Rupak Datta, MD, PhD, MPH
Assistant Professor of Medicine (Infectious Diseases)Cards
Additional Titles
Assistant Hospital Epidemiologist, Hospital Epidemiology & Infection Prevention, Veterans Affairs Connecticut Healthcare System
Contact Info
Appointments
Additional Titles
Assistant Hospital Epidemiologist, Hospital Epidemiology & Infection Prevention, Veterans Affairs Connecticut Healthcare System
Contact Info
Appointments
Additional Titles
Assistant Hospital Epidemiologist, Hospital Epidemiology & Infection Prevention, Veterans Affairs Connecticut Healthcare System
Contact Info
About
Titles
Assistant Professor of Medicine (Infectious Diseases)
Positions outside Yale
Assistant Hospital Epidemiologist, Hospital Epidemiology & Infection Prevention, Veterans Affairs Connecticut Healthcare System
Biography
Dr. Datta is an Assistant Professor at the Yale School of Medicine and an Assistant Hospital Epidemiologist at the Veterans Affairs Connecticut Healthcare System. His research focuses on understanding patterns and drivers of antimicrobial use, methods to assess appropriateness, and the development and evaluation of methods to improve antimicrobial use. Beyond antimicrobial stewardship, Dr. Datta is broadly interested in the clinical epidemiology of highly antibiotic-resistant organisms and the measurement and prevention of healthcare-associated infections. His research has been supported by the NIA Imbedded Pragmatic Alzheimer’s Disease and Alzheimer’s Disease-Related Dementias Clinical Trials Collaboratory, Yale Claude D. Pepper Older Americans Independence Center, Yale Center for Clinical Investigation, and Society for Healthcare Epidemiology of America.
Appointments
Infectious Diseases
Assistant ProfessorPrimary
Other Departments & Organizations
Education & Training
- Fellowship
- Yale School of Medicine (2020)
- Resident
- Yale School of Medicine (2016)
- PhD
- University of California Irvine School of Medicine (2014)
- MD
- University of California Irvine School of Medicine (2014)
- MPH
- Yale School of Public Health (2008)
- BS
- Tufts University (2004)
Board Certifications
Internal Medicine
- Certification Organization
- AB of Internal Medicine
- Original Certification Date
- 2019
Research
Overview
Medical Research Interests
Public Health Interests
Research at a Glance
Yale Co-Authors
Publications Timeline
Research Interests
Manisha Juthani, MD
Vincent Quagliarello, MD
Louise-Marie Dembry, MD, FACP, MS, MBA, FIDSA, BS
Akiko Iwasaki, PhD
Albert Ko, MD
Richard A Martinello, MD
Infection Control
Antimicrobial Stewardship
Publications
2025
Facilitators of antibiotic decision-making in home-based primary care: a qualitative investigation
Datta R, Kiwak E, Fried T, Benjamin A, Iannone L, Krein S, Carter W, Cohen A. Facilitators of antibiotic decision-making in home-based primary care: a qualitative investigation. Infection Control And Hospital Epidemiology 2025, 46: 323-326. PMID: 39865739, DOI: 10.1017/ice.2024.241.Peer-Reviewed Original ResearchConceptsHome-based primary carePrimary careAntibiotic prescribing decisionsClinical pharmacistsPrescribing decisionsInfectious disease physiciansAntibiotic decision-makingDisease physiciansLocal initiativesCareQualitative investigationUnique challengesInfection managementDecision-makingPharmacistsPhysiciansInterventionDetection of Pneumococcal Carriage in Asymptomatic Healthcare Workers
