2024
Semaglutide utilization associated with reduced ninety-day postoperative complications following single-level posterior lumbar fusion for patients with type II diabetes
Seddio A, Gouzoulis M, Vasudevan R, Dhodapkar M, Jabbouri S, Varthi A, Rubio D, Grauer J. Semaglutide utilization associated with reduced ninety-day postoperative complications following single-level posterior lumbar fusion for patients with type II diabetes. The Spine Journal 2024 PMID: 39491749, DOI: 10.1016/j.spinee.2024.10.011.Peer-Reviewed Original ResearchSingle-level posterior lumbar fusionPosterior lumbar fusionSodium-glucose transport protein 2 inhibitorsAdverse eventsPostoperative complicationsT2DM patientsCurrent Procedural TerminologyElixhauser Comorbidity IndexED visitsLumbar fusionHospital readmissionEmergency departmentOdds of postoperative complicationsNinety-day postoperative complicationsImpact of semaglutideOdds of hospital readmissionMonths of surgeryRetrospective cohort studyPostoperative adverse eventsMinor adverse eventsType II diabetes mellitusRisk of type I errorDiagnosis of T2DMII diabetes mellitusYears of ageOutcomes following two-level Cervical Disc Arthroplasty Relative to two-level Anterior Cervical Discectomy.
Ratnasamy P, Gouzoulis M, Jabbouri S, Varthi A, Grauer J. Outcomes following two-level Cervical Disc Arthroplasty Relative to two-level Anterior Cervical Discectomy. Spine 2024 PMID: 39190404, DOI: 10.1097/brs.0000000000005131.Peer-Reviewed Original ResearchCervical disc arthroplasty patientsFive-year survivalCervical disc arthroplastyPostoperative adverse eventsSpine reoperationTwo-level cervical disc arthroplastyAdverse eventsACDF patientsPatient ageElixhauser Comorbidity IndexTreatment optionsMultivariate analysisDegenerative cervical spine pathologyTwo-level surgeryCervical spine pathologyTwo-level ACDFAnterior cervical discectomyNovel treatment optionsMinor adverse eventsCervical discectomyNo significant differenceSpine pathologyACDFReoperationComorbidity index
2023
Ninety day adverse events following single level posterior lumbar interbody fusion in patients with sickle cell disease
Dhodapkar M, Halperin S, Saifi C, Whang P, Grauer J, Varthi A. Ninety day adverse events following single level posterior lumbar interbody fusion in patients with sickle cell disease. The Spine Journal 2023, 24: 807-811. PMID: 38081460, DOI: 10.1016/j.spinee.2023.11.025.Peer-Reviewed Original ResearchPosterior lumbar interbody fusionSingle-level posterior lumbar interbody fusionSickle cell diseaseElixhauser Comorbidity IndexAdverse eventsPostoperative outcomesInterbody fusionOdds ratioCell diseaseDays adverse eventsMinor adverse eventsPostoperative adverse eventsPerioperative adverse eventsSevere adverse eventsCohort of patientsED visit ratesEmergency department visitsMultivariable logistic regressionNational administrative databaseRetrospective database studyLumbar interbody fusionSingle level posteriorComorbidity indexPLIF patientsAdult patientsLumbar Laminotomy: Variables Affecting 90-day Overall Reimbursement
Halperin S, Dhodapkar M, Gouzoulis M, Laurans M, Varthi A, Grauer J. Lumbar Laminotomy: Variables Affecting 90-day Overall Reimbursement. Journal Of The American Academy Of Orthopaedic Surgeons 2023, 32: 265-270. PMID: 38064482, DOI: 10.5435/jaaos-d-23-00365.Peer-Reviewed Original ResearchPostoperative adverse eventsAdverse eventsInsurance typePostoperative emergency department visitsPostoperative emergency departmentEmergency department visitsElixhauser Comorbidity IndexMultivariable linear regression modelsMultivariable linear regressionHealthcare deliveryIndications of traumaPostoperative readmissionsComorbidity indexInfectious diagnosisConservative treatmentPerioperative dataDepartment visitsEmergency departmentOutpatient surgeryLarge cohortSpinal proceduresExclusion criteriaDiskectomyOverall reimbursementCommon procedure
2022
Correlation of Patient Reported Satisfaction With Adverse Events Following Elective Posterior Lumbar Fusion Surgery: A Single Institution Analysis
