Publications

2026

Patronin promotes formation of dynamic microtubule seeds in vivo
Shen Y, Weiner A, Thyagarajan P, Feng C, Rolls M. Patronin promotes formation of dynamic microtubule seeds in vivo. Journal Of Cell Science 2026, 139: jcs264778. PMID: 42253036, PMCID: PMC13384428, DOI: 10.1242/jcs.264778.
Peer-Reviewed Original Research
MeSH Keywords

2025

A positive feedback loop promotes the active internal state of the C. elegans egg-laying circuit
Prashad S, Davison C, Hammarlund M, Koelle M. A positive feedback loop promotes the active internal state of the C. elegans egg-laying circuit. Current Biology 2025, 35: 5521-5533.e6. PMID: 41172997, PMCID: PMC12614779, DOI: 10.1016/j.cub.2025.10.005.
Peer-Reviewed Original Research
MeSH Keywords
CellSpliceNet for Interpretable Multimodal Modeling of Alternative Splicing Across Neurons in C. elegans
Krishnaswamy S, Afrasiyabi A, Kovalic J, Liu C, Castro E, Weinreb A, Varol E, Miller D, Hammarlund M. CellSpliceNet for Interpretable Multimodal Modeling of Alternative Splicing Across Neurons in C. elegans. 2025 DOI: 10.21203/rs.3.rs-7609872/v1.
Peer-Reviewed Original Research
Alternative splicing across the C. elegans nervous system
Varol E, Barrett A, McWhirter R, Taylor S, Courtney I, Basavaraju M, Poff A, Tipps J, Collings B, Krishnaswamy S, Miller D, Hammarlund M. Alternative splicing across the C. elegans nervous system. Nature Communications 2025, 16: 4508. PMID: 40379606, PMCID: PMC12084653, DOI: 10.1038/s41467-025-58293-5.
Peer-Reviewed Original Research
MeSH Keywords

2024

Organization of a functional glycolytic metabolon on mitochondria for metabolic efficiency
Wang H, Vant J, Zhang A, Sanchez R, Micou M, Luczak V, Whiddon Z, Carlson N, Yu S, Jabbo M, Yoon S, Abushawish A, Ghassemian M, Masubuchi T, Gan Q, Watanabe S, Griffis E, Hammarlund M, Singharoy A, Pekkurnaz G. Organization of a functional glycolytic metabolon on mitochondria for metabolic efficiency. Nature Metabolism 2024, 6: 1712-1735. PMID: 39261628, PMCID: PMC12282641, DOI: 10.1038/s42255-024-01121-9.
Peer-Reviewed Original Research
MeSH Keywords
Polarized localization of kinesin-1 and RIC-7 drives axonal mitochondria anterograde transport
Ding C, Sharif B, Swaim G, Hao H, Yogev S, Watanabe S, Hammarlund M. Polarized localization of kinesin-1 and RIC-7 drives axonal mitochondria anterograde transport. Journal Of Cell Biology 2024, 223: e202305105. PMID: 38470363, PMCID: PMC10932739, DOI: 10.1083/jcb.202305105.
Peer-Reviewed Original Research
MeSH Keywords
Local and dynamic regulation of neuronal glycolysis in vivo
Wolfe A, Koberstein J, Smith C, Stewart M, Gonzalez I, Hammarlund M, Hyman A, Stork P, Colón-Ramos D. Local and dynamic regulation of neuronal glycolysis in vivo. Proceedings Of The National Academy Of Sciences Of The United States Of America 2024, 121: e2314699121. PMID: 38198527, PMCID: PMC10801914, DOI: 10.1073/pnas.2314699121.
Peer-Reviewed Original Research
MeSH Keywords

2023

The neuropeptidergic connectome of C. elegans
Ripoll-Sánchez L, Watteyne J, Sun H, Fernandez R, Taylor S, Bentley B, Hammarlund M, Miller D, Hobert O, Beets I, Vértes P, Schafer W. The neuropeptidergic connectome of C. elegans. Neuron 2023, 111: 3570-3589.e5. PMID: 37935195, PMCID: PMC7615469, DOI: 10.1016/j.neuron.2023.09.043.
Peer-Reviewed Original Research
MeSH Keywords
A kinesin-1 adaptor complex controls bimodal slow axonal transport of spectrin in Caenorhabditis elegans
Glomb O, Swaim G, LLancao P, Lovejoy C, Park J, Cason S, Holzbaur E, Hammarlund M, Howard J, Ferguson S, Gramlich M, Yogev S. A kinesin-1 adaptor complex controls bimodal slow axonal transport of spectrin in Caenorhabditis elegans. Developmental Cell 2023, 58: 1847-1863.e12. PMID: 37751746, PMCID: PMC10574138, DOI: 10.1016/j.devcel.2023.08.031.
Peer-Reviewed Original Research
MeSH Keywords
Structure-function analysis of ceTIR-1/hSARM1 explains the lack of Wallerian axonal degeneration in C. elegans
Khazma T, Grossman A, Guez-Haddad J, Feng C, Dabas H, Sain R, Weitman M, Zalk R, Isupov M, Hammarlund M, Hons M, Opatowsky Y. Structure-function analysis of ceTIR-1/hSARM1 explains the lack of Wallerian axonal degeneration in C. elegans. Cell Reports 2023, 42: 113026. PMID: 37635352, PMCID: PMC10675840, DOI: 10.1016/j.celrep.2023.113026.
Peer-Reviewed Original Research
MeSH Keywords

