2024
Artificial Intelligence Predicts Hospitalization for Acute Heart Failure Exacerbation in Patients Undergoing Myocardial Perfusion Imaging
Feher A, Bednarski B, Miller R, Shanbhag A, Lemley M, Miras L, Sinusas A, Miller E, Slomka P. Artificial Intelligence Predicts Hospitalization for Acute Heart Failure Exacerbation in Patients Undergoing Myocardial Perfusion Imaging. Journal Of Nuclear Medicine 2024, 65: jnumed.123.266761. PMID: 38548351, PMCID: PMC11064832, DOI: 10.2967/jnumed.123.266761.Peer-Reviewed Original ResearchConceptsMyocardial perfusion imagingHF hospitalizationHeart failureStress left ventricular ejection fractionPerfusion imagingHF exacerbationPredictive of HF hospitalizationsSPECT/CT myocardial perfusion imagingMyocardial perfusionInternational cohortAcute heart failure exacerbationMedian follow-upVentricular ejection fractionReceiver-operating-characteristic curveClinical risk factorsHeart failure exacerbationExternal validation cohortAcute HF exacerbationPrevent HF hospitalizationsImaging parametersCalcium scoreEjection fractionClinical parametersCT scanValidation cohort
2023
Impaired left-ventricular global longitudinal strain by feature-tracking cardiac MRI predicts mortality in systemic sclerosis
Feher A, Miller E, Peters D, Mojibian H, Sinusas A, Hinchcliff M, Baldassarre L. Impaired left-ventricular global longitudinal strain by feature-tracking cardiac MRI predicts mortality in systemic sclerosis. Rheumatology International 2023, 43: 849-858. PMID: 36894756, DOI: 10.1007/s00296-023-05294-6.Peer-Reviewed Original ResearchConceptsLate gadolinium enhancementLV-GLSSystemic sclerosisWorse survivalClinical indicationsImpaired left ventricular global longitudinal strainLeft ventricular global longitudinal strainPresence of LGECMR strainLV cardiac indexWorse LV-GLSLV ejection fractionCox regression analysisGlobal longitudinal strainLV cardiac outputGlobal radialCardiac indexOverall survivalRetrospective cohortEjection fractionPrognostic valueAdverse outcomesCardiac outputGadolinium enhancementRV strain
2021
57884 Fast strain-encoded cardiac magnetic resonance detects immune checkpoint inhibitor associated cardiotoxicity
Cuomo J, Ragheb E, Feher A, Kwan J, Huber S, Mojibian H, Peters D, Sinusas A, Baldassarre L. 57884 Fast strain-encoded cardiac magnetic resonance detects immune checkpoint inhibitor associated cardiotoxicity. Journal Of Clinical And Translational Science 2021, 5: 141-142. PMCID: PMC8827987, DOI: 10.1017/cts.2021.761.Peer-Reviewed Original ResearchImmune checkpoint inhibitorsVentricular ejection fractionLV strainCardiotoxicity groupCheckpoint inhibitorsEjection fractionProspective studyCardiac functionNormal left ventricular ejection fractionLeft ventricular ejection fractionCardiac magnetic resonance imagingCardiac magnetic resonance imaging techniquesGlobal longitudinal LV strainAbnormal troponin valuesEvidence of cardiotoxicityProportion of myocardiumLarge prospective studiesLongitudinal LV strainStudy of patientsSteady-state free precession cine imagesAbnormal cardiac functionCircumferential LV strainT2-weighted imagingMagnetic resonance imagingDysfunctional segments
2019
Molecular Imaging of the Heart
Boutagy NE, Feher A, Alkhalil I, Umoh N, Sinusas AJ. Molecular Imaging of the Heart. 2019, 9: 477-533. PMID: 30873600, DOI: 10.1002/cphy.c180007.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsCardiovascular diseaseRisk stratificationCardiovascular molecular imagingMultimodality cardiovascular imagingIschemic heart failureMolecular imagingMolecular imaging targetsPositron emission tomographySingle photon emissionNumerous cardiovascular diseasesClinical molecular imagingEjection fractionHeart failureMedical therapySystemic diseaseMyocardial infarctionPathophysiological changesCardiac functionEarly diagnosisDisease processCardiac arrhythmiasEmission tomographyCardiovascular imagingImaging strategiesPhoton emission