2023
Differential impact of resilience on demoralization and depression in Parkinson disease
de Figueiredo J, Zhu B, Patel A, Kohn R, Koo B, Louis E. Differential impact of resilience on demoralization and depression in Parkinson disease. Frontiers In Psychiatry 2023, 14: 1207019. PMID: 37559912, PMCID: PMC10408307, DOI: 10.3389/fpsyt.2023.1207019.Peer-Reviewed Original Research
2022
Major Depressive Disorder in an International Multisite Wilson Disease Registry
Camarata M, Ala A, Coskun A, Deng Y, Embel V, Gonzalez-Peralta R, Maciejewski K, Patel A, Rubman S, To U, Tomlin R, Schilsky M, Zimbrean P. Major Depressive Disorder in an International Multisite Wilson Disease Registry. Journal Of The Academy Of Consultation-Liaison Psychiatry 2022, 64: 106-117. PMID: 36521682, DOI: 10.1016/j.jaclp.2022.12.001.Peer-Reviewed Original ResearchConceptsMajor depressive disorderWilson's diseaseDepressive disorderLifetime major depressive disorderMental health QOLPhysical health QoLMajor depressive episodeMental health qualityStructured psychiatric evaluationSignificant differencesCross-sectional reportsLiver testsLiver diseaseNeurological assessmentLife scoresClinical correlatesDepressive episodePsychiatric symptomsPsychiatric evaluationDisease RegistrySevere anxietyLaboratory testsLifetime historySignificant associationPatients
2020
P12 Effect of liver disease, neurological disease and mental health issues on quality of life in patients with wilson disease
Camarata M, Ala A, Maciejewski K, To U, Zimbrean P, Rubman S, Coskun A, Patel A, Wadhwa A, Apdik T, Tomlin R, Deng Y, Gonzalez-Peralta R, Schilsky M. P12 Effect of liver disease, neurological disease and mental health issues on quality of life in patients with wilson disease. Gut 2020, 69: a13-a13. DOI: 10.1136/gutjnl-2020-basl.23.Peer-Reviewed Original ResearchMental health issuesWilson's diseaseHealth issuesSeverity of liverMental health QOLPhysical health QoLReview of imagingP-QOL scoresQuality of lifeFIB4 scoreAdult patientsRegistry studyNeurological assessmentPhysical health issuesChronic diseasesOutcome measuresPatientsNeurological diseasesWD patientsQoLAssess qualityDiseaseCirrhosisSignificant differencesScoresP13 Major depressive disorder in patients with wilson’s disease: relationship with liver disease, neurological disease and quality of life
Camarata M, Ala A, Maciejewski K, To U, Zimbrean P, Rubman S, Patel A, Wadhwa A, Coskun A, Apdik T, Tomlin R, Deng Y, Schilsky M. P13 Major depressive disorder in patients with wilson’s disease: relationship with liver disease, neurological disease and quality of life. Gut 2020, 69: a13-a13. DOI: 10.1136/gutjnl-2020-basl.24.Peer-Reviewed Original ResearchMajor depressive disorderQuality of lifeMental health QOLWilson's diseaseNeurological diseasesLiver diseaseDepressive disorderFirst presentationExact testDepression symptomologySeverity of liverLifetime major depressive disorderLiver disease severityFisher's exact testPhysical health QOLSignificant differencesWilcoxon rank sum testMental health problemsRank sum testFIB4 scoreClinical featuresNeurological assessmentPHQ-9PatientsCurrent depressionFRI303 Major depressive disorder in patients with Wilson’s disease: relationship with liver disease, neurological disease and quality of life
Camarata M, Ala A, To U, Zimbrean P, Rubman S, Patel A, Wadhwa A, Maciejewski K, Song X, Deng Y, Tomlin R, Apdik T, Coskun A, Schilsky M. FRI303 Major depressive disorder in patients with Wilson’s disease: relationship with liver disease, neurological disease and quality of life. Journal Of Hepatology 2020, 73: s550-s551. DOI: 10.1016/s0168-8278(20)31573-7.Peer-Reviewed Original ResearchDeep Brain Stimulation Target Selection in Co-Morbid Essential Tremor and Parkinson’s Disease
Wadhwa A, Schaefer S, Gerrard J, Deeb W, Okun MS, Patel A. Deep Brain Stimulation Target Selection in Co-Morbid Essential Tremor and Parkinson’s Disease. Tremor And Other Hyperkinetic Movements 2020, 10: 17. PMID: 32775031, PMCID: PMC7394224, DOI: 10.5334/tohm.62.Peer-Reviewed Original ResearchConceptsDeep brain stimulationParkinson's diseaseEssential tremorHead trialsDBS targetsAction tremorSubthalamic nucleus (STN) DBSThalamus deep brain stimulationLimited evidenceDBS target selectionVentral intermediate nucleusBilateral STNPD patientsDBS treatmentEquivalent efficacyRest tremorMild improvementCurrent evidenceET patientsET tremorBrain stimulationComparative efficacyPatientsExpert consensusTremor reduction
2019
Dorsal GPi/GPe Stimulation Induced Dyskinesia in a Patient with Parkinson’s Disease
Elkouzi A, Tsuboi T, Burns M, Eisinger R, Patel A, Deeb W. Dorsal GPi/GPe Stimulation Induced Dyskinesia in a Patient with Parkinson’s Disease. Tremor And Other Hyperkinetic Movements 2019, 9 DOI: 10.5334/tohm.496.Peer-Reviewed Original ResearchStimulation-induced dyskinesiasParkinson's diseaseGPi DBSBilateral GPi DBSGPi stimulationMotor fluctuationsPD patientsTherapeutic benefitSide effectsVentral contactVolume of tissuePatientsDiseaseMore studiesDyskinesiaMotor controlDiffusion tensorSpecific tractsPotential strategyStimulationTherapyTractMRI
2017
Velopharyngeal Dystonia: An Unusual Focal Task-specific Dystonia?
