Clinicopathologic and Genomic Features Associated with Brain Metastasis After Resection of Lung Adenocarcinoma
Dunne E, Fick C, Mastrogiacomo B, Tan K, Toumbacaris N, Vanstraelen S, Rocco G, Chaft J, Iyengar P, Gomez D, Adusumilli P, Park B, Isbell J, Bott M, Sihag S, Molena D, Huang J, Jones D. Clinicopathologic and Genomic Features Associated with Brain Metastasis After Resection of Lung Adenocarcinoma. JTCVS Open 2024 DOI: 10.1016/j.xjon.2024.09.030.Peer-Reviewed Original ResearchResection of lung adenocarcinomaMaximum standardized uptake valueDevelopment of brain metastasesBrain metastasesStandardized uptake valueNeoadjuvant therapyLung adenocarcinomaAssociated with developmentLymphovascular invasionTP53 mutationsUptake valueCumulative incidence of brain metastasesMarker of aggressive tumor biologyHighest maximum standardized uptake valueLack of extracranial metastasesIncidence of brain metastasesNext-generation sequencingPanel next-generation sequencingAssociated with better survivalStage III diseaseMedian follow-upAggressive tumor biologyBetter performance statusAssociated with brain metastasisStereotactic radiosurgeryHigh-Risk Features Associated with Recurrence in Stage I Lung Adenocarcinoma
Fick C, Dunne E, Vanstraelen S, Toumbacaris N, Tan K, Rocco G, Molena D, Huang J, Park B, Rekhtman N, Travis W, Chaft J, Bott M, Rusch V, Adusumilli P, Sihag S, Isbell J, Jones D. High-Risk Features Associated with Recurrence in Stage I Lung Adenocarcinoma. Journal Of Thoracic And Cardiovascular Surgery 2024 PMID: 38788834, PMCID: PMC11582076, DOI: 10.1016/j.jtcvs.2024.05.009.Peer-Reviewed Original ResearchCumulative incidence of recurrenceStage I lung adenocarcinomaIncidence of recurrenceClinicopathological featuresStage I LUADCumulative incidenceHighest maximum standardized uptake valueMaximum standardized uptake valueRetrospective analysis of patientsHigh risk of recurrenceHigh riskHistory of lung cancerStage I diseaseStandardized uptake valueVisceral pleural invasionHigh-risk featuresHazard of recurrenceAssociated with recurrenceFeatures associated with recurrenceRisk of recurrenceAnalysis of patientsPrognosis of patientsDay of surgeryR0 resectionSublobar resection