2017
Nitrogen mustard-induced corneal injury involves the sphingomyelin-ceramide pathway
Charkoftaki G, Jester JV, Thompson DC, Vasiliou V. Nitrogen mustard-induced corneal injury involves the sphingomyelin-ceramide pathway. The Ocular Surface 2017, 16: 154-162. PMID: 29129753, PMCID: PMC7376578, DOI: 10.1016/j.jtos.2017.11.004.Peer-Reviewed Original ResearchConceptsCorneal damageNM exposureSphingomyelin-ceramide pathwayCorneal stromaIrreversible corneal damageNitrogen mustardAltered lipid profileSulfur mustardCorneal injuryLipid profileCentral corneaCorneal epitheliumRabbit eyesSpecific sphingomyelinsPotent vesicantCorneaOrgan cultureStromaLipidomic analysisExposureMorphological changesDamaging effectsDamageInjuryPathway
1990
Enzymatic Modulation of Vasoactive Intestinal Peptide and Nonadrenergic Noncholinergic Inhibitory Responses in Guinea Pig Tracheae
Thompson D, Diamond L, Altiere R. Enzymatic Modulation of Vasoactive Intestinal Peptide and Nonadrenergic Noncholinergic Inhibitory Responses in Guinea Pig Tracheae. American Journal Of Respiratory And Critical Care Medicine 1990, 142: 1119-1123. PMID: 2240834, DOI: 10.1164/ajrccm/142.5.1119.Peer-Reviewed Original ResearchConceptsVasoactive intestinal peptideNANC inhibitory responsesGuinea pig tracheaConcentration-response curvesInhibitory responsesIntestinal peptideInhibitory systemPig tracheaNonadrenergic noncholinergic inhibitory responsesVIP concentration-response curveExogenous vasoactive intestinal peptideRelaxation responseExogenous VIP administrationNANC inhibitory neurotransmitterNANC nerve stimulationNANC relaxation responsesNoncholinergic inhibitory responsesElectrical field stimulationSoybean trypsin inhibitorAdrenergic inhibitoryTachykinin depletionCholinergic excitatoryVIP administrationAutonomic nervesNerve stimulationNonadrenergic bronchodilation induced by high concentrations of sulfur dioxide
Thompson D, Szarek J, Altiere R, Diamond L. Nonadrenergic bronchodilation induced by high concentrations of sulfur dioxide. Journal Of Applied Physiology 1990, 69: 1786-1791. PMID: 2272972, DOI: 10.1152/jappl.1990.69.5.1786.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBronchoconstrictionBronchodilator AgentsCatsDose-Response Relationship, DrugFemaleLung ComplianceMaleOsmolar ConcentrationSulfur DioxideConceptsBronchodilator responseNonadrenergic noncholinergicGanglionic blocking agent hexamethoniumAirway smooth muscle toneConcentration-dependent bronchodilationNANC inhibitory transmitterDynamic lung complianceCyclooxygenase inhibitor indomethacinSmooth muscle toneAgent hexamethoniumBronchoconstrictive stimuliNonadrenergic bronchodilationBronchomotor toneIntravenous atropineAutonomic reflexesInhibitory transmitterLung complianceLung resistanceContinuous infusionFeline airwaysMuscle toneCromolyn sodiumInhibitor indomethacinInhibitory systemBronchodilationNICOTINIC AGONIST MODULATION OF FELINE BRONCHOMOTOR TONE
Thompson D, Altiere R, Diamond L. NICOTINIC AGONIST MODULATION OF FELINE BRONCHOMOTOR TONE. Clinical And Experimental Pharmacology And Physiology 1990, 17: 83-97. PMID: 2328544, DOI: 10.1111/j.1440-1681.1990.tb01291.x.Peer-Reviewed Original Research