Patel A, Sulica L, Frucht S. Velopharyngeal Dystonia: An Unusual Focal Task-specific Dystonia? Tremor And Other Hyperkinetic Movements 2017, 7: 365. DOI: 10.5334/tohm.353.Peer-Reviewed Original ResearchVelopharyngeal dysfunctionFocal task-specific dystoniaTask-specific dystoniaTask-specific movement disorderAnticholinergic medicationsNasal airwayAnatomical abnormalitiesMovement disordersTreatment responseUnrecognized etiologyPharyngeal musculatureDystoniaVoice disordersDysfunctionDisordersMedicationsPatientsAirwayEtiologyAbnormalitiesPalateSpeech patternsDeep Brain Stimulation Target Selection in an Advanced Parkinson’s Disease Patient with Significant Tremor and Comorbid Depression
Patel A. Deep Brain Stimulation Target Selection in an Advanced Parkinson’s Disease Patient with Significant Tremor and Comorbid Depression. Tremor And Other Hyperkinetic Movements 2017, 7: 447. DOI: 10.5334/tohm.369.Peer-Reviewed Original ResearchGlobus pallidus internaSTN stimulationDisease patientsSubthalamic nucleusParkinson's diseaseAdvanced Parkinson's disease (PD) patientsSignificant short-term improvementsAdvanced Parkinson's diseasePD motor symptomsParkinson's disease patientsShort-term improvementSignificant tremor reductionSTN-DBSMotor symptomsPD patientsRefractory tremorComorbid depressionDBS targetsPD tremorMood disordersBilateral DBSInsufficient evidencePatientsTremor reductionSignificant depressionDeep Brain Stimulation Target Selection in an Advanced Parkinson’s Disease Patient with Significant Tremor and Comorbid Depression
Patel AS. Deep Brain Stimulation Target Selection in an Advanced Parkinson’s Disease Patient with Significant Tremor and Comorbid Depression. Tremor And Other Hyperkinetic Movements 2017, 7: 447. PMID: 28428905, PMCID: PMC5395677, DOI: 10.7916/d8kd23nz.Peer-Reviewed Original ResearchGlobus pallidus internaSTN stimulationDisease patientsSubthalamic nucleusParkinson's diseaseAdvanced Parkinson's disease (PD) patientsSignificant short-term improvementsAdvanced Parkinson's diseasePD motor symptomsParkinson's disease patientsShort-term improvementSignificant tremor reductionSTN-DBSMotor symptomsPD patientsRefractory tremorComorbid depressionDBS targetsPD tremorMood disordersBilateral DBSInsufficient evidencePatientsTremor reductionSignificant depression
2015
Isolated vocal tremor as a focal phenotype of essential tremor: a retrospective case review
Patel A, Frucht SJ. Isolated vocal tremor as a focal phenotype of essential tremor: a retrospective case review. Journal Of Clinical Movement Disorders 2015, 2: 4. PMID: 26788340, PMCID: PMC4711152, DOI: 10.1186/s40734-015-0016-5.Peer-Reviewed Original ResearchVocal tremorFamily historyRetrospective case reviewCurrent diagnostic criteriaLeast mild improvementSodium oxybateSymptom onsetCommon medicationsInitial visitRetrospective reviewTremor improvementClinical syndromeCommon manifestationPrimary diagnosisClinical trialsAction tremorMild improvementVoice disturbanceCommon conditionLimb tremorDiagnostic criteriaAverage ageLower limbsPatientsAlcohol consumption