Coping Strategies, Neural Structure, and Depression and Anxiety During the COVID-19 Pandemic: A Longitudinal Study in a Naturalistic Sample Spanning Clinical Diagnoses and Subclinical Symptoms
Holt-Gosselin B, Tozzi L, Ramirez CA, Gotlib IH, Williams LM. Coping Strategies, Neural Structure, and Depression and Anxiety During the COVID-19 Pandemic: A Longitudinal Study in a Naturalistic Sample Spanning Clinical Diagnoses and Subclinical Symptoms. Biological Psychiatry Global Open Science 2021, 1: 261-271. PMID: 34604834, PMCID: PMC8479487, DOI: 10.1016/j.bpsgos.2021.06.007.Peer-Reviewed Original ResearchAnxious arousal symptomsMaladaptive coping strategiesArousal symptomsCoping strategiesSubclinical symptomsBrain regionsNeural structuresGray matter volumePreregistered hypothesesNeural factorsAnhedonia symptomsStressful eventsDepression symptomsGeneral linear mixed-effects modelsNaturalistic sampleLongitudinal studyMatter volumeAmygdala volumeAnxietyLower structural integrityCOVID-19 pandemicT1-weighted scansCortical thicknessPsychiatric diagnosisClinical symptomsDefault Mode Network Moderates the Relationship Between Lifestyle Changes and Natural Improvements in Clinical Symptoms Over Time in Untreated Participants
Holt-Gosselin B, Keller A, Chesnut M, Williams L. Default Mode Network Moderates the Relationship Between Lifestyle Changes and Natural Improvements in Clinical Symptoms Over Time in Untreated Participants. Biological Psychiatry 2021, 89: s111. DOI: 10.1016/j.biopsych.2021.02.287.Peer-Reviewed Original Research