Waghela P, Davis R, Campbell M, Datta R, Hislop M, Vega N, Wurst L, Yolda-Carr D, Couch L, Hernandez M, Grant L, Alexander-Parrish R, Arguedas A, Gessner B, Martinello R, Weinberger D, Wyllie A. Detection of Pneumococcal Carriage in Asymptomatic Healthcare Workers. Open Forum Infectious Diseases 2025, 12: ofaf008. PMID: 39917332, PMCID: PMC11800483, DOI: 10.1093/ofid/ofaf008.Peer-Reviewed Original ResearchConceptsHealthcare workersAsymptomatic healthcare workersPatient care assistantsYoung to middle-aged adultsSignificant demographic characteristicsPneumococcal carriageRegistered nursesCohort of healthcare workersCare assistantsConvenience sampleStudy participantsDetection of pneumococcal carriageRates of pneumococcal carriageMedical doctorsPediatric immunization programsDemographic characteristicsReservoir of pneumococciVaccine-targeted serotypesAdult populationHealthcareStudy populationIncreased riskPneumococcal carriage prevalenceExposure to respiratory pathogensColonized individuals
2024
Cohort study of patients with advanced cancer: outcomes associated with duration of antibiotic therapy for non-ventilator hospital-acquired pneumonia
Lee S, Benson J, Cohen A, Quagliarello V, Juthani-Mehta M, Datta R. Cohort study of patients with advanced cancer: outcomes associated with duration of antibiotic therapy for non-ventilator hospital-acquired pneumonia. Antimicrobial Stewardship & Healthcare Epidemiology 2024, 4: e48. PMID: 38655023, PMCID: PMC11036428, DOI: 10.1017/ash.2024.54.Peer-Reviewed Original ResearchConceptsNon-ventilator hospital-acquired pneumoniaAdvanced cancerPalliative care settingHospital-acquired pneumoniaCohort study of patientsCare settingsOlder adultsAdjusted oddsDuration of antibiotic therapyAssociated with reduced adjusted oddsSingle-center observational studyCohort studyProlonged antibiotic durationObservational studyStudy of patientsAntimicrobial stewardship effortsAntibiotic durationAntibiotic therapyStewardship effortsPneumoniaCancerOddsReadmissionAdultsCohortDaily Toothbrushing to Prevent Hospital-Acquired Pneumonia—Brushing Away the Risk
Datta R. Daily Toothbrushing to Prevent Hospital-Acquired Pneumonia—Brushing Away the Risk. JAMA Internal Medicine 2024, 184: 142-143. PMID: 38109108, DOI: 10.1001/jamainternmed.2023.6807.Peer-Reviewed Original ResearchDiagnostic uncertainty and decision‐making in home‐based primary care: A qualitative study of antibiotic prescribing
Datta R, Kiwak E, Fried T, Benjamin A, Iannone L, Krein S, Carter W, Cohen A. Diagnostic uncertainty and decision‐making in home‐based primary care: A qualitative study of antibiotic prescribing. Journal Of The American Geriatrics Society 2024, 72: 1468-1475. PMID: 38241465, PMCID: PMC11090732, DOI: 10.1111/jgs.18778.Peer-Reviewed Original ResearchConceptsHome-based primary carePrimary carePromote antibiotic stewardshipHome-based primary care programAntibiotic decision-makingPrimary care programsHome care settingPerspectives of cliniciansConstant comparative methodSemi-structured interviewsDeliver medical careHomebound patientsCare settingsCare programDiagnostic uncertaintyYears of experienceTheoretical saturationMedical careQualitative studyDecision-makingAntibiotic prescribingCareGrounded theoryAntibiotic stewardshipPrescribing
2023
Frontiers in antimicrobial stewardship: antimicrobial use during end-of-life care
Lee S, Datta R. Frontiers in antimicrobial stewardship: antimicrobial use during end-of-life care. Antimicrobial Stewardship & Healthcare Epidemiology 2023, 3: e164. PMID: 38028928, PMCID: PMC10644156, DOI: 10.1017/ash.2023.207.Peer-Reviewed Original ResearchCareer development in pragmatic clinical trials to improve care for people living with dementia
