2024
The Impact of Obesity on the Prevalence and Complications of Perianal Fistulas of Crohn’s Disease
Youn J, Hsia K, Khadilkar S, Zeina T, Rai P, Rastogi A, Hussani S, Spence S, Adavelly P, Yanes J, Kotlier J, Sweigart B, Levy A, Friedman S. The Impact of Obesity on the Prevalence and Complications of Perianal Fistulas of Crohn’s Disease. Digestive Diseases And Sciences 2024, 1-10. PMID: 39548039, DOI: 10.1007/s10620-024-08729-7.Peer-Reviewed Original ResearchPerianal fistulasPerianal surgeryImpact of obesityComplex fistulasCrohn's perianal fistulasFecal diversionCrohn's diseaseInflammatory bowel diseaseMedian timeBMI categoriesBackgroundThe incidence of obesityHistory of perianal fistulaIncreasing BMI categoryTertiary care centerPerianal fistula surgeryIncidence of obesityRates of obesityCross-sectional studyFistula surgeryAnal surgeryNo significant differenceBackgroundThe incidenceCD patientsFistulaMaximum BMITHE IMPACT OF OBESITY ON THE PREVALENCE AND SEVERITY OF PERIANAL COMPLICATIONS OF CROHN'S DISEASE
Youn J, Hsia K, Khadilkar S, Zeina T, Rai P, Rastogi A, Adavelly P, Hussani S, Yanes J, Kotlier J, Spence S, Levy A, Friedman S. THE IMPACT OF OBESITY ON THE PREVALENCE AND SEVERITY OF PERIANAL COMPLICATIONS OF CROHN'S DISEASE. Inflammatory Bowel Diseases 2024, 30: s28-s28. DOI: 10.1093/ibd/izae020.064.Peer-Reviewed Original ResearchPrevalence of perianal diseaseSeverity of perianal diseaseBody mass indexInflammatory bowel diseasePerianal surgeryPerianal diseasePerianal fistula surgeryImpact of obesityFecal diversionPerianal fistulasCrohn's diseaseFistula surgeryMedian timeFamily historyHistory of perianal fistulaBody mass index categoriesFamily history of inflammatory bowel diseaseHistory of inflammatory bowel diseaseMaximum body mass indexIncreasing BMI categoryAssociation of obesityNon-obese patientsPerianal fistulizing diseaseCochran-Armitage trend testTertiary care center
2023
Efficacy and Safety of Hyperbaric Oxygen Therapy in Fistulizing Crohn’s Disease
Dokmak A, Sweigart B, Orekondy N, Jangi S, Weinstock J, Hamdeh S, Kochar G, Shen B, Levy A. Efficacy and Safety of Hyperbaric Oxygen Therapy in Fistulizing Crohn’s Disease. Journal Of Clinical Gastroenterology 2023, 58: 120-130. PMID: 37682003, DOI: 10.1097/mcg.0000000000001905.Peer-Reviewed Original ResearchConceptsHyperbaric oxygen therapySystematic reviewSafety of hyperbaric oxygen therapyHyperbaric oxygen therapy sessionsFistulizing Crohn's diseaseClinical responseCochrane Handbook guidelinesRisk of biasCrohn's diseaseFistulizing CDRandomized controlled trialsWeb of ScienceOxygen therapyStudy biasMeta-analysesCochrane Library databasesMeta-regressionEffective treatment optionBenefits of hyperbaric oxygen therapyControlled trialsRegulate inflammatory pathwaysMeta-analysisInflammatory bowel diseaseIncreased tissue oxygen levelsFistula typeEFFICACY AND SAFETY OF HYPERBARIC OXYGEN THERAPY IN FISTULIZING CROHN'S DISEASE: A SYSTEMATIC REVIEW AND META-ANALYSIS
Dokmak A, Sweigart B, Orekondy N, Jangi S, Hamdeh S, Weinstock J, Kochar G, Shen B, Levy A. EFFICACY AND SAFETY OF HYPERBARIC OXYGEN THERAPY IN FISTULIZING CROHN'S DISEASE: A SYSTEMATIC REVIEW AND META-ANALYSIS. Inflammatory Bowel Diseases 2023, 29: s63-s63. DOI: 10.1093/ibd/izac247.121.Peer-Reviewed Original ResearchHyperbaric oxygen therapy sessionsHyperbaric oxygen therapyInflammatory bowel diseaseClinical responseClinical remissionRandomized controlled trialsPartial responseRectovaginal fistulaFistulizing CDResponse to HBOTCrohn's diseaseControlled trialsLow adverse event ratesSystematic reviewClinical response rateOutcome dataFistulizing Crohn's diseaseAdjunctive hyperbaric oxygen therapyClosure of fistulaMeta-analysisCochrane Library databasesAdverse event ratesCessation of drainagePotential clinical benefitCase-control study
2022
Natural History of New-onset Inflammatory Bowel Disease Among Patients With Multiple Sclerosis
Gandhi S, Zelman S, De Armas R, Hemond C, Levy A, Singh S, Korzenik J, Jangi S. Natural History of New-onset Inflammatory Bowel Disease Among Patients With Multiple Sclerosis. Inflammatory Bowel Diseases 2022, 28: 1614-1617. PMID: 35348692, PMCID: PMC9527605, DOI: 10.1093/ibd/izac053.Peer-Reviewed Original Research