Yale/NIDA Neuroproteomics Center Pilot Project Grants



# Year

Grant Year Principal Investigator Title University Project Title


1 2009

6 T. Biederer Associate Professor Yale U. Identification and Analysis of Protein Complexes Mediating Synapse Formation


2 2009

6
S. Chandra
Assistant Professor
Yale U.
Neuronal Substrates Required for Synapse Maintenance


3 2009

6
M. Morabito
Assistant Professor
U. Mass.
Cdk5-Dependent Post-translational Modifications of PSD-95


4 2009

6
S. Sathyanesan
Assistant Professor
Yale U.
A Proteomics and Genomics Characterization of the Choroid Plexus: Protein and Gene Regulation by Psychotropic Drugs


5 2010

7
J. Bibb
Associate Professor
U. Texas Southwestern Medical Center
Phosphoprotein Analysis of the Effects of Cocaine on NMDA Receptor Regulation


6 2010

7
J. Rinehart
Assistant Professor
Yale U.
Global MRM Atlas of the Human Kinome


7 2010

7
A.J. Robison (with E. Nestler)
Postdoctoral Fellow
Mt. Sinai School Medicine
Neuronal Subtype-Specific Effects of the Transcription Factor delta FosB on Synaptic Physiology


8 2010

7
M. Torregrossa (with J. Taylor)
Assoc. Res. Sci.
Yale U.
Identification of Proteins that are Differentially Activated by Drug Cue memory Extinction and Reconsolidation in the Amygdala and Nucleus Accumbens Using Phosphoproteomics


9 2011

8
S. Chandra
Assistant Professor
Yale U.
Phosphoinositides, Synaptic Signalling, Drug Addiction, and Neurodegeneration


10 2011

8
M. Koelle
Associate Professor
Yale U.
Proteomic Analysis of Lysine Acetylation of the Neural G Protein G alphao and Its Role in Serotonin Signalling


11 2011

8
T. McClure-Begley (with M. Picciotto)
Postdoctoral Fellow
Yale U.
Defining the nAChR Interactome


12 2011

8
S. Sathyanesan
Assistant Professor
Yale U.
Development of Cerebrospinal Fluid Markers for Neuropsychiactric Disorders


13 2012

9
R. Kitchen (with A. Nairn)
Postdoctoral Associate
Yale U.
Toward Improved Label-free Quantification of MS/MS Spectra Using Predicted Proteomes


14 2015

11
B. Carlyle (with A. Nairn)
Postdoctoral Associate
Yale U.
Assessing Proteomic Differences Between the Two Types of Major Cell Types of the Striatum


15 2015

11
A. Koleske
Professor
Yale U.
Mechanisms of Cocaine-Induced Dendritic Spine Refinement and Plasticity


16 2015

11
J. Uys (with P. Kalivas)
Assistant Professor
Medical U. South Carolina Quantitative Proteomic Analysis of S-Glutathionylated Proteins after Cocaine-Induced Reinstatement


17 2015

11
J. Xu (with P. Lombroso)
Assoc. Res. Sci.
Yale U.
Post-Translational Modification of STEP61 by BDNF Signalling: Implications in Drug Abuse


18 2016

12
T. Cijsouw (with T. Biederer)
Postdoctoral Scholar
Tufts U.
Mapping the Proteome of the Synaptic cleft Through Peroxidase-Based Reporter Proteins


19 2016

12
R. Logan
Assistant Professor
U. Pittsburgh
Identifying Circadian Regulated Proteins in Specific Cell Types of the Nucleus Accumbens involved in Cocaine Reward


20 2016

12
M. Miller (with M. Picciotto)
Postdoctoral Associate
Yale U.
A Systematic Evaluation of High-Affinity α4β2 Nicotinic Acetylcholine Receptor Phosphorylation
21 2017 12 M. Monsey (with J. Taylor) Postdoctoral Associate Yale U. Profiling the neuronal proteome of the lateral amygdala following cocaine-cue memory retrieval and systemic garcinol administration
22 2017 12 R. Taugher Postdoctoral Fellow U. Iowa Role of ASIC1A in regulating the NAc proteome in both the drug naïve and cocaine withdrawn states
23 2017 12 E. Yan Professor Yale U. Role of dimerization in modulating sensitivity and dynamic range of ligand sensing in family CG protein coupled receptors
24 2018 13 L. Devi and D. Schechtman Professor and Assoc. Professor Mt. Sinai School Medicine and U. Sao Paulo, Brazil Identification of Protein Kinase C Targets Leading to Opioid Tolerance
25 2018 13 D. Kiraly Assistant Professor
Mt. Sinai School Medicine Characterization of Proteomic Changes in the Nucleus Accumbens in Response to Chronic Granulocyte-colony Stimulating Factor and Cocaine
26 2018 13 M. Girgenti Postdoctoral Associate  Yale U. Post Mortem Proteomic Characterization of Human Subgenual Prefrontal Cortex in Tobacco Abuse and PTSD
27 2018 13 M. Wolf and A. Li Professor and Postdoctoral Associate Chicago Medical School and Behavioral Neuroscience Branch, NIDA Projection-specific Proteomics in Striatum and Its Glutamatergic Afferents in Incubation of Craving to Psychostimulants (Cocaine and Methamphetamine)