Oligo Synthesis Resource

The Keck Oligonucleotide Synthesis facility provides high quality, timely DNA synthesis. Synthesis is carried out on our Dr. Oligo 192 and Applied Biosystems 394 synthesizers. We routinely perform a wide variety of complex specialty syntheses, emphasizing quality and efficiency.

We emphasize rapid turnaround:

Normal, unpurified, 40 nanomole DNA oligos <100-mers are typically completed in <24 hours, although we cannot guarantee this. Orders submitted after 5:00 PM may not be processed until the next business day.
Longer normal, unpurified DNA oligos may take 1-2 days more due to longer synthesis and deprotection times.
Turnaround times for specialty oligos vary but are typically 5-10 business days.
Cartridge Purification/desalting does not typically change turnaround times.
PAGE purification adds one to two weeks, depending on workload.

Completed Yale orders will be delivered by courier to your P.I.'s delivery location. Deliveries will be made in the mid-afternoon. If no delivery location for your lab has been specified, we will email you when your order is ready for pick up at 300 George St. (room 2127). Non-Yale orders are shipped via Federal Express Priority 1. The current status for each oligo can be monitored using the Check My Orders.

The Keck Oligo Synthesis Section warrants that its products shall conform to the description provided on the product’s accompanying literature or analytical data. ALL PRODUCT CLAIMS, REGARDLESS OF THEIR NATURE, MUST BE BROUGHT TO OUR ATTENTION WITHIN 60 DAYS OF DELIVERY.

Due to the highly complex, customized and experimental nature of some modified oligos, we cannot guarantee the purity and yield of all modified products. Although we will do our best to ensure that the highest quality product is achieved, THE KECK OLIGO SECTION SHALL NOT IN ANY EVENT BE LIABLE FOR INCIDENTAL, CONSEQUENTIAL OR SPECIAL DAMAGES OF ANY KIND RESULTING FROM ANY USE OR FAILURE OF THE PRODUCTS NOR SHALL ITS LIABILITY IN ANY CASE EXCEED THE PURCHASE PRICE OF THE PRODUCT.