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Study from authors who include several members of Yale School of Medicine reveals that a newly discovered type of immune cell found in fat tissue seems to contribute to the chronic inflammation associated with aging.

A groundbreaking study reveals that naturally occurring autoantibodies can boost or hinder cancer immunotherapy effectiveness by up to 10-fold, offering new insights into why these treatments only work for some patients. The findings appear July 23 in Nature.

Twelve Yale School of Medicine faculty members are among the leading experts in science, technology, engineering, mathematics, and medicine newly elected to the Connecticut Academy of Science and Engineering.

The study by Yale Cancer Center (YCC) researchers at Yale School of Medicine (YSM) discovered that not all CD8+ T cells are allies in a body’s fight against cancer cells. In a new study, patients living with severe melanoma who had increased levels of suppressor, regulatory CD8+ T cells had worse survival outcomes.

Researchers say the new CAR-T cell therapy significantly reduced the number of cancerous T cells, while leaving healthy cells intact.

Yuval Kluger, who works in the broad fields of bioinformatics, machine learning, and applied mathematics to develop new approaches for analyzing large biological data sets, was recently appointed the Anthony N. Brady Professor of Pathology.

Kluger works in the broad fields of bioinformatics, machine learning, and applied mathematics to develop approaches for analyzing large biological data sets.

Aged bone marrow promotes the expansion of arterial smooth muscle cells and exacerbates the build-up of fatty deposits in artery walls, a new Yale study found.

Chronic inflammation, one of the major hallmarks of aging, is thought to be partly caused by senescent cells that may accumulate in older individuals. Now, Yale researchers have received a grant from the National Institutes of Health (NIH) Common Fund’s Cellular Senescence Network Program (SenNet) to study these specialized cells.