Publications

• Eugenol-Loaded Lipid Nanoparticles-Derived Hydrogels Ameliorate Psoriasis-like Skin Lesions by Lowering Oxidative Stress and Modulating Inflammation.Keshari R, Tharmatt A, Pillai MM, Chitkara D, Tayalia P, Banerjee R, Sen S, Srivastava R. ACS Pharmacol Transl Sci. 2024 Nov 8; 2024 Oct 22. PMID: 39539275.
• Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape.Boddu PC, Gupta AK, Roy R, De La Peña Avalos B, Olazabal-Herrero A, Neuenkirchen N, Zimmer JT, Chandhok NS, King D, Nannya Y, Ogawa S, Lin H, Simon MD, Dray E, Kupfer GM, Verma A, Neugebauer KM, Pillai MM. Mol Cell. 2024 Apr 18; 2024 Mar 22. PMID: 38521065.
• PD-1H/VISTA mediates immune evasion in acute myeloid leukemia.Kim TK, Han X, Hu Q, Vandsemb EN, Fielder CM, Hong J, Kim KW, Mason EF, Plowman RS, Wang J, Wang Q, Zhang JP, Badri T, Sanmamed MF, Zheng L, Zhang T, Alawa J, Lee SW, Zeidan AM, Halene S, Pillai MM, Chandhok NS, Lu J, Xu ML, Gore SD, Chen L. J Clin Invest. 2024 Feb 1; 2024 Feb 1. PMID: 38060328.
• The FANCI/FANCD2 complex links DNA damage response to R-loop regulation through SRSF1-mediated mRNA export.Olazabal-Herrero A, He B, Kwon Y, Gupta AK, Dutta A, Huang Y, Boddu P, Liang Z, Liang F, Teng Y, Lan L, Chen X, Pei H, Pillai MM, Sung P, Kupfer GM. Cell Rep. 2024 Jan 23; 2024 Jan 1. PMID: 38165804.
• Acellular scaffold-based approach for in situ genetic engineering of host T-cells in solid tumor immunotherapy.Dandia HY, Pillai MM, Sharma D, Suvarna M, Dalal N, Madhok A, Ingle A, Chiplunkar SV, Galande S, Tayalia P. Mil Med Res. 2024 Jan 4; 2024 Jan 4. PMID: 38173045.
• Tetrahydrobiopterin from cyanide-degrading bacterium Bacillus pumilus strain SVD06 induces apoptosis in human lung adenocarcinoma cell (A549).Mahendran R, Selvaraj SP, Dhanapal AR, Sarasa SB, Mathias BM, Thankappan B, Femil Selta DR, Naveen P, Poorani R, Sundhar N, Pillai MM, Selvakumar R, Huang CY, Eswaran R, Angayarkanni J. Biotechnol Appl Biochem. 2023 Dec; 2023 Sep 20. PMID: 37731306.
• Bilayered skin substitute incorporating rutin nanoparticles for antioxidant, anti-inflammatory, and anti-fibrotic effect.Saha R, Patkar S, Pillai MM, Tayalia P. Biomater Adv. 2023 Jul; 2023 Apr 19. PMID: 37119696.
• Transcription elongation defects link oncogenic splicing factor mutations to targetable alterations in chromatin landscape.Boddu PC, Gupta A, Roy R, De La Pena Avalos B, Herrero AO, Neuenkirchen N, Zimmer J, Chandhok N, King D, Nannya Y, Ogawa S, Lin H, Simon M, Dray E, Kupfer G, Verma AK, Neugebauer KM, Pillai MM. bioRxiv. 2023 Feb 26; 2023 Feb 26. PMID: 36891287.
• Two-photon polymerization based reusable master template to fabricate polymer microneedles for drug delivery.Pillai MM, Ajesh S, Tayalia P. MethodsX. 2023; 2023 Jan 22. PMID: 36793674.
• Rationally designed inhibitors of the Musashi protein-RNA interaction by hotspot mimicry.Bai N, Adeshina Y, Bychkov I, Xia Y, Gowthaman R, Miller SA, Gupta AK, Johnson DK, Lan L, Golemis EA, Makhov PB, Xu L, Pillai MM, Boumber Y, Karanicolas J. Res Sq. 2023 Jan 10; 2023 Jan 10. PMID: 36711552.
