2024
DNA methylation‐based telomere length is associated with HIV infection, physical frailty, cancer, and all‐cause mortality
Liang X, Aouizerat B, So‐Armah K, Cohen M, Marconi V, Xu K, Justice A. DNA methylation‐based telomere length is associated with HIV infection, physical frailty, cancer, and all‐cause mortality. Aging Cell 2024, 23: e14174. PMID: 38629454, PMCID: PMC11258465, DOI: 10.1111/acel.14174.Peer-Reviewed Original ResearchCancer prevalenceAll-cause mortalityVeterans Aging Cohort Study Biomarker CohortMortality riskPhysiological frailtyVACS IndexIncreased risk of all-cause mortalityRisk of all-cause mortalityCancer registry dataHigher cancer prevalenceHIV infectionElectronic medical recordsSelf-reported raceCoronary heart diseaseAssociated with HIV infectionIndicator of cellular agingPhysical frailtyRegistry dataSmoking statusWomen's Interagency HIV Study cohortAlcohol consumptionShorter TLTelomere lengthMedical recordsPeripheral blood mononuclear cells
2015
Sex Differences in Overall and Cause-Specific Mortality among HIV-Infected Adults on Antiretroviral Therapy in Europe, Canada and the US
Jarrin I, Moreno S, Ingle S, May M, Sterling T, Justice A, Bickel M, Crane H, Mugavero M, De Wolf F, Jung N, Cescon A, Garcia I, Elzi L, Arminio A, Krause M, Smith C, Guest J, Hessamfar M, Gill J, Sterne J, del Amo J. Sex Differences in Overall and Cause-Specific Mortality among HIV-Infected Adults on Antiretroviral Therapy in Europe, Canada and the US. Antiviral Therapy 2015, 20: 21-28. PMID: 24675571, DOI: 10.3851/imp2768.Peer-Reviewed Original ResearchConceptsNon-AIDS mortalityInjection drug useAll-causeAntiretroviral therapyAIDS-mortality rateNon-AIDS-related mortalityCause-specific mortalityCD4(+) T-cell countsNon-AIDS infectionsRates of all-causeNon-AIDS malignanciesART Cohort CollaborationT-cell countsHIV-infected adultsHIV-positive patientsHIV-1 RNAAll-cause mortalityCox proportional hazards modelsCohort of individualsHIV-positive menProportional hazards modelART-CCSex differencesCART initiationCause-specific