Mercier MR, Galivanche AR, McLean R, Kammien AJ, Toombs CS, Rubio DR, Varthi AG, Grauer JN. Correlation of Patient Reported Satisfaction With Adverse Events Following Elective Posterior Lumbar Fusion Surgery: A Single Institution Analysis. North American Spine Society Journal (NASSJ) 2022, 12: 100160. PMID: 36118954, PMCID: PMC9478916, DOI: 10.1016/j.xnsj.2022.100160.Peer-Reviewed Original ResearchPosterior lumbar fusion surgeryLumbar fusion surgeryAdverse eventsHCAHPS surveyPLF surgeryFusion surgerySelf-reported patient satisfactionPostoperative adverse eventsRetrospective cohort analysisPost-discharge careSingle-institution analysisHospital Consumer AssessmentPatient satisfaction metricsCorrelation of patientsHCAHPS survey dataTop-box responsesPLF patientsSurvey response ratePatient satisfactionSingle institutionHospital experiencePatients' perceptionsHospital careCohort analysisPatientsUnderweight patients are the highest risk body mass index group for perioperative adverse events following stand-alone anterior lumbar interbody fusion
Ottesen TD, Galivanche AR, Greene JD, Malpani R, Varthi AG, Grauer JN. Underweight patients are the highest risk body mass index group for perioperative adverse events following stand-alone anterior lumbar interbody fusion. The Spine Journal 2022, 22: 1139-1148. PMID: 35231643, DOI: 10.1016/j.spinee.2022.02.012.Peer-Reviewed Original ResearchConceptsBody mass indexNational Surgical Quality Improvement Program databaseQuality Improvement Program databaseAnterior lumbar interbody fusionObese class 1Improvement Program databaseClass 2 patientsAdverse eventsUnderweight patientsBMI categoriesAdverse outcomesBMI spectrumInterbody fusionProgram databaseTwo-level anterior lumbar interbody fusionSurgeons National Surgical Quality Improvement Program databaseMultivariate analysisThirty-day adverse eventsWorld Health Organization categoriesBody mass index groupsPostoperative adverse eventsRetrospective cohort studyPerioperative adverse eventsNormal-weight subjectsPost-operative infection
2021
COVID-positive ankle fracture patients are at increased odds of perioperative surgical complications following open reduction internal fixation surgery
Mercier MR, Galivanche AR, Brand JP, Pathak N, Medvecky MJ, Varthi AG, Rubin LE, Grauer JN. COVID-positive ankle fracture patients are at increased odds of perioperative surgical complications following open reduction internal fixation surgery. PLOS ONE 2021, 16: e0262115. PMID: 34972190, PMCID: PMC8719674, DOI: 10.1371/journal.pone.0262115.Peer-Reviewed Original ResearchConceptsCOVID-positive patientsAnkle fracture surgeryPerioperative adverse eventsAdverse eventsAnkle fracture patientsFracture surgeryFracture patientsOperative interventionAnkle fracturesPropensity matchingCOVID statusOpen reduction internal fixation surgeryPerioperative adverse outcomesPerioperative surgical complicationsMinor adverse eventsPostoperative adverse eventsSerious adverse eventsChronic kidney diseaseCOVID-19 Research DatabaseLong-term outcomesInternal fixation surgeryBasis of agePropensity-score matchingPostoperative complicationsNegative patients
2014
Risk Factors for Short-term Adverse Events and Readmission After Arthroscopic Meniscectomy
Basques BA, Gardner EC, Varthi AG, Fu MC, Bohl DD, Golinvaux NS, Grauer JN. Risk Factors for Short-term Adverse Events and Readmission After Arthroscopic Meniscectomy. The American Journal Of Sports Medicine 2014, 43: 169-175. PMID: 25294869, DOI: 10.1177/0363546514551923.Peer-Reviewed Original ResearchConceptsSevere adverse eventsAdverse eventsRisk factorsMedical comorbiditiesOlder patientsArthroscopic meniscectomySurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseShort-term adverse eventsQuality Improvement Program databaseMultivariate logistic regression analysisOdds of readmissionPostoperative adverse eventsImprovement Program databaseHistory of smokingCase-control studyEvidence of osteoarthritisLevel of evidenceLogistic regression analysisComorbidity burdenPulmonary diseasePatient selectionPreoperative counselingCommon surgeryMean age