• Rationally designed inhibitors of the Musashi protein-RNA interaction by hotspot mimicry.Bai N, Adeshina Y, Bychkov I, Xia Y, Gowthaman R, Miller SA, Gupta AK, Johnson DK, Lan L, Golemis EA, Makhov PB, Xu L, Pillai MM, Boumber Y, Karanicolas J. bioRxiv. 2023 Jan 10; 2023 Jan 10. PMID: 36711508.
• Activation of targetable inflammatory immune signaling is seen in myelodysplastic syndromes with SF3B1 mutations.Choudhary GS, Pellagatti A, Agianian B, Smith MA, Bhagat TD, Gordon-Mitchell S, Sahu S, Pandey S, Shah N, Aluri S, Aggarwal R, Aminov S, Schwartz L, Steeples V, Booher RN, Ramachandra M, Samson M, Carbajal M, Pradhan K, Bowman TV, Pillai MM, Will B, Wickrema A, Shastri A, Bradley RK, Martell RE, Steidl UG, Gavathiotis E, Boultwood J, Starczynowski DT, Verma A. Elife. 2022 Aug 30; 2022 Aug 30. PMID: 36040792.
• Integrative genome-wide analysis reveals EIF3A as a key downstream regulator of translational repressor protein Musashi 2 (MSI2).Karmakar S, Ramirez O, Paul KV, Gupta AK, Kumari V, Botti V, de Los Mozos IR, Neuenkirchen N, Ross RJ, Karanicolas J, Neugebauer KM, Pillai MM. NAR Cancer. 2022 Jun; 2022 May 2. PMID: 35528200.
• Novel combination of bioactive agents in bilayered dermal patches provides superior wound healing.Pillai MM, Dandia H, Checker R, Rokade S, Sharma D, Tayalia P. Nanomedicine. 2022 Feb; 2021 Nov 26. PMID: 34838992.
• A bilayered skin substitute developed using an eggshell membrane crosslinked gelatin-chitosan cryogel.Saha R, Patkar S, Maniar D, Pillai MM, Tayalia P. Biomater Sci. 2021 Nov 23; 2021 Nov 23. PMID: 34698739.
• Generation of scalable cancer models by combining AAV-intron-trap, CRISPR/Cas9, and inducible Cre-recombinase.Boddu PC, Gupta AK, Kim JS, Neugebauer KM, Waldman T, Pillai MM. Commun Biol. 2021 Oct 13; 2021 Oct 13. PMID: 34645977.
• Mesoporous Mn-doped hydroxyapatite nanorods obtained via pyridinium chloride enabled microwave-assisted synthesis by utilizing Donax variabilis seashells for implant applications.Karunakaran G, Cho EB, Thirumurugan K, Kumar GS, Kolesnikov E, Boobalan S, Janarthanan G, Pillai MM, Rajendran S. Mater Sci Eng C Mater Biol Appl. 2021 Jul; 2021 May 6. PMID: 34082971.
• Dual antimicrobial and anticancer activity of a novel synthetic α-helical antimicrobial peptide.Thankappan B, Sivakumar J, Asokan S, Ramasamy M, Pillai MM, Selvakumar R, Angayarkanni J. Eur J Pharm Sci. 2021 Jun 1; 2021 Mar 4. PMID: 33677023.
• Challenges in the Evaluation and Management of Toxicities Arising From Immune Checkpoint Inhibitor Therapy for Patients With Myeloid Malignancies.Shallis RM, Bewersdorf JP, Swoboda DM, Wei W, Gowda L, Prebet T, Halene S, Pillai MM, Parker T, Neparidze N, Podoltsev NA, Seropian S, Sallman DA, Gore SD, Zeidan AM. Clin Lymphoma Myeloma Leuk. 2021 May; 2021 Jan 12. PMID: 33551344.
