2023
Childhood adversities and risk of posttraumatic stress disorder and major depression following a motor vehicle collision in adulthood
Ziobrowski H, Holt-Gosselin B, Petukhova M, King A, Lee S, House S, Beaudoin F, An X, Stevens J, Zeng D, Neylan T, Clifford G, Linnstaedt S, Germine L, Bollen K, Rauch S, Haran J, Storrow A, Lewandowski C, Musey P, Hendry P, Sheikh S, Jones C, Punches B, Kurz M, Swor R, Hudak L, Pascual J, Seamon M, Harris E, Pearson C, Merchant R, Domeier R, Rathlev N, O'Neil B, Sergot P, Sanchez L, Bruce S, Miller M, Pietrzak R, Joormann J, Barch D, Pizzagalli D, Harte S, Elliott J, Ressler K, McLean S, Koenen K, Kessler R. Childhood adversities and risk of posttraumatic stress disorder and major depression following a motor vehicle collision in adulthood. Epidemiology And Psychiatric Sciences 2023, 32: e1. PMID: 36624694, PMCID: PMC9879881, DOI: 10.1017/s2045796022000798.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderAdverse posttraumatic neuropsychiatric sequelaeChildhood adversityEmotional abuseStress disorderEmotional neglectChronic posttraumatic stress disorderSelf-report criteriaPeritraumatic symptomsTraumatic eventsPTSD ChecklistSexual abusePhysical neglectMajor depressive episodeMotor vehicle collisionsPhysical abuseDSM-5CA measuresBullyingAbuseStrongest predictorAdversityTrauma studiesDichotomous measureExposure frequency
2022
Lack of Robust Associations Between Prepandemic Coping Strategies and Frontolimbic Circuitry With Depression and Anxiety Symptoms During the COVID-19 Pandemic: A Preregistered Longitudinal Study
Holt-Gosselin B, Cohodes E, McCauley S, Foster J, Odriozola P, Zacharek S, Kribakaran S, Haberman J, Hodges H, Gee D. Lack of Robust Associations Between Prepandemic Coping Strategies and Frontolimbic Circuitry With Depression and Anxiety Symptoms During the COVID-19 Pandemic: A Preregistered Longitudinal Study. Behavioral Neuroscience 2022, 136: 528-540. PMID: 36395014, PMCID: PMC9884515, DOI: 10.1037/bne0000534.Peer-Reviewed Original ResearchConceptsFrontolimbic circuitryAnxiety symptomsFunctional connectivityMental health outcomesCoping strategiesResting-state functional magnetic resonanceAdaptive coping strategiesLongitudinal studyFunctional magnetic resonanceMental health problemsACC functional connectivityAdaptive copingPreregistered hypothesesInternalizing symptomsNeurobehavioral factorsEmotional responsesPreregistered studyNeurobiological factorsOngoing stressorsElevated symptomsDepression symptomsHealth outcomesCopingCOVID-19 pandemicRobust association
2021
Greater baseline connectivity of the salience and negative affect circuits are associated with natural improvements in anxiety over time in untreated participants
Holt-Gosselin B, Keller AS, Chesnut M, Ling R, Grisanzio KA, Williams LM. Greater baseline connectivity of the salience and negative affect circuits are associated with natural improvements in anxiety over time in untreated participants. Journal Of Affective Disorders 2021, 295: 366-376. PMID: 34492429, DOI: 10.1016/j.jad.2021.08.039.Peer-Reviewed Original ResearchConceptsAnxiety symptom improvementNegative affect circuitSymptoms of anxietyCognitive controlSymptom improvementSad facesLifestyle activitiesPositive affectBehavioral therapyCircuit connectivityBaseline connectivityDefault modeRight insulaPsychosocial functionSocial interactionAnxiety improvementActivity engagementDepression symptomsAnxietySalienceNeural circuit functionNatural improvementUntreated participantsCausal inferenceLimited research
2019
Worth working for: The influence of effort costs on teens’ choices during a novel decision making game
Sullivan-Toole H, DePasque S, Holt-Gosselin B, Galván A. Worth working for: The influence of effort costs on teens’ choices during a novel decision making game. Developmental Cognitive Neuroscience 2019, 37: 100652. PMID: 31075712, PMCID: PMC6969283, DOI: 10.1016/j.dcn.2019.100652.Peer-Reviewed Original ResearchConceptsGoal pursuitAdolescent decisionEffort-based decision makingPhysical effort costsEffort costsDecision makingEffect of effortReward responsivityTask validityTask motivationDevelopmental differencesDevelopmental researchDevelopmental trajectoriesAppropriate tasksEffort requirementsPreliminary evidenceYoung adultsPrevious researchNew experiencesAdolescenceAdolescentsNovel decisionAdultsWillingnessMaking