2022

Neurexin and frizzled intercept axonal transport at microtubule minus ends to control synapse formation
Balseiro-Gómez S, Park J, Yue Y, Ding C, Shao L, Ҫetinkaya S, Kuzoian C, Hammarlund M, Verhey KJ, Yogev S. Neurexin and frizzled intercept axonal transport at microtubule minus ends to control synapse formation. Developmental Cell 2022, 57: 1802-1816.e4. PMID: 35809561, PMCID: PMC9378695, DOI: 10.1016/j.devcel.2022.06.009.
Peer-Reviewed Original Research
MeSH Keywords
Microtubule polarity is instructive for many aspects of neuronal polarity
Thyagarajan P, Feng C, Lee D, Shorey M, Rolls M. Microtubule polarity is instructive for many aspects of neuronal polarity. Developmental Biology 2022, 486: 56-70. PMID: 35341730, PMCID: PMC9058238, DOI: 10.1016/j.ydbio.2022.03.009.
Peer-Reviewed Original Research
MeSH Keywords
Activation of the CaMKII-Sarm1-ASK1-p38 MAP kinase pathway protects against axon degeneration caused by loss of mitochondria
Ding C, Wu Y, Dabas H, Hammarlund M. Activation of the CaMKII-Sarm1-ASK1-p38 MAP kinase pathway protects against axon degeneration caused by loss of mitochondria. ELife 2022, 11: e73557. PMID: 35285800, PMCID: PMC8920508, DOI: 10.7554/elife.73557.
Peer-Reviewed Original Research
MeSH Keywords

2021

rab-27 acts in an intestinal pathway to inhibit axon regeneration in C. elegans
Lin-Moore AT, Oyeyemi MJ, Hammarlund M. rab-27 acts in an intestinal pathway to inhibit axon regeneration in C. elegans. PLOS Genetics 2021, 17: e1009877. PMID: 34818334, PMCID: PMC8612575, DOI: 10.1371/journal.pgen.1009877.
Peer-Reviewed Original Research
MeSH Keywords
Molecular topography of an entire nervous system
Taylor SR, Santpere G, Barrett A, Reilly MB, Xu C, Varol E, Oikonomou P, Glenwinkel L, McWhirter R, Poff A, Basavaraju M, Rafi I, Yemini E, Cook SJ, Abrams A, Vidal B, Cros C, Tavazoie S, Sestan N, Hammarlund M, Hobert O, Miller DM. Molecular topography of an entire nervous system. Cell 2021, 184: 4329-4347.e23. PMID: 34237253, PMCID: PMC8710130, DOI: 10.1016/j.cell.2021.06.023.
Peer-Reviewed Original Research
MeSH Keywords
In silico analysis of the transcriptional regulatory logic of neuronal identity specification throughout the C. elegans nervous system
Glenwinkel L, Taylor SR, Langebeck-Jensen K, Pereira L, Reilly MB, Basavaraju M, Rafi I, Yemini E, Pocock R, Sestan N, Hammarlund M, Miller DM, Hobert O. In silico analysis of the transcriptional regulatory logic of neuronal identity specification throughout the C. elegans nervous system. ELife 2021, 10: e64906. PMID: 34165430, PMCID: PMC8225391, DOI: 10.7554/elife.64906.
Peer-Reviewed Original Research
MeSH Keywords
Trim9 and Klp61F promote polymerization of new dendritic microtubules along parallel microtubules
Feng C, Cleary J, Kothe G, Stone M, Weiner A, Hertzler J, Hancock W, Rolls M. Trim9 and Klp61F promote polymerization of new dendritic microtubules along parallel microtubules. Journal Of Cell Science 2021, 134 PMID: 34096607, PMCID: PMC8214762, DOI: 10.1242/jcs.258437.
Peer-Reviewed Original Research
MeSH Keywords
A head-to-head comparison of ribodepletion and polyA selection approaches for Caenorhabditis elegans low input RNA-sequencing libraries
Barrett A, McWhirter R, Taylor SR, Miller DM, Hammarlund M. A head-to-head comparison of ribodepletion and polyA selection approaches for Caenorhabditis elegans low input RNA-sequencing libraries. G3: Genes, Genomes, Genetics 2021, 11: jkab121. PMID: 33856427, PMCID: PMC8495925, DOI: 10.1093/g3journal/jkab121.
Peer-Reviewed Original Research
MeSH Keywords