• Symbiotic culture of nanocellulose pellicle: A potential matrix for 3D bioprinting.Pillai MM, Tran HN, Sathishkumar G, Manimekalai K, Yoon J, Lim D, Noh I, Bhattacharyya A. Mater Sci Eng C Mater Biol Appl. 2021 Feb; 2020 Sep 28. PMID: 33321616.
• Correction: Three-dimensional directional nerve guide conduits fabricated by dopamine-functionalized conductive carbon nanofibre-based nanocomposite ink printing.Houshyar S, Pillai MM, Saha T, Sathish-Kumar G, Dekiwadia C, Sarker SR, Sivasubramanian R, Shanks RA, Bhattacharyya A. RSC Adv. 2020 Dec 9; 2020 Dec 10. PMID: 35532429.
• Three-dimensional directional nerve guide conduits fabricated by dopamine-functionalized conductive carbon nanofibre-based nanocomposite ink printing.Houshyar S, Pillai MM, Saha T, Sathish-Kumar G, Dekiwadia C, Sarker SR, Sivasubramanian R, Shanks RA, Bhattacharyya A. RSC Adv. 2020 Nov 2; 2020 Nov 9. PMID: 35520827.
• Multi-Omics Investigation of Innate Navitoclax Resistance in Triple-Negative Breast Cancer Cells.Marczyk M, Patwardhan GA, Zhao J, Qu R, Li X, Wali VB, Gupta AK, Pillai MM, Kluger Y, Yan Q, Hatzis C, Pusztai L, Gunasekharan V. Cancers (Basel). 2020 Sep 8; 2020 Sep 8. PMID: 32911681.
• Clinical outcomes and characteristics of patients with TP53-mutated acute myeloid leukemia or myelodysplastic syndromes: a single center experience.Bewersdorf JP, Shallis RM, Gowda L, Wei W, Hager K, Isufi I, Kim TK, Pillai MM, Seropian S, Podoltsev NA, Gore SD, Siddon AJ, Zeidan AM. Leuk Lymphoma. 2020 Sep; 2020 May 2. PMID: 32362171.
• Nanocomposite-Coated Silk-Based Artificial Conduits: The Influence of Structures on Regeneration of the Peripheral Nerve.Pillai MM, Sathishkumar G, Houshyar S, Senthilkumar R, Quigley A, Shanthakumari S, Padhye R, Bhattacharyya A. ACS Appl Bio Mater. 2020 Jul 20; 2020 Jun 8. PMID: 35025444.
• Effect of nanocomposite coating and biomolecule functionalization on silk fibroin based conducting 3D braided scaffolds for peripheral nerve tissue engineering.Pillai MM, Kumar GS, Houshyar S, Padhye R, Bhattacharyya A. Nanomedicine. 2020 Feb; 2019 Nov 25. PMID: 31778808.
• Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.Kim JS, He X, Liu J, Duan Z, Kim T, Gerard J, Kim B, Pillai MM, Lane WS, Noble WS, Budnik B, Waldman T. J Biol Chem. 2019 May 31; 2019 Apr 22. PMID: 31010829.
• Ascorbic Acid-Assisted Microwave Synthesis of Mesoporous Ag-Doped Hydroxyapatite Nanorods from Biowaste Seashells for Implant Applications.Karunakaran G, Cho EB, Kumar GS, Kolesnikov E, Janarthanan G, Pillai MM, Rajendran S, Boobalan S, Gorshenkov MV, Kuznetsov D. ACS Appl Bio Mater. 2019 May 20; 2019 May 2. PMID: 35030667.
• Degenerate minigene library analysis enables identification of altered branch point utilization by mutant splicing factor 3B1 (SF3B1).Gupta AK, Murthy T, Paul KV, Ramirez O, Fisher JB, Rao S, Rosenberg AB, Seelig G, Minella AC, Pillai MM. Nucleic Acids Res. 2019 Jan 25. PMID: 30462273.
• The Development and Use of Scalable Systems for Studying Aberrant Splicing in SF3B1-Mutant CLL.Murthy T, Paul KV, Minella AC, Pillai MM. Methods Mol Biol. 2019. PMID: 30350199.
