1997
Absence of tachykinin involvement in leukotriene D4 and antigen-induced contraction of guinea pig isolated bronchus.
Cibulsky S, Thompson D. Absence of tachykinin involvement in leukotriene D4 and antigen-induced contraction of guinea pig isolated bronchus. Journal Of Pharmacology And Experimental Therapeutics 1997, 283: 1102-9. PMID: 9399982.Peer-Reviewed Original ResearchConceptsD4-induced contractionAntigen-induced contractionGuinea-pig bronchiLeukotriene D4Endogenous tachykininsPig bronchiNeutral endopeptidaseLeukotriene D4-induced contractionMast cell-derived mediatorsAirway smooth muscle cellsConcentration of tachykininOvalbumin-induced contractionGuinea pig airwaysCell-derived mediatorsPresence of tetrodotoxinNeurokinin receptor antagonistsAngiotensin-converting enzymeSmooth muscle cellsTachykinin involvementTachykininergic responsesContractile actionPig airwaysReceptor antagonistTetrodotoxin treatmentTachykinins
1992
Omega-conotoxin-sensitive calcium channels modulate autonomic neurotransmission in guinea pig airways.
Altiere R, Diamond L, Thompson D. Omega-conotoxin-sensitive calcium channels modulate autonomic neurotransmission in guinea pig airways. Journal Of Pharmacology And Experimental Therapeutics 1992, 260: 98-103. PMID: 1309883.Peer-Reviewed Original ResearchMeSH KeywordsAcetylcholineAnimalsAtropineAutonomic Nervous SystemBronchiCalcium ChannelsCapsaicinCholineElectric StimulationEpinephrineGuanethidineGuinea PigsIndomethacinMaleMuscle ContractionNeurons, AfferentNeurons, EfferentOmega-Conotoxin GVIAPeptides, CyclicPropranololSynaptic TransmissionTachykininsTracheaConceptsSensitive calcium channelsCalcium channelsCholinergic excitatoryNeuronal N-type voltage-sensitive calcium channelsN-type voltage-sensitive calcium channelsNonadrenergic noncholinergic (NANC) inhibitory nervesNonadrenergic noncholinergic inhibitory responsesVoltage-sensitive calcium channelsNoncholinergic inhibitory nervesNoncholinergic inhibitory responsesGuinea pig airwaysGuinea-pig bronchiElectrical field stimulationGuinea pig tracheaMarine snail Conus geographusConcentration-response relationshipAirway nervesAutonomic neurotransmissionTachykininergic responsesExogenous acetylcholineInhibitory nervesContractile responseConotoxin GVIAPig airwaysExcitatory responses