2009
Conservation and dispersion of sequence and function in fungal TRK potassium transporters: focus on Candida albicans
Miranda M, Bashi E, Vylkova S, Edgerton M, Slayman C, Rivetta A. Conservation and dispersion of sequence and function in fungal TRK potassium transporters: focus on Candida albicans. FEMS Yeast Research 2009, 9: 278-292. PMID: 19175416, DOI: 10.1111/j.1567-1364.2008.00471.x.Peer-Reviewed Original ResearchMeSH KeywordsCandida albicansCation Transport ProteinsChloridesConserved SequenceFungal ProteinsModels, BiologicalModels, MolecularPhylogenyPolymorphism, Single NucleotidePotassiumProtein ConformationProtein Structure, TertiarySaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSequence Homology, Amino AcidConceptsPotassium transportersHuman pathogen Candida albicansTrk potassium transportersPathogen Candida albicansDetailed molecular investigationAnimal cellsSingle nucleotide polymorphismsDNA sequencesS. cerevisiaeComplete sequenceC. albicansTrk proteinSequence analysisCandida albicansInhibitor sensitivityFunctional comparisonNucleotide polymorphismsSelective drug actionMolecular investigationsAntimicrobial peptidesHomologuesPotential targetSecondary functionSalivary antimicrobial peptidesProtein
2005
Quantitative Modeling of Chloride Conductance in Yeast TRK Potassium Transporters
Rivetta A, Slayman C, Kuroda T. Quantitative Modeling of Chloride Conductance in Yeast TRK Potassium Transporters. Biophysical Journal 2005, 89: 2412-2426. PMID: 16040756, PMCID: PMC1366741, DOI: 10.1529/biophysj.105.066712.Peer-Reviewed Original ResearchConceptsTrk proteinTrk potassium transportersPotassium transportersYeast spheroplastsPlasma membraneCentral poreNegative membrane voltagesProteinActive accumulationChloride conductanceChloride currentsMembrane dielectricMembrane voltageSaccharomycesSpheroplastsFungiPlantsTransportersBacteriaConductanceMembrane slope conductanceHypothetical structural modelStructural modelMembraneSlope conductance