• Carbon nanofiber amalgamated 3D poly-ε-caprolactone scaffold functionalized porous-nanoarchitectures for human meniscal tissue engineering: In vitro and in vivo biocompatibility studies.Gopinathan J, Pillai MM, Shanthakumari S, Gnanapoongothai S, Dinakar Rai BK, Santosh Sahanand K, Selvakumar R, Bhattacharyya A. Nanomedicine. 2018 Oct; 2018 Aug 4. PMID: 30081102.
• Cyclin-dependent kinase 1 (CDK1) and CDK2 have opposing roles in regulating interactions of splicing factor 3B1 with chromatin.Murthy T, Bluemn T, Gupta AK, Reimer M Jr, Rao S, Pillai MM, Minella AC. J Biol Chem. 2018 Jun 29; 2018 May 15. PMID: 29764937.
• Human Knee Meniscus Regeneration Strategies: a Review on Recent Advances.Pillai MM, Gopinathan J, Selvakumar R, Bhattacharyya A. Curr Osteoporos Rep. 2018 Jun. PMID: 29663192.
• Tissue engineering of human knee meniscus using functionalized and reinforced silk-polyvinyl alcohol composite three-dimensional scaffolds: Understanding the in vitro and in vivo behavior.Pillai MM, Gopinathan J, Senthil Kumar R, Sathish Kumar G, Shanthakumari S, Sahanand KS, Bhattacharyya A, Selvakumar R. J Biomed Mater Res A. 2018 Jun; 2018 Mar 13. PMID: 29460414.
• Alternative Polyadenylation of PRELID1 Regulates Mitochondrial ROS Signaling and Cancer Outcomes.Gillen AE, Brechbuhl HM, Yamamoto TM, Kline E, Pillai MM, Hesselberth JR, Kabos P. Mol Cancer Res. 2017 Dec; 2017 Sep 14. PMID: 28912168.
• Synergistic effect of electrical conductivity and biomolecules on human meniscal cell attachment, growth, and proliferation in poly-ε-caprolactone nanocomposite scaffolds.Gopinathan J, Pillai MM, Sahanand KS, Rai BKD, Selvakumar R, Bhattacharyya A. Biomed Mater. 2017 Oct 3; 2017 Oct 3. PMID: 28703122.
• Fibroblast Subtypes Regulate Responsiveness of Luminal Breast Cancer to Estrogen.Brechbuhl HM, Finlay-Schultz J, Yamamoto TM, Gillen AE, Cittelly DM, Tan AC, Sams SB, Pillai MM, Elias AD, Robinson WA, Sartorius CA, Kabos P. Clin Cancer Res. 2017 Apr 1; 2016 Oct 4. PMID: 27702820.
• Cancer-associated SF3B1 mutants recognize otherwise inaccessible cryptic 3' splice sites within RNA secondary structures.Kesarwani AK, Ramirez O, Gupta AK, Yang X, Murthy T, Minella AC, Pillai MM. Oncogene. 2017 Feb 23; 2016 Aug 15. PMID: 27524419.
• An in vitro 3D model using collagen coated gelatin nanofibers for studying breast cancer metastasis.Janani G, Pillai MM, Selvakumar R, Bhattacharyya A, Sabarinath C. Biofabrication. 2017 Feb 7; 2017 Feb 7. PMID: 28000609.
• E2F-2 Promotes Nuclear Condensation and Enucleation of Terminally Differentiated Erythroblasts.Swartz KL, Wood SN, Murthy T, Ramirez O, Qin G, Pillai MM, Rao S, Minella AC. Mol Cell Biol. 2017 Jan 1; 2016 Dec 19. PMID: 27795297.
• Silk-PVA Hybrid Nanofibrous Scaffolds for Enhanced Primary Human Meniscal Cell Proliferation.Pillai MM, Gopinathan J, Indumathi B, Manjoosha YR, Santosh Sahanand K, Dinakar Rai BK, Selvakumar R, Bhattacharyya A. J Membr Biol. 2016 Dec; 2016 Oct 11. PMID: 27730256.
• A combination of biomolecules enhances expression of E-cadherin and peroxisome proliferator-activated receptor gene leading to increased cell proliferation in primary human meniscal cells: an in vitro study.Pillai MM, Elakkiya V, Gopinathan J, Sabarinath C, Shanthakumari S, Sahanand KS, Dinakar Rai BK, Bhattacharyya A, Selvakumar R. Cytotechnology. 2016 Oct; 2015 Oct 28. PMID: 26511364.
