2024
Patient-specific ascending aortic intervention criteria
Kalogerakos P, Zafar M, Li Y, Ellauzi H, Mukherjee S, Ziganshin B, Rizzo J, Elefteriades J. Patient-specific ascending aortic intervention criteria. European Journal Of Cardio-Thoracic Surgery 2024, 65: ezae162. PMID: 38632077, DOI: 10.1093/ejcts/ezae162.Peer-Reviewed Original ResearchAdverse aortic eventsRisk of adverse eventsAortic eventsAortic rootAneurysm patientsAscending aortaAdverse eventsIncreased risk of adverse eventsThoracic aortic aneurysm patientsAscending aortic aneurysmHigher risk of adverse eventsAortic aneurysm patientsAscending thoracic aortic aneurysm patientsBody surface areaGeneral populationPersonalized risk stratificationAortic diameterAneurysm locationRisk stratificationAortic aneurysmIncreased riskAscending diameterPatientsHigh riskZ-score
2023
Midterm follow-up of composite graft replacement of the aortic root (30-year experience)—remarkably safe, effective, and durable
Jeoffrey S, Zafar M, Velasco J, Khattak A, Ellauzi H, Nasir A, Kalyanasundaram A, Ziganshin B, Elefteriades J. Midterm follow-up of composite graft replacement of the aortic root (30-year experience)—remarkably safe, effective, and durable. JTCVS Open 2023, 17: 1-13. PMID: 38420531, PMCID: PMC10897671, DOI: 10.1016/j.xjon.2023.11.007.Peer-Reviewed Original ResearchAortic root replacementOperative mortalityTerm outcomesDistal aortic segmentsLong-term bleedingAortic root diseaseComposite graft replacementType A DissectionFirst-time operationsAge/genderARR patientsConcomitant CABGLate reoperationAcute typeRoot replacementAdverse eventsGraft failureGraft replacementRedo proceduresCabrol procedureUrgent operationAortic rootAortic segmentsPatientsOperative choiceEvidence Accumulates: Patients with Ascending Aneurysms Are Strongly Protected from Atherosclerotic Disease
Waldron C, Zafar M, Ziganshin B, Weininger G, Grewal N, Elefteriades J. Evidence Accumulates: Patients with Ascending Aneurysms Are Strongly Protected from Atherosclerotic Disease. International Journal Of Molecular Sciences 2023, 24: 15640. PMID: 37958625, PMCID: PMC10650782, DOI: 10.3390/ijms242115640.Peer-Reviewed Original ResearchConceptsThoracic aortic aneurysmAortic aneurysmCarotid intima-media thicknessLow-density lipoprotein levelsIntima-media thicknessDevelopment of atherosclerosisMatrix metalloproteinase proteinsAscending aneurysmAortic calcificationAtherosclerotic diseaseLipoprotein levelsMyocardial infarctionLeading causeAneurysmsMetalloproteinase proteinsGrowth factorProtective relationshipDiseasePossible mechanismCurrent understandingMorbidityInfarctionAtherosclerosisPatientsPathophysiology
2014
Surgical management of thoracoabdominal aneurysms
Ziganshin BA, Elefteriades JA. Surgical management of thoracoabdominal aneurysms. Heart 2014, 100: 1577. PMID: 25092876, DOI: 10.1136/heartjnl-2013-305131.Peer-Reviewed Original ResearchConceptsThoracoabdominal aneurysmsSurgical managementApplication of hypothermiaCerebrospinal fluid drainageType of treatmentParaplegia ratePostoperative mortalityHospital stayComplication rateSurgical treatmentHeart bypassHybrid repairTreatment adjunctsMorbid conditionsFluid drainageHigh mortalityTAAASignificant decreaseAneurysmsTreatmentMortalityNeuromonitoringPatientsStayAortaStatistical Challenges in Identifying Risk Factors for Aortic Disease
Rizzo JA, Chen J, Fang H, Ziganshin BA, Elefteriades JA. Statistical Challenges in Identifying Risk Factors for Aortic Disease. Aorta 2014, 02: 45-55. PMID: 26798715, PMCID: PMC4682756, DOI: 10.12945/j.aorta.2014.14-019.Peer-Reviewed Original Research