Attila Feher, MD, PhD
Assistant Professor of Medicine (Cardiovascular Medicine)Cards
About
Research
Publications
2026
Association of rheumatoid arthritis with major adverse cardiovascular events despite normal myocardial perfusion imaging
Frohlich B, Pires J, Kyrakoulis I, Wright C, Csecs I, Ahmed A, Jones X, Jacobs M, Hinchcliff M, Miller E, Feher A. Association of rheumatoid arthritis with major adverse cardiovascular events despite normal myocardial perfusion imaging. American Journal Of Preventive Cardiology 2026, 29: 101624. DOI: 10.1016/j.ajpc.2026.101624.Peer-Reviewed Original ResearchMyocardial perfusion imagingCoronary artery calcificationNormal myocardial perfusion imagingPerfusion imagingRheumatoid arthritisStress myocardial perfusion imagingPET myocardial perfusion imagingMedian Follow-UpReversible perfusion defectsDetect coronary artery calcificationHeart failure hospitalizationAssociated with higher riskMultivariate Cox regressionAdverse cardiovascular eventsNon-RA patientsAggressive preventive strategiesAssociation of rheumatoid arthritisLate revascularizationFailure hospitalizationCardiovascular-specific mortalityPerfusion defectsRA subgroupsCardiovascular comorbiditiesCardiovascular eventsAutoimmune diseasesOC.06 Elevated mortality linked to myocardial fibrosis in systemic sclerosis: a multicenter CMR study in autoimmune rheumatic diseases
Csecs I, Tysarowski M, Yit Soo C, Emokpae M, Markousis-Mavrogenis G, Bianca Dumitru R, Bissell L, Panopoulos S, Sfikakis P, Buch M, Del Galdo F, Mavrogeni S, Plein S, Hinchcliff M, Feher A. OC.06 Elevated mortality linked to myocardial fibrosis in systemic sclerosis: a multicenter CMR study in autoimmune rheumatic diseases. 2026, a7-a8. DOI: 10.1136/jsrd-2026-sswc.6.Peer-Reviewed Original ResearchIncremental Prognostic Value of Subendocardial Myocardial Flow Reserve in Patients With Normal Perfusion.
Lopez D, Brown J, Divakaran S, Huck D, Weber B, Hainer J, Carre S, Lemley M, Ramirez G, Shanbhag A, Kavanagh P, Liang J, Blankstein R, Dorbala S, Dey D, Knight S, Le V, Mason S, Wopperer S, Chareonthaitawee P, Rosamond T, Kwiecinski J, Miller R, Slipczuk L, Travin M, Alexanderson E, Carvajal-Juarez I, Packard R, Al-Mallah M, Einstein A, Feher A, Acampa W, Sanghani R, Buechel R, deKemp R, Berman D, Slomka P, Di Carli M. Incremental Prognostic Value of Subendocardial Myocardial Flow Reserve in Patients With Normal Perfusion. Circulation 2026 PMID: 42237914, DOI: 10.1161/circulationaha.125.078816.Peer-Reviewed Original ResearchIncremental prognostic valueRisk of MACEPositron emission tomographyNormal perfusionRb-82 positron emission tomographyHistory of coronary artery bypass surgeryFlow reserveLeft ventricular ejection fractionHigh riskPET metricsHigher risk of MACECoronary artery bypass surgeryVentricular ejection fractionAnnual event rateArtery bypass surgeryMyocardial flow reserveAll-Cause MortalityIncremental valuePercutaneous coronary interventionPeripheral arterial diseaseEjection fractionPrognostic utilityHeart transplantationClinical outcomesRisk stratificationBlunted Heart Rate Response to Regadenoson Predicts Cardiovascular Risk Beyond Quantitative PET Myocardial Blood Flow
