2007
δ‐, but not µ‐, opioid receptor stabilizes K+ homeostasis by reducing Ca2+ influx in the cortex during acute hypoxia
Chao D, Bazzy‐Asaad A, Balboni G, Xia Y. δ‐, but not µ‐, opioid receptor stabilizes K+ homeostasis by reducing Ca2+ influx in the cortex during acute hypoxia. Journal Of Cellular Physiology 2007, 212: 60-67. PMID: 17373650, DOI: 10.1002/jcp.21000.Peer-Reviewed Original ResearchConceptsMicro-opioid receptorOxygen-glucose deprivationOpioid receptorsDelta-opioid receptor activationHypoxic/ischemic stressPresence of paxillineHypoxia-induced increaseH-Dmt-TicDOR activityDOR antagonistDOR agonistsCortical slicesAcute hypoxiaMOR agonistsChannel blockersDOR effectsIschemic stressDerangementReceptor activationCortexDADLEReceptorsUnderlying mechanismChannel activityAgonists
2001
Chronic hypoxia modulates diaphragm function in the developing rat
Kass LJ, Bazzy AR. Chronic hypoxia modulates diaphragm function in the developing rat. Journal Of Applied Physiology 2001, 90: 2325-2329. PMID: 11356799, DOI: 10.1152/jappl.2001.90.6.2325.Peer-Reviewed Original ResearchConceptsOne-half relaxation timeNeuromuscular transmissionNerve stimulationChronic hypoxiaContraction timePhrenic nerve-hemidiaphragm preparationAge-matched controlsLower specific forceHypoxic diaphragmDiaphragm functionHemidiaphragm preparationHypoxic ratsHypoxic groupSpecific forceContractile propertiesControl groupRat diaphragmMaturation of mechanismsRatsGreater decreaseStimulationHypoxiaDiaphragmHypoxicDelays maturation