2022
Expert Panel Consensus on Management of Advanced Cancer-related Pain in Individuals with Opioid Use Disorder
Merlin J, Khodyakov D, Arnold R, Bulls H, Dao E, Kapo J, King C, Meier D, Paice J, Ritchie C, Liebschutz J. Expert Panel Consensus on Management of Advanced Cancer-related Pain in Individuals with Opioid Use Disorder. Journal Of Pain 2022, 23: 60. DOI: 10.1016/j.jpain.2022.03.226.Peer-Reviewed Original ResearchBuprenorphine/naloxoneFull agonist opioidsUncertain appropriatenessAdvanced cancerPalliative careCancer pain management strategiesCancer-related painAdvanced cancer painPain management strategiesOpioid use disorderExpert panel consensusConsensus-based guidanceCancer painDay dosingBuprenorphine/Optimal dosingMethadone clinicsUse disordersPatientsNaloxonePanel consensusPrognosisMethadoneHealth FoundationPainExpanding Inpatient Addiction Consult Services Through Accountable Care Organizations for Medicaid Enrollees: A Modeling Study
King C, Cook R, Korthuis P, McCarty D, Morris C, Englander H. Expanding Inpatient Addiction Consult Services Through Accountable Care Organizations for Medicaid Enrollees: A Modeling Study. Journal Of Addiction Medicine 2022, 16: 570-576. PMID: 35135988, PMCID: PMC9357852, DOI: 10.1097/adm.0000000000000972.Peer-Reviewed Original ResearchConceptsOpioid use disorderCoordinated Care OrganizationsAccountable care organizationsTreatment engagementHospitalized patientsUse disordersCare organizationsAddiction consult serviceMedicaid accountable care organizationsOut-patient careSubstance use disordersStudy objectiveACS careMore patientsOUD treatmentOUD careOutpatient treatmentConsult serviceMedicaid enrolleesMedicaid patientsTreatment accessMedicaid dataPatientsService careAddiction careDifferences in the Delivery of Medications for Opioid use Disorder during Hospitalization by Racial Categories: A Retrospective Cohort Analysis;
Priest K, King C, Englander H, Lovejoy T, McCarty D. Differences in the Delivery of Medications for Opioid use Disorder during Hospitalization by Racial Categories: A Retrospective Cohort Analysis;. Substance Use & Addiction Journal 2022, 43: 1251-1259. PMID: 35670778, PMCID: PMC10292919, DOI: 10.1080/08897077.2022.2074601.Peer-Reviewed Original ResearchConceptsOpioid use disorderVeterans Health AdministrationWhite patientsUse disordersMOUD deliveryBlack patientsDelivery of buprenorphineType of MOUDRetrospective cohort analysisAcute care hospitalsCOVID-19 pandemic continuesDelivery of medicationsOutpatient clinical environmentLogistic regression modelsMOUD accessAddiction treatment systemCare hospitalStudy cohortSurgical hospitalizationMean ageCohort analysisHospitalizationMOUDPatientsBuprenorphine
2021
Expert Panel Consensus on Management of Advanced Cancer–Related Pain in Individuals With Opioid Use Disorder
Merlin JS, Khodyakov D, Arnold R, Bulls HW, Dao E, Kapo J, King C, Meier D, Paice J, Ritchie C, Liebschutz JM. Expert Panel Consensus on Management of Advanced Cancer–Related Pain in Individuals With Opioid Use Disorder. JAMA Network Open 2021, 4: e2139968. PMID: 34962565, DOI: 10.1001/jamanetworkopen.2021.39968.Peer-Reviewed Original ResearchConceptsOpioid use disorderFull agonist opioidsAdvanced cancerUncertain appropriatenessCancer painPalliative careUse disordersCancer pain managementAppropriateness of managementExpert panel consensusConsensus-based guidanceImportant comorbidityOpioid medicationsPain managementMethadone clinicsPainPatientsPanel consensusPrognosisCancerMethadoneDelphi processExpert panelMonthsOpioidsSimulating the impact of Addiction Consult Services in the context of drug supply contamination, hospitalizations, and drug-related mortality
King C, Cook R, Wheelock H, Korthuis P, Leahy J, Goff A, Morris C, Englander H. Simulating the impact of Addiction Consult Services in the context of drug supply contamination, hospitalizations, and drug-related mortality. International Journal Of Drug Policy 2021, 100: 103525. PMID: 34837879, PMCID: PMC8810590, DOI: 10.1016/j.drugpo.2021.103525.Peer-Reviewed Original ResearchConceptsAddiction consult serviceOpioid use disorderDrug-related deathsConsult serviceHospital dischargeCare systemDrug-related causesOpioid-related deathsDrug supplyRisk of overdoseDrug-related mortalityOpioid overdose deathsHarm reduction interventionsAdult patientsOUD patientsHospital admissionOpioid overdosesEffective treatmentOverdose deathsSimulated cohortPatientsUse disordersReduction interventionsHospitalizationDeathCorrelates of days of medication for opioid use disorder exposure among people living with HIV in Northern Vietnam