Barreto J, Vashist A, Gallegos Kattan C, Stendahl J, Sadeghi M, Sposito A, Miller E, Sinusas A, Feher A, Moura F. Blunted Heart Rate Response to Regadenoson Predicts Cardiovascular Risk Beyond Quantitative PET Myocardial Blood Flow. Journal Of Nuclear Cardiology 2026, 102766. PMID: 42190937, DOI: 10.1016/j.nuclcard.2026.102766.Peer-Reviewed Original ResearchStress myocardial blood flowBlunted heart rate responseIncremental prognostic valueMyocardial flow reserveArea under the receiver-operating characteristic curveHeart rate responsePrognostic valueNet reclassification indexMyocardial blood flowNormal heart rate responseAdenosine A2A receptor agonistA2A receptor agonistReceiver-operating characteristic curveAssociated with higher CV riskBlood flowMedian Follow-UpHigh CV riskMultivariate Cox regressionPredicting cardiovascular riskRate responsePET/CT studiesPrognostic discriminationReceptor agonistsAutonomic dysfunctionClinical characteristicsImpaired Myocardial Flow Reserve and Coronary Artery Calcification Predicts Adverse Events in Patients with Autoimmune Rheumatic Diseases
Csecs I, Miller E, Hinchcliff M, Sinusas A, Feher A. Impaired Myocardial Flow Reserve and Coronary Artery Calcification Predicts Adverse Events in Patients with Autoimmune Rheumatic Diseases. EANM Innovation 2026, 3: 100191. DOI: 10.1016/j.eanmi.2026.100191.Peer-Reviewed Original ResearchB54-39 Artificial Intelligence-Enabled Coronary Artery Calcium Quantification Predicts All-Cause Mortality
Caruana D, Mojibian H, Haramati L, Feher A, Fuss C, Davis M, Bader A. B54-39 Artificial Intelligence-Enabled Coronary Artery Calcium Quantification Predicts All-Cause Mortality. American Journal Of Respiratory And Critical Care Medicine 2026, 212: aamag162.1493. DOI: 10.1093/ajrccm/aamag162.1493.Peer-Reviewed Original ResearchAll-Cause MortalityNon-contrast chest CTMultivariate logistic regression analysisLog-rank testChest CTLogistic regression analysisSevere CaCAbstract Rationale:Smoking statusKaplan-Meier survival analysisRisk of all-cause mortalityCoronary calcium scoreHigh-risk patientsChronic lung diseaseFollow-up periodCongestive heart failureCoronary artery calcificationHazard of all-cause mortalityMulticenter healthcare systemRegression analysisHazard of mortalityOverall survivalCalcium scoreAgatston scoreCAC screeningCoronary microvascular dysfunction in systemic sclerosis: insights from PET-derived myocardial flow reserve
Williams K, Emokpae M, Koyi B, Csecs I, Gunes I, Frohlich B, Sinusas A, Hinchcliff M, Feher A. Coronary microvascular dysfunction in systemic sclerosis: insights from PET-derived myocardial flow reserve. Rheumatology 2026, 65: keag215. PMID: 42024682, DOI: 10.1093/rheumatology/keag215.Peer-Reviewed Original ResearchConceptsCoronary microvascular dysfunctionMyocardial perfusion imagingPET myocardial perfusion imagingSystemic sclerosis patientsSystemic sclerosisMyocardial blood flowNon-invasive markerMicrovascular dysfunctionPET-derived MBFMarker of vascular involvementFlow reserveResting myocardial blood flowStress myocardial blood flowCalcium channel blockersYale-New Haven HospitalAssociated with vasodilationAutoimmune rheumatologic diseasesMyocardial flow reserveMMF useImmunomodulatory therapyVascular involvementChannel blockersNew Haven HospitalCardiovascular comorbiditiesProspective validationAssessing Coronary Calcium Thresholds on Attenuation-Correction CT With Myocardial Perfusion Imaging Equating to Secondary Prevention
Kyriakoulis I, Csecs I, Ahmed A, Wright C, Shanbhag A, Lemley M, Slomka P, Sinusas A, Miller E, Kokkinidis D, Feher A. Assessing Coronary Calcium Thresholds on Attenuation-Correction CT With Myocardial Perfusion Imaging Equating to Secondary Prevention. JACC Advances 2026, 5: 102732. PMID: 42000549, PMCID: PMC13098618, DOI: 10.1016/j.jacadv.2026.102732.Peer-Reviewed Original ResearchMajor adverse cardiac eventsCoronary artery calciumAtherosclerotic cardiovascular diseaseNuclear myocardial perfusion imagingMyocardial perfusion imagingMyocardial infarctionPerfusion imagingRisk of Major Adverse Cardiac EventsSecondary preventionCoronary artery calcium scoreSevere coronary artery calciumMedian Follow-UpPrimary prevention groupAdverse cardiac eventsMultivariate Cox regressionComposite of deathAtherosclerotic cardiovascular disease patientsEquivalent riskPeripheral arterial diseaseLate revascularizationAggressive managementArtery calciumAttenuation-correctedCardiac eventsSevere calcification26-A-16612-ACC PREDICTIVE ROLE OF FEATURE-TRACKING CARDIOVASCULAR MAGNETIC RESONANCE (FT-CMR) IMAGING STRAIN IN PATIENTS WITH RHEUMATOID ARTHRITIS
