2005
Mechanistic and modular approaches to modeling and inference of cellular regulatory networks
Kholodenko B, Bruggeman F, Sauro H. Mechanistic and modular approaches to modeling and inference of cellular regulatory networks. Topics In Current Genetics 2005, 13: 143-159. DOI: 10.1007/b136809.Peer-Reviewed Original ResearchReaction-diffusion equationsCellular regulatory networksRegulatory networksSystems biologyMolecular mechanismsBiochemical networksNetwork inferencePhysiological responsesNew insightsModeling approachChemical kineticsInferenceMolecular dynamics simulationsEquationsModelingBiologyComputational modelingNetworkModular approachDynamics simulationsApproachSimulationsNovel approach
1996
Control analysis of glycolytic oscillations
Bier M, Teusink B, Kholodenko B, Westerhoff H. Control analysis of glycolytic oscillations. Biophysical Chemistry 1996, 62: 15-24. PMID: 8962468, DOI: 10.1016/s0301-4622(96)02195-3.Peer-Reviewed Original ResearchSteady-State Characterization of Systems with Moiety-Conservations Made Easy: Matrix Equations of Metabolic Control Analysis and Biochemical System Theory
Cascante M, Puigjaner J, Kholodenko B. Steady-State Characterization of Systems with Moiety-Conservations Made Easy: Matrix Equations of Metabolic Control Analysis and Biochemical System Theory. Journal Of Theoretical Biology 1996, 178: 1-6. DOI: 10.1006/jtbi.1996.0001.Peer-Reviewed Original ResearchMatrix equationBiochemical systems theorySingle matrix inversionLocal propertiesMatrix inversionSystems theoryLink matrixMetabolic control analysisControl propertiesEquationsMoiety conservationSensitivity theoryControl analysisTheoryStructural propertiesMatrixPropertiesState characterizationInversion