Publications

Textbooks

Review Articles

"Impaired consciousness in epilepsy." (Lancet Neurology, 2012).

"Arousal and Consciousness in Focal Seizures" (Epilepsy Currents, 2021).

"Brain Mechanisms of Conscious Awareness: Detect, Pulse, Switch, and Wave" (Neuroscientist, 2023).

Selected Publications

Decreased but diverse activity of cortical and thalamic neurons in consciousness-impairing rodent absence seizures.McCafferty C, Gruenbaum BF, Tung R, Li JJ, Zheng X, Salvino P, Vincent P, Kratochvil Z, Ryu JH, Khalaf A, Swift K, Akbari R, Islam W, Antwi P, Johnson EA, Vitkovskiy P, Sampognaro J, Freedman IG, Kundishora A, Depaulis A, David F, Crunelli V, Sanganahalli BG, Herman P, Hyder F, Blumenfeld H. Nat Commun. 2023 Jan 10; 2023 Jan 10. PMID: 36627270.
Human visual consciousness involves large scale cortical and subcortical networks independent of task report and eye movement activity.Kronemer SI, Aksen M, Ding JZ, Ryu JH, Xin Q, Ding Z, Prince JS, Kwon H, Khalaf A, Forman S, Jin DS, Wang K, Chen K, Hu C, Agarwal A, Saberski E, Wafa SMA, Morgan OP, Wu J, Christison-Lagay KL, Hasulak N, Morrell M, Urban A, Todd Constable R, Pitts M, Mark Richardson R, Crowley MJ, Blumenfeld H. Nat Commun. 2022 Nov 29; 2022 Nov 29. PMID: 36446792.
Early cortical signals in visual stimulus detection.Kwon H, Kronemer SI, Christison-Lagay KL, Khalaf A, Li J, Ding JZ, Freedman NC, Blumenfeld H. Neuroimage. 2021 Dec 1; 2021 Sep 21. PMID: 34560270.
The pulse: transient fMRI signal increases in subcortical arousal systems during transitions in attention.Li R, Ryu JH, Vincent P, Springer M, Kluger D, Levinsohn EA, Chen Y, Chen H, Blumenfeld H. Neuroimage. 2021 May 15; 2021 Feb 27. PMID: 33647499.
A Switch and Wave of Neuronal Activity in the Cerebral Cortex During the First Second of Conscious Perception.Herman WX, Smith RE, Kronemer SI, Watsky RE, Chen WC, Gober LM, Touloumes GJ, Khosla M, Raja A, Horien CL, Morse EC, Botta KL, Hirsch LJ, Alkawadri R, Gerrard JL, Spencer DD, Blumenfeld H. Cereb Cortex. 2019 Feb 1. PMID: 29194517.
Restoring Conscious Arousal During Focal Limbic Seizures with Deep Brain Stimulation.Kundishora AJ, Gummadavelli A, Ma C, Liu M, McCafferty C, Schiff ND, Willie JT, Gross RE, Gerrard J, Blumenfeld H. Cereb Cortex. 2017 Mar 1. PMID: 26941379.
Impaired consciousness in patients with absence seizures investigated by functional MRI, EEG, and behavioural measures: a cross-sectional study.Guo JN, Kim R, Chen Y, Negishi M, Jhun S, Weiss S, Ryu JH, Bai X, Xiao W, Feeney E, Rodriguez-Fernandez J, Mistry H, Crunelli V, Crowley MJ, Mayes LC, Constable RT, Blumenfeld H. Lancet Neurol. 2016 Dec. PMID: 27839650.
Decreased subcortical cholinergic arousal in focal seizures.Motelow JE, Li W, Zhan Q, Mishra AM, Sachdev RN, Liu G, Gummadavelli A, Zayyad Z, Lee HS, Chu V, Andrews JP, Englot DJ, Herman P, Sanganahalli BG, Hyder F, Blumenfeld H. Neuron. 2015 Feb 4. PMID: 25654258.
Where fMRI and electrophysiology agree to disagree: corticothalamic and striatal activity patterns in the WAG/Rij rat.Mishra AM, Ellens DJ, Schridde U, Motelow JE, Purcaro MJ, DeSalvo MN, Enev M, Sanganahalli BG, Hyder F, Blumenfeld H. J Neurosci. 2011 Oct 19. PMID: 22016539.
Cortical and subcortical networks in human secondarily generalized tonic-clonic seizures.Blumenfeld H, Varghese GI, Purcaro MJ, Motelow JE, Enev M, McNally KA, Levin AR, Hirsch LJ, Tikofsky R, Zubal IG, Paige AL, Spencer SS. Brain. 2009 Apr; 2009 Apr 1. PMID: 19339252.
Early treatment suppresses the development of spike-wave epilepsy in a rat model.Blumenfeld H, Klein JP, Schridde U, Vestal M, Rice T, Khera DS, Bashyal C, Giblin K, Paul-Laughinghouse C, Wang F, Phadke A, Mission J, Agarwal RK, Englot DJ, Motelow J, Nersesyan H, Waxman SG, Levin AR. Epilepsia. 2008 Mar; 2007 Dec 6. PMID: 18070091.