Button D, Cook R, King C, Khuyen T, Kunkel L, Bart G, Thuy D, Nguyen D, Blazes C, Giang L, Korthuis P. Correlates of days of medication for opioid use disorder exposure among people living with HIV in Northern Vietnam. International Journal Of Drug Policy 2021, 100: 103503. PMID: 34768124, PMCID: PMC8810676, DOI: 10.1016/j.drugpo.2021.103503.Peer-Reviewed Original ResearchConceptsMethadone maintenance therapyTreatment exposureMultivariate modelOpioid use disorderDisorder exposureHIV clinicMaintenance therapyPrimary outcomeUse disordersNegative binomial regressionMOUDHIVMedicationsBinomial regressionPatientsExposureDaysMonthsOUDParticipantsBuprenorphineMethadoneClinicReferralTherapyDesigning and validating a Markov model for hospital-based addiction consult service impact on 12-month drug and non-drug related mortality
King C, Englander H, Korthuis P, Barocas J, McConnell K, Morris C, Cook R. Designing and validating a Markov model for hospital-based addiction consult service impact on 12-month drug and non-drug related mortality. PLOS ONE 2021, 16: e0256793. PMID: 34506517, PMCID: PMC8432751, DOI: 10.1371/journal.pone.0256793.Peer-Reviewed Original ResearchConceptsAddiction consult serviceOpioid use disorderDrug-related deathsHospitalized patientsOUD careRelated mortalityPercent of patientsNon-drug related deathTrajectory of careSubstance use treatmentLogistic regression modelsACS careOUD treatmentPatient survivalRelated deathsSUD careConsult serviceMedicaid dataPatientsUse disordersMortalityUse treatmentCareBayesian logistic regression modelDeathCauses of Death in the 12 Months After Hospital Discharge Among Patients With Opioid Use Disorder
King C, Cook R, Korthuis P, Morris C, Englander H. Causes of Death in the 12 Months After Hospital Discharge Among Patients With Opioid Use Disorder. Journal Of Addiction Medicine 2021, 16: 466-469. PMID: 34510087, PMCID: PMC8907339, DOI: 10.1097/adm.0000000000000915.Peer-Reviewed Original ResearchConceptsOpioid use disorderCause of deathDrug-related deathsUse disordersHospitalized patientsDiagnosis of OUDGeneral hospital admissionsPost-discharge mortalityDrug-related causesAverage hospital lengthRisk of deathSubstance use disordersHospital lengthHospital dischargeHospital admissionMedicaid insuranceOUD diagnosisDrug overdoseMedicaid patientsFrequent causeHigh riskGeneral populationPatientsAverage ageCare systemUnderstanding the impact of the SARS-COV-2 pandemic on hospitalized patients with substance use disorder
King C, Vega T, Button D, Nicolaidis C, Gregg J, Englander H. Understanding the impact of the SARS-COV-2 pandemic on hospitalized patients with substance use disorder. PLOS ONE 2021, 16: e0247951. PMID: 33635926, PMCID: PMC7909702, DOI: 10.1371/journal.pone.0247951.Peer-Reviewed Original ResearchConceptsSubstance use disordersSARS-CoV-2 pandemicHospitalized patientsUse disordersHospital policy changesAcademic medical centerExperiences of healthcareAcute illnessOutpatient careMedical CenterPatientsHospitalCommunity resourcesDisordersPandemicQualitative studyThematic analysisSemi-structured interviewsSurvival adaptationHospitalizationIllnessMain themesCareTrust in Hospital Physicians Among Patients With Substance Use Disorder Referred to an Addiction Consult Service: A Mixed-methods Study
King C, Collins D, Patten A, Nicolaidis C, Englander H. Trust in Hospital Physicians Among Patients With Substance Use Disorder Referred to an Addiction Consult Service: A Mixed-methods Study. Journal Of Addiction Medicine 2021, 16: 41-48. PMID: 33577229, PMCID: PMC8349928, DOI: 10.1097/adm.0000000000000819.Peer-Reviewed Original ResearchConceptsAddiction consult serviceSubstance use disordersConsult serviceUse disordersAddiction medicine serviceGroup of patientsPatient-physician relationshipHospital dischargeHospitalized patientsPrior hospitalizationMedicine servicePatientsHospital physiciansHospitalized peopleHealthcare providersHospitalizationHospital trustsProvider trustMixed-methods studyMost participantsQualitative themesPhysiciansBaselineCareDisorders
