalamic neurons, in vitro. Journal Of Neurophysiology 1988, 59: 978-996. PMID: 3367206, DOI: 10.1152/jn.1988.59.3.978.Peer-Reviewed Original ResearchConceptsSlow depolarizationElectrophysiological actionsPT neuronsGuinea pigsSlow membrane timeSpike frequency accommodationApplication of norepinephrineSingle spike activityMedial geniculate nucleusExtracellular potassium concentrationCat thalamic neuronsLarge afterhyperpolarizationSlow afterdepolarizationSlow afterhyperpolarizationAnteroventral nucleusCerebral cortexFrequency accommodationThalamic neuronsThalamocortical rhythmsThalamic nucleiGeniculate nucleusIntracellular recordingsNoradrenergic modulationSynaptic transmissionThalamic slices