All Publications

Decreased locus coeruleus multiunit activity in a mouse model of temporal lobe seizures with impaired consciousness.Valcarce-Aspegren M, Paszkowski P, Liu S, Wu Q, McGill S, Sieu LA, Blumenfeld H. Exp Neurol. 2025 Jul; 2025 Apr 4. PMID: 40189126.
Shared subcortical arousal systems across sensory modalities during transient modulation of attention.Khalaf A, Lopez E, Li J, Horn A, Edlow BL, Blumenfeld H. Neuroimage. 2025 May 15; 2025 Apr 16. PMID: 40250641.
Adversarial testing of global neuronal workspace and integrated information theories of consciousness.Ferrante O, Gorska-Klimowska U, Henin S, Hirschhorn R, Khalaf A, Lepauvre A, Liu L, Richter D, Vidal Y, Bonacchi N, Brown T, Sripad P, Armendariz M, Bendtz K, Ghafari T, Hetenyi D, Jeschke J, Kozma C, Mazumder DR, Montenegro S, Seedat A, Sharafeldin A, Yang S, Baillet S, Chalmers DJ, Cichy RM, Fallon F, Panagiotaropoulos TI, Blumenfeld H, de Lange FP, Devore S, Jensen O, Kreiman G, Luo H, Boly M, Dehaene S, Koch C, Tononi G, Pitts M, Mudrik L, Melloni L. Nature. 2025 Apr 30; 2025 Apr 30. PMID: 40307561.
Updated classification of epileptic seizures: Position paper of the International League Against Epilepsy.Beniczky S, Trinka E, Wirrell E, Abdulla F, Al Baradie R, Alonso Vanegas M, Auvin S, Singh MB, Blumenfeld H, Bogacz Fressola A, Caraballo R, Carreno M, Cendes F, Charway A, Cook M, Craiu D, Ezeala-Adikaibe B, Frauscher B, French J, Gule MV, Higurashi N, Ikeda A, Jansen FE, Jobst B, Kahane P, Kishk N, Khoo CS, Vinayan KP, Lagae L, Lim KS, Lizcano A, McGonigal A, Perez-Gosiengfiao KT, Ryvlin P, Specchio N, Sperling MR, Stefan H, Tatum W, Tripathi M, Yacubian EM, Wiebe S, Wilmshurst J, Zhou D, Cross JH. Epilepsia. 2025 Apr 23; 2025 Apr 23. PMID: 40264351.
The neural activity of auditory conscious perception.Christison-Lagay KL, Khalaf A, Freedman NC, Micek C, Kronemer SI, Gusso MM, Kim L, Forman S, Ding J, Aksen M, Abdel-Aty A, Kwon H, Markowitz N, Yeagle E, Espinal E, Herrero J, Bickel S, Young J, Mehta A, Wu K, Gerrard J, Damisah E, Spencer D, Blumenfeld H. Neuroimage. 2025 Mar; 2025 Jan 19. PMID: 39832539.
Automatic responsiveness testing in epilepsy with wearable technology: The ARTiE Watch.Wheeler L, Kremen V, Mersereau C, Ornelas G, Yadav T, Cormier D, Derry A, Duque Lopez A, McQuown K, Sladky V, Benjamin C, Giacino J, Worrell G, Blumenfeld H. Epilepsia. 2025 Jan; 2024 Nov 19. PMID: 39559901.
Slow and fast cortical cholinergic arousal is reduced in a mouse model of focal seizures with impaired consciousness.Sieu LA, Singla S, Liu J, Zheng X, Sharafeldin A, Chandrasekaran G, Valcarce-Aspegren M, Niknahad A, Fu I, Doilicho N, Gummadavelli A, McCafferty C, Crouse RB, Perrenoud Q, Picciotto MR, Cardin JA, Blumenfeld H. Cell Rep. 2024 Dec 24; 2024 Dec 5. PMID: 39643969.
