2024
Patterns of loco-regional progression and patient outcomes after definitive-dose radiation therapy for anaplastic thyroid cancer
Bronk J, Augustyn A, Mohamed A, Fuller C, Garden A, Moreno A, Lee A, Morrison W, Phan J, Reddy J, Rosenthal D, Spiotto M, Frank S, Dadu R, Busaidy N, Zafereo M, Wang J, Maniakas A, Ferrarotto R, Iyer P, Cabanillas M, Gunn G. Patterns of loco-regional progression and patient outcomes after definitive-dose radiation therapy for anaplastic thyroid cancer. Radiotherapy And Oncology 2024, 202: 110602. PMID: 39489425, DOI: 10.1016/j.radonc.2024.110602.Peer-Reviewed Original ResearchIntensity modulated radiation therapyLoco-regional progressionAnaplastic thyroid cancerTarget volumeConcurrent chemotherapyRadiation therapyThyroid cancerHigh dosesAreas of gross diseaseMedian progression free survivalMedian IMRT doseGross tumor volumeMedian overall survivalProgression free survivalNeo-adjuvant strategiesDeformable image registrationIntensive treatment scheduleLevels II-VDiagnostic CTsIMRT dosePlanning CTsGross diseaseLocoregional diseaseUnresectable diseaseFree survival
2023
Patterns of failure for recurrent head and neck squamous cell carcinoma treated with salvage surgery and postoperative IMRT reirradiation
Mohamed A, Martin G, Ng S, Takiar V, Beadle B, Zafereo M, Garden A, Frank S, Fuller C, Gunn G, Morrison W, Rosenthal D, Reddy J, Moreno A, Lee A, Phan J. Patterns of failure for recurrent head and neck squamous cell carcinoma treated with salvage surgery and postoperative IMRT reirradiation. Clinical And Translational Radiation Oncology 2023, 44: 100700. PMID: 38058404, PMCID: PMC10695834, DOI: 10.1016/j.ctro.2023.100700.Peer-Reviewed Original ResearchLocoregional recurrenceSalvage surgeryRecurrent headNeck squamous cell cancerNeck squamous cell carcinomaPhysician's classificationMarginal failureSubsequent locoregional recurrenceSquamous cell cancerSquamous cell carcinomaPatterns of failureLogistic regression analysisDeformable image registrationAdjuvant reirradiationRadiological progressionSurgical salvageInitial recurrenceRecurrent diseaseSalvage rateRecurrent HNSCCCell cancerMucosal sitesCell carcinoma