2020
Evaluating new paralysis, mortality, and readmission among subgroups of patients with spinal epidural abscess: A latent class analysis
Brown P, Phillipi G, King C, Tanski M, Sullivan P. Evaluating new paralysis, mortality, and readmission among subgroups of patients with spinal epidural abscess: A latent class analysis. PLOS ONE 2020, 15: e0238853. PMID: 32915861, PMCID: PMC7485888, DOI: 10.1371/journal.pone.0238853.Peer-Reviewed Original ResearchConceptsSpinal epidural abscessSubgroup of patientsClinical outcomesPatient populationGroup 2Group 1Longer hospital courseSubstance use disorder diagnosisLatent class analysisSubstance use disordersChi-square testCharacteristics of subgroupsHospital mortalityEpidural abscessHospital courseMedical comorbiditiesSignificant morbidityVascular accessRisk factorsClinical subgroupsHealth centersSupport patientsHigh riskPatientsSubsequent mortalityPatterns of substance use before and after hospitalization among patients seen by an inpatient addiction consult service: A latent transition analysis
King C, Nicolaidis C, Korthuis P, Priest K, Englander H. Patterns of substance use before and after hospitalization among patients seen by an inpatient addiction consult service: A latent transition analysis. Journal Of Substance Use And Addiction Treatment 2020, 118: 108121. PMID: 32972645, PMCID: PMC8244750, DOI: 10.1016/j.jsat.2020.108121.Peer-Reviewed Original ResearchConceptsAddiction consult serviceSubstance use disordersHospitalized patientsPolysubstance useUse disordersSubstance useOpioid useConsult serviceBaseline opioid useHalf of patientsProspective cohort studyOpioid use disorderSelf-reported substance useSubstance use scoresDays posthospitalizationCohort studyHospital admissionClinical managementDifferent followHealth centersAmphetamine useLatent transition analysisPatientsAcademic health centersHospital providersCommunity Outreach for Navajo People Living with Diabetes: Who Benefits Most?
Trevisi L, Orav J, Atwood S, Brown C, Curley C, King C, Muskett O, Sehn H, Nelson A, Begay M, Shin S. Community Outreach for Navajo People Living with Diabetes: Who Benefits Most? Preventing Chronic Disease 2020, 17: e68. PMID: 32701432, PMCID: PMC7380292, DOI: 10.5888/pcd17.200068.Peer-Reviewed Original ResearchConceptsPrimary care providersBaseline HbACommunity Health RepresentativesMental health conditionsCare providersCOPE patientsHealth conditionsGlycated hemoglobin APrimary care physiciansRoutine health recordsPatient empowerment interventionCommunity outreachDe-identified dataPreferred languageCare physiciansCOPE interventionPatientsHealth representativesDiabetesHealth recordsHemoglobin AHbALinear mixed modelsInterventionEmpowerment interventionTime-to-completed-imaging, survival and function in patients with spinal epidural abscess: Description of a series of 34 patients, 2015–2018
King C, Fisher C, Brown P, Priest K, Tanski M, Sullivan P. Time-to-completed-imaging, survival and function in patients with spinal epidural abscess: Description of a series of 34 patients, 2015–2018. BMC Health Services Research 2020, 20: 119. PMID: 32059715, PMCID: PMC7023770, DOI: 10.1186/s12913-020-4973-5.Peer-Reviewed Original ResearchConceptsIntravenous drug useDrug useEpidural abscessEmergency departmentRisk factorsMethodsThis retrospective cohort studySingle academic medical centerMean timeRetrospective cohort studySpinal epidural abscessLife-threatening infectionsAcademic medical centerMulti-center approachShorter mean timeCohort studyNeurologic symptomsBack painClassic triadSignificant morbiditySurgical interventionSingle hospitalQuality improvement workMedical CenterPrompt identificationPatients
2019
Predictors of Opioid and Alcohol Pharmacotherapy Initiation at Hospital Discharge Among Patients Seen by an Inpatient Addiction Consult Service.
