Buqu Hu

2026

• EGFR-co-amplified lncRNA ELDR drives glioblastoma tumorigenicity by enhancing BMI1 activity

  Yu X, Wu R, Huang T, Tiek D, Walker M, He Q, Horbinski C, Hu B, Cheng S. EGFR-co-amplified lncRNA ELDR drives glioblastoma tumorigenicity by enhancing BMI1 activity. Neuro-Oncology 2026, noag213. PMID: 42691209, DOI: 10.1093/neuonc/noag213.

  Peer-Reviewed Original Research

• Correction: Neuropilin-1 promotes human glioma progression through potentiating the activity of the HGF/SF autocrine pathway

  Hu B, Guo P, Bar-Joseph I, Imanishi Y, Jarzynka M, Bogler O, Mikkelsen T, Hirose T, Nishikawa R, Cheng S. Correction: Neuropilin-1 promotes human glioma progression through potentiating the activity of the HGF/SF autocrine pathway. Oncogene 2026, 45: 3021-3022. PMID: 42393289, DOI: 10.1038/s41388-026-03882-x.

  Commentaries, Editorials and Letters

• Stepwise Protocol for Alternative Splicing Analysis in Single-Cell SMART-Seq2 RNA-Seq Data

  Walker M, Hu B, Cheng S, Song X. Stepwise Protocol for Alternative Splicing Analysis in Single-Cell SMART-Seq2 RNA-Seq Data. Bio-protocol 2026, 16: e5735. PMID: 42367213, PMCID: PMC13293989, DOI: 10.21769/bioprotoc.5735.

  Peer-Reviewed Original Research

  Citations

• Staphylococcus aureus superantigens drive a concentration-dependent neutrophilic or eosinophilic pulmonary inflammation in mouse models of cystic fibrosis

  Sun Y, Hu B, Harris Z, Stanley G, Sherchand S, Adhikari R, Aman J, Zhang X, Koff J, Rajagopalan G. Staphylococcus aureus superantigens drive a concentration-dependent neutrophilic or eosinophilic pulmonary inflammation in mouse models of cystic fibrosis. The Journal Of Immunology 2026, 215: vkag155. PMID: 42419962, DOI: 10.1093/jimmun/vkag155.

  Peer-Reviewed Original Research

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• Multi-omic profiling identifies TREM2+ lipid-laden macrophages as inflammatory drivers and therapeutic targets of colorectal cancer liver metastasis

  Wang P, Zhong Y, Zheng W, Xian J, Song F, Xu J, Sun Y, Cheng J, Feng H, Jiang X, Xu Y, Zhang Z, Zhou K, Guo W, Hu B, Gu L, Zhou J, Fan J, Yang X. Multi-omic profiling identifies TREM2+ lipid-laden macrophages as inflammatory drivers and therapeutic targets of colorectal cancer liver metastasis. Cancer Letters 2026, 656: 218657. PMID: 42250756, DOI: 10.1016/j.canlet.2026.218657.

  Peer-Reviewed Original Research

  Citations

  MeSH Keywords

• PPM1G‒MET axis sustains AKT signaling to drive Twist‐associated EMT and drug resistance in hepatocellular carcinoma

  Wu W, Lin S, Zhou C, Hu J, Liu K, Xu Y, Ding Z, Luo M, Hu B. PPM1G‒MET axis sustains AKT signaling to drive Twist‐associated EMT and drug resistance in hepatocellular carcinoma. View 2026 DOI: 10.1002/viw.20260024.

  Peer-Reviewed Original Research

• Global Advances in Hepatocellular Carcinoma Research and Therapy in 2025

  Hu B, Gao Q. Global Advances in Hepatocellular Carcinoma Research and Therapy in 2025. Cancer Innovation 2026, 5: e70059. PMID: 42005557, PMCID: PMC13084537, DOI: 10.1002/cai2.70059.

  Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements

  Citations

• The epidermal growth factor receptor regulates bacterial clearance in cystic fibrosis airway neutrophils

  Rasmussen L, Luthra D, Moncada-Giraldo D, Lewis C, Soto-Vazquez Y, Li Z, Hu B, Dobosh B, Stacks D, Koff J, Gaggar A, Tirouvanziam R, Margaroli C. The epidermal growth factor receptor regulates bacterial clearance in cystic fibrosis airway neutrophils. Journal Of Clinical Investigation 2026, 136: e198292. PMID: 41979898, PMCID: PMC13262706, DOI: 10.1172/jci198292.

  Peer-Reviewed Original Research

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• An EGFR co-amplified lncRNA HELDR promotes glioblastoma malignancy through KAT7-driven gene programs

  Yu X, Song X, Schäfer R, Meng Q, Tiek D, Wu R, He Q, Walker M, Cao Q, Yang R, Hu B, Cheng S. An EGFR co-amplified lncRNA HELDR promotes glioblastoma malignancy through KAT7-driven gene programs. Nature Cell Biology 2026, 28: 972-985. PMID: 41896311, PMCID: PMC13086523, DOI: 10.1038/s41556-026-01924-w.

  Peer-Reviewed Original Research

  Citations

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• Tumor-associated astrocytes augment cholesterol synthesis to support glioblastoma growth through alternatively spliced QKI isoforms

  Wu R, Yu X, Song X, He Q, Walker M, Sisbarro D, Horbinski C, Tiek D, Hu B, Zhang N, Cheng S. Tumor-associated astrocytes augment cholesterol synthesis to support glioblastoma growth through alternatively spliced QKI isoforms. Neuro-Oncology 2026, 28: 1163-1178. PMID: 41703645, PMCID: PMC13186460, DOI: 10.1093/neuonc/noag030.

  Peer-Reviewed Original Research

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