Csecs I, Wright C, Ahmed A, Frohlich B, Hinchcliff M, Baldassarre L, Feher A. 26-A-16612-ACC PREDICTIVE ROLE OF FEATURE-TRACKING CARDIOVASCULAR MAGNETIC RESONANCE (FT-CMR) IMAGING STRAIN IN PATIENTS WITH RHEUMATOID ARTHRITIS. Journal Of The American College Of Cardiology 2026, 87: a924. DOI: 10.1016/j.jacc.2026.02.2278.Peer-Reviewed Original Research26-A-10988-ACC BLUNTED HEART RATE RESPONSE TO REGADENOSON IS ASSOCIATED WITH HIGH RISK BEYOND PET QUANTITATIVE MYOCARDIAL BLOOD FLOW
Oliveira J, Kattan C, Vashist A, Stendahl J, Sadeghi M, Sposito A, Miller E, Sinusas A, Feher A, Moura F. 26-A-10988-ACC BLUNTED HEART RATE RESPONSE TO REGADENOSON IS ASSOCIATED WITH HIGH RISK BEYOND PET QUANTITATIVE MYOCARDIAL BLOOD FLOW. Journal Of The American College Of Cardiology 2026, 87: a936-a937. DOI: 10.1016/j.jacc.2026.02.2307.Peer-Reviewed Original Research
Academic Achievements & Community Involvement
Clinical Care
Overview
Attila Feher, MD, PhD, is a cardiologist who specializes in multimodality cardiovascular imaging, which involves analyzing pictures of the heart taken with the help of such technologies as CT scan, MRI, and nuclear imaging. He also has a special interest in preventing and managing heart disease in patients who have underlying autoimmune and rheumatologic disorders through Yale Medicine’s Cardio-Rheumatology Program.
Dr. Feher says a curiosity of human biology inspired him to study medicine, but it was during his training, when he began to interact with patients, that he knew he’d chosen the right path.
“Understanding patients’ inner feelings and helping them emotionally has always been as important to me as understanding the nature of their medical conditions,” Dr. Feher says. “I truly believe in and try to practice the instruction left by Sir William Osler, MD, one of the greatest internists of the 20th century, about keeping the patient in the center: ‘Care more particularly for the individual patient than for the special features of the disease.’”
Dr. Feher says caring for cardiology patients provides him with many opportunities to build long-lasting relationships, which are especially important in cardio-rheumatology, since autoimmune disease requires continuous monitoring. “I think meaningful interactions and paying attention to the details while keeping the patient's needs in the center are key to successfully prevent, treat, and potentially cure cardiovascular disease,” he says.
Dr. Feher’s research interests include studying the impact of autoimmune conditions on cardiovascular health, and the best ways to apply cardiovascular imaging techniques to the evaluation of coronary microvascular disease. “My clinic actively shapes my research,” he says. “I believe the bedside is the perfect place to find research topics that are relevant not only to scientists, but to patients as well.”
Clinical Specialties
News
News
- June 24, 2026
Breaking Down Silos to Understand Cardiometabolic Diseases
- May 28, 2026Source: Yale News
New Collaborative Aims to Become Hub for Women’s Health Research at Yale
- April 09, 2026
Fellow Focus in Four: Ibolya Csecs, MD, Cardiovascular Medicine
- September 10, 2024
Microvasculature Imaging Shows Promise for Peripheral Artery Disease Management
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