2020
Identification of a brain fingerprint for overweight and obesity
Farruggia MC, van Kooten MJ, Perszyk EE, Burke MV, Scheinost D, Constable RT, Small DM. Identification of a brain fingerprint for overweight and obesity. Physiology & Behavior 2020, 222: 112940. PMID: 32417645, PMCID: PMC7321926, DOI: 10.1016/j.physbeh.2020.112940.Peer-Reviewed Original ResearchConceptsPercent body fatWaist circumferenceBody fatWhole-brain functional connectivityBrain network patternsGlucose toleranceBlood insulinObesityOverweightPathophysiological phenotypesFunctional connectivity networksFunctional connectivityMilkshake consumptionBrain correlatesBrain fingerprintsBMIAdiposityBrainCircumferenceConnectivity networksFatDiabetesPathophysiologyCentral roleInsulinShort-Term Consumption of Sucralose with, but Not without, Carbohydrate Impairs Neural and Metabolic Sensitivity to Sugar in Humans
Dalenberg JR, Patel BP, Denis R, Veldhuizen MG, Nakamura Y, Vinke PC, Luquet S, Small DM. Short-Term Consumption of Sucralose with, but Not without, Carbohydrate Impairs Neural and Metabolic Sensitivity to Sugar in Humans. Cell Metabolism 2020, 31: 493-502.e7. PMID: 32130881, PMCID: PMC7784207, DOI: 10.1016/j.cmet.2020.01.014.Peer-Reviewed Original ResearchConceptsGlucose metabolismPrevalence of obesityType 2 diabetesSugar-sweetened beveragesConsumption of sucraloseHealthy human participantsInsulin sensitivityTerm consumptionTaste perceptionMetabolismLong-term decreaseSweet tasteMetabolic sensitivityComorbiditiesGeneral consensusObesityDiabetesHuman participantsBeveragesMidbrainPrevalenceBrainSimilar relationship
2019
Processed foods and food reward
Small DM, DiFeliceantonio AG. Processed foods and food reward. Science 2019, 363: 346-347. PMID: 30679360, DOI: 10.1126/science.aav0556.Peer-Reviewed Original Research
2018
Food Intake Recruits Orosensory and Post-ingestive Dopaminergic Circuits to Affect Eating Desire in Humans
Thanarajah SE, Backes H, DiFeliceantonio AG, Albus K, Cremer AL, Hanssen R, Lippert RN, Cornely OA, Small DM, Brüning JC, Tittgemeyer M. Food Intake Recruits Orosensory and Post-ingestive Dopaminergic Circuits to Affect Eating Desire in Humans. Cell Metabolism 2018, 29: 695-706.e4. PMID: 30595479, DOI: 10.1016/j.cmet.2018.12.006.Peer-Reviewed Original ResearchConceptsDopaminergic circuitsHigher cognitive centersSegregated brain regionsPeripheral physiological signalsPalatable food intakeReward valueDopamine releaseCognitive centersSubjective desireBrain regionsBrain areasUnderlying reinforcementFood intakeDorsal striatumRole of brainPhysiological signalsFood selection behaviorIntegrative pathwaysFMRIDesirePET methodBrainHumansIntakeSelection behavior
2016
Editorial overview: Diet, behavior and brain function: You are what you eat: Effects of the modern food environment on brain and behavior
Small D, la Fleur S. Editorial overview: Diet, behavior and brain function: You are what you eat: Effects of the modern food environment on brain and behavior. Current Opinion In Behavioral Sciences 2016, 9: v-viii. DOI: 10.1016/j.cobeha.2016.05.001.Peer-Reviewed Original Research
2015
Mapping Brain Activity in Response to Taste Stimulation
Small D, Faurion A. Mapping Brain Activity in Response to Taste Stimulation. 2015, 775-794. DOI: 10.1002/9781118971758.ch35.Peer-Reviewed Original Research
2006
Central Gustatory Processing in Humans
Small DM. Central Gustatory Processing in Humans. Advances In Oto-Rhino-Laryngology 2006, 63: 191-220. PMID: 16733340, DOI: 10.1159/000093761.Peer-Reviewed Original Research
2004
Crossmodal integration – insights from the chemical senses
Small D. Crossmodal integration – insights from the chemical senses. Trends In Neurosciences 2004, 27: 120-123. PMID: 15046082, DOI: 10.1016/j.tins.2004.01.002.Peer-Reviewed Original ResearchConceptsSuperior temporal sulcusStudy of auditionMultisensory integrationNeural correlatesTemporal sulcusVisual cuesOrbitofrontal cortexAssociation cortexHuman brainCrossmodalChemical sensesCortexAuditionCuesCongruencySomatosensationSulcusSensesCorrelatesOdor detectionFacilitationUnderstandingNew studiesBrain