2016
Dendrite Maintenance
Katrancha S, Koleske A. Dendrite Maintenance. 2016, 317-355. DOI: 10.1007/978-4-431-56050-0_14.Peer-Reviewed Original ResearchDendritic spinesArbor stabilityDendrite arborsCytoplasmic nonreceptor tyrosine kinaseDendritic spine formationDendritic spine stabilityProper brain functionPsychiatric illnessSpine stabilityDifferent pathological statesSynaptic connectionsSpine formationBrain functionNormal agingNeurodegenerative diseasesMajor contributing factorSpinePathological statesReceptorsArborsEph receptorsContributing factorTyrosine kinaseCell surface adhesion receptorsMolecular mechanisms
2010
Increased Dendrite Branching in AβPP/PS1 Mice and Elongation of Dendrite Arbors by Fasudil Administration
Couch BA, DeMarco GJ, Gourley SL, Koleske AJ. Increased Dendrite Branching in AβPP/PS1 Mice and Elongation of Dendrite Arbors by Fasudil Administration. Journal Of Alzheimer's Disease 2010, 20: 1003-1008. PMID: 20413901, PMCID: PMC3077946, DOI: 10.3233/jad-2010-091114.Peer-Reviewed Original ResearchConceptsDendrite arborsPS1 miceAβPP/PS1 miceAmyloid-beta overproductionPS1 transgenic miceCA1 pyramidal neuronsROCK inhibitor fasudilROCK signalingPyramidal neuronsDendritic regressionFasudil administrationPharmacological reductionInhibitor fasudilTransgenic miceAlzheimer's diseaseMiceDendrite branchingRho-kinaseArborsDiseaseNeuronsSignalingAtrophyFasudilAbeta