• Impact of silk fibroin-based scaffold structures on human osteoblast MG63 cell attachment and proliferation.Varkey A, Venugopal E, Sugumaran P, Janarthanan G, Pillai MM, Rajendran S, Bhattacharyya A. Int J Nanomedicine. 2015; 2015 Oct 1. PMID: 26491306.
• HITS-CLIP reveals key regulators of nuclear receptor signaling in breast cancer.Pillai MM, Gillen AE, Yamamoto TM, Kline E, Brown J, Flory K, Hesselberth JR, Kabos P. Breast Cancer Res Treat. 2014 Jul; 2014 Jun 7. PMID: 24906430.
• Genome-wide analysis of miRNA-mRNA interactions in marrow stromal cells.Balakrishnan I, Yang X, Brown J, Ramakrishnan A, Torok-Storb B, Kabos P, Hesselberth JR, Pillai MM. Stem Cells. 2014 Mar. PMID: 24038734.
• Primary marrow-derived stromal cells: isolation and manipulation.Ramakrishnan A, Torok-Storb B, Pillai MM. Methods Mol Biol. 2013. PMID: 23959984.
• Detection of methicillin resistance in Staphylococcus aureus by polymerase chain reaction and conventional methods: a comparative study.Pillai MM, Latha R, Sarkar G. J Lab Physicians. 2012 Jul. PMID: 23441000.
• Marrow Stromal Cell Infusion Rescues Hematopoiesis in Lethally Irradiated Mice despite Rapid Clearance after Infusion.Yang X, Balakrishnan I, Torok-Storb B, Pillai MM. Adv Hematol. 2012; 2012 Feb 16. PMID: 22400029.
• MiR-886-3p down regulates CXCL12 (SDF1) expression in human marrow stromal cells.Pillai MM, Yang X, Balakrishnan I, Bemis L, Torok-Storb B. PLoS One. 2010 Dec 13; 2010 Dec 13. PMID: 21179442.
• Inducible transgenes under the control of the hCD68 promoter identifies mouse macrophages with a distribution that differs from the F4/80 - and CSF-1R-expressing populations.Pillai MM, Hayes B, Torok-Storb B. Exp Hematol. 2009 Dec; 2009 Sep 20. PMID: 19772887.
• Protective effects of Petroselinum crispum (Mill) Nyman ex A. W. Hill leaf extract on D-galactose-induced oxidative stress in mouse brain.Vora SR, Patil RB, Pillai MM. Indian J Exp Biol. 2009 May. PMID: 19579798.
• Integration site analysis in transgenic mice by thermal asymmetric interlaced (TAIL)-PCR: segregating multiple-integrant founder lines and determining zygosity.Pillai MM, Venkataraman GM, Kosak S, Torok-Storb B. Transgenic Res. 2008 Aug; 2007 Dec 18. PMID: 18085422.
• Effect of Bacopa monniera (Linn.) on lipid peroxidation and lipofuscinogenesis in prostate gland of D-galactose induced aging mice, Mus musculus.Kalamade VI, Pillai MM, Kalamade IS. Indian J Exp Biol. 2008 Jul. PMID: 18807760.
• Monocyte-derived CXCL7 peptides in the marrow microenvironment.Pillai MM, Iwata M, Awaya N, Graf L, Torok-Storb B. Blood. 2006 May 1; 2006 Jan 3. PMID: 16391012.
• Effect of ayurvedic medicines on beta-glucuronidase activity of Brunner's glands during recovery from cysteamine induced duodenal ulcers in rats.Nadar TS, Pillai MM. Indian J Exp Biol. 1989 Nov. PMID: 2620935.
• Histopathology of liver of rats infected by cysticercus of Taenia taeniaeformis. Part I. Changes in acid and alkaline phosphatases, beta-glucuronidase and esterase activities.Varute AT, Pillai MM. Folia Histochem Cytochem (Krakow). 1974. PMID: 4442808.