YSPH Convenes Experts to Examine Alcohol’s Role in Cancer
Chronic alcohol abuse is considered to be an important risk factor for disease worldwide. In addition, alcohol and its metabolite, acetaldehyde, are recognized as carcinogens that contribute to four percent of cancer deaths. Although scientific studies began to show this association over 100 years ago, the role of alcohol in chronic diseases such as cancer is still not well understood by the public and medical professionals. The 4th International Conference on Alcohol and Cancer was organized by Vasilis Vasiliou, PhD, the Susan Dwight Bliss Professor of Epidemiology, sponsored by the Department of Environmental Health Sciences of the Yale School of Public Health, and supported by an R13 grant from the National Institute of Alcohol Abuse and Alcoholism (NIAAA). The conference, held in Newport, R.I., brought together 75 international scholars with special interest in alcohol and/or cancer.
Breaking it Down: How the Chemistry of Digestion is Uncovering Sex-Specific Causes of Colon Cancer
A new technology called metabolomics allows researchers to explore the small chemicals formed and used during digestion as a window into the formation of diseases such as colon cancer, seeking early warning signs and potent tactics for prevention.
Digestion Could Account for Differences in Colon Cancer Among Men, Women
Although women are less likely to develop colon cancer than men, they have higher rates of right-sided colon cancer, which is linked to worse outcomes since it is close in proximity to the small intestine. Colorectal cancer results in more than 50,000 people each year, and is a leading cause of death for both sexes. While this cancer is avoidable through a healthy diet, many Americans develop this cancer each year. A new study being conducted by the Yale Cancer Center suggests that digestion differences could result in sex disparities for colon cancer, according to a press release.Source: Specialty Pharmacy Times
Can Digestive Chemistry Uncover Sex-Specific Causes of Colon Cancer?
Dr. Caroline Helen Johnson received this year’s Wendy U. and Thomas C. Naratil Pioneer Award and co-funding from the Yale Cancer Center to explore hormones and environmental factors related to metabolite production (such as sugars and amino acids) and beneficial bacteria that live in the colon as possible sources of gender difference.
Women’s Health Research at Yale funds studies on colon cancer, infections in pregnancy, and domestic violence
“Through our competitive peer review process, these three studies stood out as extremely promising opportunities to improve and even save lives,” said Dr. Carolyn M. Mazure, director of WHRY. “With these new grants, we continue to expand a broad scope of existing work to focus on questions vital to the health and well-being of millions of women, men, and children.”
The Promise and Future of Metabolomics in Public Health - A Q&A with Dr. Caroline Johnson
Caroline H. Johnson, Ph.D., an assistant professor in the Department of Environmental Health Sciences, joined the Yale School of Public Health in the summer of 2016. Her research uses mass spectrometry-based metabolomics to understand the role of metabolites (small molecules produced during metabolism) in human health.
Study: Patient’s Genetic Characteristics May Help Differentiate HER2-Low Advanced Breast Cancers and Guide Treatment Selection
In a new study led by Yale Cancer Center researchers at Yale School of Medicine, their findings revealed important differences in the genetic makeup of HER2-low advanced breast cancers — a discovery that could lead to better treatment options for patients.
Phase 3 Results Offer Hope for Patients With Myelodysplastic Syndromes
Senior author of the study and Yale Cancer Center expert Amer Zeidan , MBBS, says the results showed that imetelstat, a first-in-class telomerase inhibitor, leads to durable red blood cell transfusion independence and a significant improvement in anemia in heavily transfused lower-risk MDS patients.
Yale Cancer Center Experts Present New Research at Hematology Annual Meeting
Physicians and scientists from Yale Cancer Center, part of Yale School of Medicine, will present new research at the 65th American Society of Hematology (ASH) Annual Meeting and Exposition in San Diego, Calif., from December 9 to 12.
Yale Researchers Develop New Testing Criteria for Hereditary Stomach Cancer
Yale researchers have shown that individuals who carry a mutation in the CDH1 gene have a 30% to 40% risk of developing stomach cancer during their lifetime. Yet many people with the rare inherited condition remain unaware that they have it.
Yale scientists chosen by White House to expedite cancer research
Yale is one of three institutions that have been honored with the White House Cancer Moonshot research grant. Yale's Douglas Hanlon, PhD, research scientist in dermatology, and Richard Edelson, MD, the Anthony N. Brady Professor of Dermatology, describe their groundbreaking research, using mRNA technology to create a vaccine that targets only cancer cells.Source: WTNH News 8
YSPH alumna Margaret Mayer embraces challenge of grant management at the National Cancer Institute
This Alumni Spotlight focuses on Margaret Mayer, PhD ’19 (Chronic Disease Epidemiology), MPH ’16 (Chronic Disease Epidemiology), the program director in the Tobacco Cancer Research Branch at the National Cancer Institute.
Overdiagnosis and Preventative Screening: A Q&A With Ilana Richman
In a Q&A, Ilana Richman, MD, MHS, assistant professor of medicine (general medicine), discusses why overdiagnosis is a concern, the challenges of assessing the benefit of new screening technologies, and the risks and benefits people should weigh when considering preventative screening.
Sang Taek Kim Returns to YSM to Lead Immunotherapy Adverse Events Program
A physician scientist, Sang Taek Kim, MD, PhD, assistant professor of medicine (rheumatology), is interested in the autoimmune complications induced by cancer immunotherapy. In his new role, he serves as director of the Immunotherapy Adverse Events in Rheumatology Program.