Neuronal rhythmicity and cortical arousal in a mouse model of absence epilepsy.Khan W, Chopra S, Zheng X, Liu S, Paszkowski P, Valcarce-Aspegren M, Sieu LA, Mcgill S, Mccafferty C, Blumenfeld H. Exp Neurol. 2024 Nov; 2024 Aug 14. PMID: 39151596.
Shared subcortical arousal systems across sensory modalities during transient modulation of attention.Khalaf A, Lopez E, Li J, Horn A, Edlow BL, Blumenfeld H. bioRxiv. 2024 Oct 1; 2024 Oct 1. PMID: 39345640.
Spatiotemporal features of neurovascular (un)coupling with stimulus-induced activity and hypercapnia challenge in cerebral cortex and olfactory bulb.James S, Sanggaard S, Akif A, Mishra SK, Sanganahalli BG, Blumenfeld H, Verhagen JV, Hyder F, Herman P. J Cereb Blood Flow Metab. 2023 Nov; 2023 Jun 21. PMID: 37340791.
Mapping Lesion-Related Epilepsy to a Human Brain Network.Schaper FLWVJ, Nordberg J, Cohen AL, Lin C, Hsu J, Horn A, Ferguson MA, Siddiqi SH, Drew W, Soussand L, Winkler AM, Simó M, Bruna J, Rheims S, Guenot M, Bucci M, Nummenmaa L, Staals J, Colon AJ, Ackermans L, Bubrick EJ, Peters JM, Wu O, Rost NS, Grafman J, Blumenfeld H, Temel Y, Rouhl RPW, Joutsa J, Fox MD. JAMA Neurol. 2023 Sep 1. PMID: 37399040.
Predictive Power of Interictal Epileptiform Discharges in Fitness-to-Drive Evaluation.Krestel H, Schreier DR, Sakiri E, von Allmen A, Abukhadra Y, Nirkko A, Steinlin M, Rosenow F, Markhus R, Schneider G, Jagella C, Mathis J, Blumenfeld H. Neurology. 2023 Aug 29; 2023 Jul 6. PMID: 37414567.
Quantitative epileptiform burden and electroencephalography background features predict post-traumatic epilepsy.Chen Y, Li S, Ge W, Jing J, Chen HY, Doherty D, Herman A, Kaleem S, Ding K, Osman G, Swisher CB, Smith C, Maciel CB, Alkhachroum A, Lee JW, Dhakar MB, Gilmore EJ, Sivaraju A, Hirsch LJ, Omay SB, Blumenfeld H, Sheth KN, Struck AF, Edlow BL, Westover MB, Kim JA. J Neurol Neurosurg Psychiatry. 2023 Mar; 2022 Oct 14. PMID: 36241423.
An adversarial collaboration protocol for testing contrasting predictions of global neuronal workspace and integrated information theory.Melloni L, Mudrik L, Pitts M, Bendtz K, Ferrante O, Gorska U, Hirschhorn R, Khalaf A, Kozma C, Lepauvre A, Liu L, Mazumder D, Richter D, Zhou H, Blumenfeld H, Boly M, Chalmers DJ, Devore S, Fallon F, de Lange FP, Jensen O, Kreiman G, Luo H, Panagiotaropoulos TI, Dehaene S, Koch C, Tononi G. PLoS One. 2023; 2023 Feb 10. PMID: 36763595.