Gabbard J, Sadarangani T, Datta R, Fabius C, Gettel C, Douglas N, Juckett L, Kiselica A, Murali K, McCarthy E, Torke A, Callahan C. Career development in pragmatic clinical trials to improve care for people living with dementia. Journal Of The American Geriatrics Society 2023, 71: 3554-3565. PMID: 37736669, PMCID: PMC10810339, DOI: 10.1111/jgs.18599.Peer-Reviewed Original ResearchAn AI-powered patient triage platform for future viral outbreaks using COVID-19 as a disease model
Charkoftaki G, Aalizadeh R, Santos-Neto A, Tan W, Davidson E, Nikolopoulou V, Wang Y, Thompson B, Furnary T, Chen Y, Wunder E, Coppi A, Schulz W, Iwasaki A, Pierce R, Cruz C, Desir G, Kaminski N, Farhadian S, Veselkov K, Datta R, Campbell M, Thomaidis N, Ko A, Thompson D, Vasiliou V. An AI-powered patient triage platform for future viral outbreaks using COVID-19 as a disease model. Human Genomics 2023, 17: 80. PMID: 37641126, PMCID: PMC10463861, DOI: 10.1186/s40246-023-00521-4.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsCOVID-19 patientsDisease severityViral outbreaksFuture viral outbreaksLength of hospitalizationIntensive care unitWorse disease prognosisLife-threatening illnessEffective medical interventionsCOVID-19Clinical decision treeGlucuronic acid metabolitesNew potential biomarkersHospitalization lengthCare unitComorbidity dataSerotonin levelsDisease progressionHealthy controlsPatient outcomesDisease prognosisPatient transferPatientsHealthcare resourcesPotential biomarkersAntimicrobial resistance in Escherichia coli and Klebsiella pneumoniae urine isolates from a national sample of home-based primary care patients with dementia
Datta R, Pirruccio G, Fried T, O’Leary J, Zullo A, Cohen A. Antimicrobial resistance in Escherichia coli and Klebsiella pneumoniae urine isolates from a national sample of home-based primary care patients with dementia. Infection Control And Hospital Epidemiology 2023, 44: 1873-1876. PMID: 37211919, PMCID: PMC10663380, DOI: 10.1017/ice.2023.98.Peer-Reviewed Original ResearchAntibiotic therapy is associated with adverse drug events among older adults with advanced cancer: A cohort study
Datta R, Han L, Doyle M, Allore H, Sanft T, Quagliarello V, Juthani-Mehta M. Antibiotic therapy is associated with adverse drug events among older adults with advanced cancer: A cohort study. Palliative Medicine 2023, 37: 793-798. PMID: 36999898, DOI: 10.1177/02692163231162889.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsAdverse drug eventsAntibiotic therapyDrug eventsAdvanced cancerOlder adultsIndex admissionPalliative chemotherapyCohort studyTertiary care centerHospitalized older adultsPalliative care providersMultidrug-resistant organismsMean ageCommon tumorsCare centerCare providersRatio of daysSolid tumorsMultivariable testingPatientsTherapyStandardized criteriaCancerMean timeAdults
Academic Achievements & Community Involvement
honor Epi Project Competition National Society Award
National AwardSociety of Healthcare Epidemiology of AmericaDetails04/20/2022United Stateshonor Janeway Society
Yale School of Medicine AwardYale School of MedicineDetails06/08/2021United Stateshonor Iva Dostanic Physician-Scientist Trainee Award
Yale School of Medicine AwardYale School of MedicineDetails05/04/2020United Stateshonor Yoshikawa-High Award for Excellence in Research
National AwardSociety for Healthcare Epidemiology of AmericaDetails10/05/2018United Stateshonor Trainee Travel Grant
National AwardIDWeekDetails07/27/2018United States
News
News
- January 06, 2025
Request for Nominations: 2025 Iva Dostanic Award
- February 23, 2024
Department of Internal Medicine Promotions and Appointments (February 2024)
- January 16, 2024
Toothbrushing and Infection Prevention: A Q&A With Rupak Datta
- December 18, 2023Source: Medpage Today
Toothbrushing Linked to Lower Risk of Hospital-Acquired Pneumonia