2015
Variations in erythropoiesis-stimulating agent administration in transfusion-dependent myelodysplastic syndromes impact response
Duong VH, Baer MR, Hendrick F, Weiss SR, Sato M, Zeidan AM, Gore SD, Davidoff AJ. Variations in erythropoiesis-stimulating agent administration in transfusion-dependent myelodysplastic syndromes impact response. Leukemia Research 2015, 39: 586-591. PMID: 25869077, PMCID: PMC4441842, DOI: 10.1016/j.leukres.2015.03.013.Peer-Reviewed Original ResearchConceptsErythropoiesis-stimulating agentsUse of darbepoetinTransfusion independenceESA initiationTransfusion dependenceMyelodysplastic syndromeESA useTransfusion-dependent MDS patientsRed blood cell transfusionNumber of weeksCox proportional hazards modelErythropoiesis-stimulating agent administrationEnd Results-MedicareWeeks of therapyBlood cell transfusionWeeks of treatmentPopulation-based studyKaplan-Meier statisticsProportional hazards modelAssociation of timingHigh response rateCell transfusionEarly administrationSurveillance EpidemiologyESA administrationPatient Cost Sharing and Receipt of Erythropoiesis-Stimulating Agents Through Medicare Part D
Davidoff AJ, Hendrick FB, Zeidan AM, Baer MR, Stuart BC, Shenolikar RA, Gore SD. Patient Cost Sharing and Receipt of Erythropoiesis-Stimulating Agents Through Medicare Part D. JCO Oncology Practice 2015, 11: e190-e198. PMID: 25563701, PMCID: PMC4371123, DOI: 10.1200/jop.2014.001527.Peer-Reviewed Original ResearchConceptsErythropoiesis-stimulating agentsLow-income subsidyMyelodysplastic syndromePhysician's officePart DOOP paymentsErythropoiesis stimulating agentsPart D claimsMedicare Part APatient cost sharingMedicare Part DESA useAnemia managementD claimsInjected medicationsDiagnosis codesMultivariable modelHome injectionMedicare beneficiariesPart BPatientsPocket costsPatient accessPrescription benefitsCost sharing
2012
Association Between FDA Safety Warnings, CMS Coverage Restrictions and Adherence to Guidelines for ESA Use in Patients with Myelodysplastic Syndromes
Hendrick F, Davidoff A, Zeidan A, Gore S, Baer M. Association Between FDA Safety Warnings, CMS Coverage Restrictions and Adherence to Guidelines for ESA Use in Patients with Myelodysplastic Syndromes. Blood 2012, 120: 971. DOI: 10.1182/blood.v120.21.971.971.Peer-Reviewed Original ResearchErythropoiesis stimulating agentsCMS national coverage determinationsFDA safety warningsESA useNational Coverage DeterminationMyelodysplastic syndromeESA initiationSerum EPO levelsMDS patientsUse of ESAsEPO levelsChronic renal failureOff-label indicationsProportion of patientsChemotherapy-related anemiaSpecific clinical parametersOff-label useTreatment of anemiaEnd of studySerum erythropoietin levelsLikelihood of responseLogistic regression modelsThromboembolic eventsTransfusion useAdverse events