Englander H, King C, Nicolaidis C, Collins D, Patten A, Gregg J, Korthuis P. Predictors of Opioid and Alcohol Pharmacotherapy Initiation at Hospital Discharge Among Patients Seen by an Inpatient Addiction Consult Service. Journal Of Addiction Medicine 2019, 14: 415-422. PMID: 31868830, PMCID: PMC7954140, DOI: 10.1097/adm.0000000000000611.Peer-Reviewed Original ResearchConceptsImproving Addiction Care TeamAddiction consult serviceSubstance use disordersUse disordersConsult serviceTreatment-related factorsOpioid use disorderMethadone maintenance treatmentAcademic medical centerAlcohol use disorderPartner substance useSevere OUDMedication initiationPatient demographicsMaintenance treatmentPatient surveyCare teamClinical dataMedical CenterSocial determinantsLogistic regressionHospital's roleSubstance useDisordersPatientsIntegrating community health representatives with health care systems: clinical outcomes among individuals with diabetes in Navajo Nation
Trevisi L, Orav J, Atwood S, Brown C, Curley C, King C, Muskett O, Sehn H, Nelson K, Begay M, Shin S. Integrating community health representatives with health care systems: clinical outcomes among individuals with diabetes in Navajo Nation. International Journal For Equity In Health 2019, 18: 183. PMID: 31771603, PMCID: PMC6880375, DOI: 10.1186/s12939-019-1097-9.Peer-Reviewed Original ResearchConceptsCommunity Health RepresentativesClinical outcomesHealth representativesSystolic blood pressureBody mass indexRoutine clinical dataLow-density lipoproteinIntegrated care teamsPatient empowerment interventionHealth care systemHealth service information systemCOPE groupCOPE patientsClinical characteristicsBlood pressureDiabetes mellitusMass indexCare teamClinical dataLipid levelsHome visitsCOPE interventionNavajo populationPatientsClinical sites
2018
Identifying risk factors for 30-day readmission events among American Indian patients with diabetes in the Four Corners region of the southwest from 2009 to 2016
King C, Atwood S, Lozada M, Nelson A, Brown C, Sabo S, Curley C, Muskett O, Orav E, Shin S. Identifying risk factors for 30-day readmission events among American Indian patients with diabetes in the Four Corners region of the southwest from 2009 to 2016. PLOS ONE 2018, 13: e0195476. PMID: 30070989, PMCID: PMC6071952, DOI: 10.1371/journal.pone.0195476.Peer-Reviewed Original Research
2017
Primary care and survival among American Indian patients with diabetes in the Southwest United States: Evaluation of a cohort study at Gallup Indian Medical Center, 2009–2016
King C, Atwood S, Brown C, Nelson A, Lozada M, Wei J, Merino M, Curley C, Muskett O, Sabo S, Gampa V, Orav J, Shin S. Primary care and survival among American Indian patients with diabetes in the Southwest United States: Evaluation of a cohort study at Gallup Indian Medical Center, 2009–2016. Primary Care Diabetes 2017, 12: 212-217. PMID: 29229284, DOI: 10.1016/j.pcd.2017.11.003.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsAgedAged, 80 and overCause of DeathChildCohort StudiesDatabases, FactualDiabetes MellitusFemaleHospitalizationHumansIndians, North AmericanKaplan-Meier EstimateMaleMiddle AgedPrimary Health CareProportional Hazards ModelsRetrospective StudiesRisk AssessmentSex FactorsSouthwestern United StatesStatistics, NonparametricSurvival AnalysisYoung AdultConceptsPrimary care providersLog-rank testAmerican Indian patientsCare providersIndian patientsCox proportional hazards analysisStudy periodProportional hazards analysisMedian survival timeCause mortalityCohort studyOverall survivalImproved survivalFirst admissionUnadjusted analysesPrimary careMedical CenterSurvival timePatientsAdmissionDiabetesSurvivalHealthcare deliverySignificant differencesHazard analysisSurgical referral coordination from a first-level hospital: a prospective case study from rural Nepal
Fleming M, King C, Rajeev S, Baruwal A, Schwarz D, Schwarz R, Khadka N, Pande S, Khanal S, Acharya B, Benton A, Rogers SO, Panizales M, Gyorki D, McGee H, Shaye D, Maru D. Surgical referral coordination from a first-level hospital: a prospective case study from rural Nepal. BMC Health Services Research 2017, 17: 676. PMID: 28946885, PMCID: PMC5613391, DOI: 10.1186/s12913-017-2624-2.Peer-Reviewed Original ResearchConceptsHealth systems frameworkWorld Health Organization health systems frameworkFirst-level hospitalsProspective case studySurgical careSurgical servicesReferral systemGeneral surgical conditionsCare coordination processLocal surgical capacityRural NepalComprehensive surgical careSurgical specialty servicesDistrict hospitalSurgical conditionsSpecialty servicesSurgical capacityReferral processDiagnostic examinationsCoordination programPatientsHospitalReferral coordinationIndirect costsCommon type