2010
Minimizing the Potential for Drug Bioactivation of Drug Candidates to Success in Clinical Development
Nassar A. Minimizing the Potential for Drug Bioactivation of Drug Candidates to Success in Clinical Development. 2010, 1-24. DOI: 10.1002/9780470571224.pse111.Peer-Reviewed Original ResearchDrug candidatesIdiosyncratic drug reactionsNew drug candidatesReactive metabolitesDrug discoveryDrug bioactivationDrug-metabolizing enzymesHuman drug-metabolizing enzymesPotential toxicitySafety profileDrug reactionsClinical developmentPreclinical phaseSubtle evidenceReactionRecent effortsToxicityMetabolitesCandidates
2008
Minimizing the Potential for Drug Bioactivation of Drug Candidates to Success in Clinical Development
Nassar A. Minimizing the Potential for Drug Bioactivation of Drug Candidates to Success in Clinical Development. 2008, 283-306. DOI: 10.1002/9780470439265.ch12.Peer-Reviewed Original Research