1998
Differential susceptibility of tracheal contraction to nonadrenergic noncholinergic relaxation.
Thompson D, Altiere R. Differential susceptibility of tracheal contraction to nonadrenergic noncholinergic relaxation. Journal Of Pharmacology And Experimental Therapeutics 1998, 284: 19-24. PMID: 9435155.Peer-Reviewed Original ResearchConceptsAirway smooth muscle contractionSmooth muscle contractionInduction of toneMuscle contractionNerve stimulationNitric oxide-dependent componentAirway smooth muscle toneNitric oxide synthase inhibitorOvalbumin-sensitized guinea pigsNerve-induced relaxationNonadrenergic noncholinergic relaxationElectrical field stimulationOxide synthase inhibitorSmooth muscle toneLevel of toneNoncholinergic relaxationTracheal contractionRelaxant responsesContractile actionAirway tissueNerve activationContractile agonistsMuscle toneField stimulationSynthase inhibitor
1997
Absence of tachykinin involvement in leukotriene D4 and antigen-induced contraction of guinea pig isolated bronchus.
Cibulsky S, Thompson D. Absence of tachykinin involvement in leukotriene D4 and antigen-induced contraction of guinea pig isolated bronchus. Journal Of Pharmacology And Experimental Therapeutics 1997, 283: 1102-9. PMID: 9399982.Peer-Reviewed Original ResearchConceptsD4-induced contractionAntigen-induced contractionGuinea-pig bronchiLeukotriene D4Endogenous tachykininsPig bronchiNeutral endopeptidaseLeukotriene D4-induced contractionMast cell-derived mediatorsAirway smooth muscle cellsConcentration of tachykininOvalbumin-induced contractionGuinea pig airwaysCell-derived mediatorsPresence of tetrodotoxinNeurokinin receptor antagonistsAngiotensin-converting enzymeSmooth muscle cellsTachykinin involvementTachykininergic responsesContractile actionPig airwaysReceptor antagonistTetrodotoxin treatmentTachykinins
1988
The effect of epithelium removal on non-adrenergic, non-cholinergic inhibitory responses in the isolated central airways of the cat and guinea pig
Thompson D, Wells J, Altiere R, Diamond L. The effect of epithelium removal on non-adrenergic, non-cholinergic inhibitory responses in the isolated central airways of the cat and guinea pig. European Journal Of Pharmacology 1988, 145: 231-237. PMID: 3350044, DOI: 10.1016/0014-2999(88)90237-3.Peer-Reviewed Original ResearchConceptsElectrical field stimulationEpithelium removalField stimulationHilar bronchusNon-cholinergic inhibitory responsesTissue sensitivityRelaxation responseNANC relaxation responsesGuinea pig tracheaBronchial sensitivityAirway preparationsContractile responseContractile actionContractile agonistsCentral airwaysPig tracheaAirway epitheliumInhibitory responsesPharmacological agonistsFeline tracheaGuinea pigsBronchusStimulationAgonistsTrachea