2020

A Functional Non-coding RNA Is Produced from xbp-1 mRNA
Liu X, Beaudoin JD, Davison CA, Kosmaczewski SG, Meyer BI, Giraldez AJ, Hammarlund M. A Functional Non-coding RNA Is Produced from xbp-1 mRNA. Neuron 2020, 107: 854-863.e6. PMID: 32640191, PMCID: PMC7486263, DOI: 10.1016/j.neuron.2020.06.015.
Peer-Reviewed Original Research
MeSH Keywords
Microtubule dynamics in healthy and injured neurons
Rolls M, Thyagarajan P, Feng C. Microtubule dynamics in healthy and injured neurons. Developmental Neurobiology 2020, 81: 321-332. PMID: 32291942, PMCID: PMC7572564, DOI: 10.1002/dneu.22746.
Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
MeSH Keywords
The stress-responsive gene GDPGP1/mcp-1 regulates neuronal glycogen metabolism and survival
Schulz A, Sekine Y, Oyeyemi MJ, Abrams AJ, Basavaraju M, Han SM, Groth M, Morrison H, Strittmatter SM, Hammarlund M. The stress-responsive gene GDPGP1/mcp-1 regulates neuronal glycogen metabolism and survival. Journal Of Cell Biology 2020, 219: e201807127. PMID: 31968056, PMCID: PMC7041677, DOI: 10.1083/jcb.201807127.
Peer-Reviewed Original Research
MeSH Keywords

2019

Patronin-mediated minus end growth is required for dendritic microtubule polarity
Feng C, Thyagarajan P, Shorey M, Seebold D, Weiner A, Albertson R, Rao K, Sagasti A, Goetschius D, Rolls M. Patronin-mediated minus end growth is required for dendritic microtubule polarity. Journal Of Cell Biology 2019, 218: 2309-2328. PMID: 31076454, PMCID: PMC6605808, DOI: 10.1083/jcb.201810155.
Peer-Reviewed Original Research
MeSH Keywords
Mechanisms of injury-induced axon degeneration
Ding C, Hammarlund M. Mechanisms of injury-induced axon degeneration. Current Opinion In Neurobiology 2019, 57: 171-178. PMID: 31071521, PMCID: PMC6629473, DOI: 10.1016/j.conb.2019.03.006.
Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
MeSH Keywords

2018

See All Publications

Publications

2026

Patronin promotes formation of dynamic microtubule seeds in vivo

2025

A positive feedback loop promotes the active internal state of the C. elegans egg-laying circuit

CellSpliceNet for Interpretable Multimodal Modeling of Alternative Splicing Across Neurons in C. elegans

Alternative splicing across the C. elegans nervous system

2024

Organization of a functional glycolytic metabolon on mitochondria for metabolic efficiency

Polarized localization of kinesin-1 and RIC-7 drives axonal mitochondria anterograde transport

Local and dynamic regulation of neuronal glycolysis in vivo

2023

The neuropeptidergic connectome of C. elegans

A kinesin-1 adaptor complex controls bimodal slow axonal transport of spectrin in Caenorhabditis elegans

Structure-function analysis of ceTIR-1/hSARM1 explains the lack of Wallerian axonal degeneration in C. elegans

2022

Neurexin and frizzled intercept axonal transport at microtubule minus ends to control synapse formation

Microtubule polarity is instructive for many aspects of neuronal polarity

Activation of the CaMKII-Sarm1-ASK1-p38 MAP kinase pathway protects against axon degeneration caused by loss of mitochondria

2021

rab-27 acts in an intestinal pathway to inhibit axon regeneration in C. elegans

Molecular topography of an entire nervous system

In silico analysis of the transcriptional regulatory logic of neuronal identity specification throughout the C. elegans nervous system

Trim9 and Klp61F promote polymerization of new dendritic microtubules along parallel microtubules

A head-to-head comparison of ribodepletion and polyA selection approaches for Caenorhabditis elegans low input RNA-sequencing libraries

2020

A Functional Non-coding RNA Is Produced from xbp-1 mRNA

Microtubule dynamics in healthy and injured neurons

The stress-responsive gene GDPGP1/mcp-1 regulates neuronal glycogen metabolism and survival

2019

Patronin-mediated minus end growth is required for dendritic microtubule polarity

Mechanisms of injury-induced axon degeneration

2018

Aberrant information transfer interferes with functional axon regeneration

γ-Neurexin and Frizzled Mediate Parallel Synapse Assembly Pathways Antagonized by Receptor Endocytosis