2021
CD-1 Outbred Mice Produce Less Variable Ultrasonic Vocalizations Than FVB Inbred Mice, While Displaying a Similar Developmental Trajectory
Binder MS, Shi HD, Bordey A. CD-1 Outbred Mice Produce Less Variable Ultrasonic Vocalizations Than FVB Inbred Mice, While Displaying a Similar Developmental Trajectory. Frontiers In Psychiatry 2021, 12: 687060. PMID: 34475829, PMCID: PMC8407076, DOI: 10.3389/fpsyt.2021.687060.Peer-Reviewed Original ResearchFVB miceOutbred miceCD-1Ultrasonic vocalizationsCD-1 micePostnatal day 4Female CD-1Neurological disorder modelsNeonatal ultrasonic vocalizationsNeurological deficitsNeonatal miceCD1 miceDay 4PD 12MicePD 4Maternal careLonger durationMean amplitudeSignificant differencesUSV productionOutbred animalsDevelopmental trajectoriesMore ultrasonic vocalizationsFVB
2013
Hypoxia-inducible factor 1a is a Tsc1-regulated survival factor in newborn neurons in tuberous sclerosis complex
Feliciano DM, Zhang S, Quon JL, Bordey A. Hypoxia-inducible factor 1a is a Tsc1-regulated survival factor in newborn neurons in tuberous sclerosis complex. Human Molecular Genetics 2013, 22: 1725-1734. PMID: 23349360, PMCID: PMC3613161, DOI: 10.1093/hmg/ddt018.Peer-Reviewed Original ResearchConceptsHypoxia-inducible factor 1aTuberous sclerosis complexShort hairpin RNANewborn neuronsFactor 1ASubventricular zoneSVZ stem cellsNewborn neuron survivalNeurogenic subventricular zoneSingle-cell electroporationTranscriptional activityShRNA expressionHairpin RNAMammalian targetMolecular determinantsNovel microenvironmentNeuron deathNeuron survivalOlfactory lesionsNeonatal miceBrain lesionsStem cellsMouse modelNeuron productionSurvival advantage