Early neural activity changes associated with stimulus detection during visual conscious perception.Khalaf A, Kronemer SI, Christison-Lagay K, Kwon H, Li J, Wu K, Blumenfeld H. Cereb Cortex. 2023 Feb 7. PMID: 35446937.
Brain Mechanisms of Conscious Awareness: Detect, Pulse, Switch, and Wave.Blumenfeld H. Neuroscientist. 2023 Feb; 2021 Oct 11. PMID: 34632846.
Decreased but diverse activity of cortical and thalamic neurons in consciousness-impairing rodent absence seizures.McCafferty C, Gruenbaum BF, Tung R, Li JJ, Zheng X, Salvino P, Vincent P, Kratochvil Z, Ryu JH, Khalaf A, Swift K, Akbari R, Islam W, Antwi P, Johnson EA, Vitkovskiy P, Sampognaro J, Freedman IG, Kundishora A, Depaulis A, David F, Crunelli V, Sanganahalli BG, Herman P, Hyder F, Blumenfeld H. Nat Commun. 2023 Jan 10; 2023 Jan 10. PMID: 36627270.
Distinct signatures of loss of consciousness in focal impaired awareness versus tonic-clonic seizures.Juan E, Górska U, Kozma C, Papantonatos C, Bugnon T, Denis C, Kremen V, Worrell G, Struck AF, Bateman LM, Merricks EM, Blumenfeld H, Tononi G, Schevon C, Boly M. Brain. 2023 Jan 5. PMID: 36383415.
Human visual consciousness involves large scale cortical and subcortical networks independent of task report and eye movement activity.Kronemer SI, Aksen M, Ding JZ, Ryu JH, Xin Q, Ding Z, Prince JS, Kwon H, Khalaf A, Forman S, Jin DS, Wang K, Chen K, Hu C, Agarwal A, Saberski E, Wafa SMA, Morgan OP, Wu J, Christison-Lagay KL, Hasulak N, Morrell M, Urban A, Todd Constable R, Pitts M, Mark Richardson R, Crowley MJ, Blumenfeld H. Nat Commun. 2022 Nov 29; 2022 Nov 29. PMID: 36446792.
More than a feeling: Scalp EEG and eye signals in conscious tactile perception.Gusso MM, Christison-Lagay KL, Zuckerman D, Chandrasekaran G, Kronemer SI, Ding JZ, Freedman NC, Nohama P, Blumenfeld H. Conscious Cogn. 2022 Oct; 2022 Sep 22. PMID: 36156359.
A machine-learning approach for predicting impaired consciousness in absence epilepsy.Springer M, Khalaf A, Vincent P, Ryu JH, Abukhadra Y, Beniczky S, Glauser T, Krestel H, Blumenfeld H. Ann Clin Transl Neurol. 2022 Oct; 2022 Sep 16. PMID: 36114696.
Evaluating consciousness and awareness during focal seizures: responsiveness testing versus recall testing.Contreras Ramirez V, Patedakis Litvinov B, Gunawardane NA, Zhao CW, Yotter C, Quraishi IH, Blumenfeld H. Epileptic Disord. 2022 Oct 1. PMID: 35904040.
Subcortical Cognition: The Fruit Below the Rind.Janacsek K, Evans TM, Kiss M, Shah L, Blumenfeld H, Ullman MT. Annu Rev Neurosci. 2022 Jul 8; 2022 Apr 6. PMID: 35385670.
Factors Predicting Outcome After Intracranial EEG Evaluation in Patients With Medically Refractory Epilepsy.Sivaraju A, Hirsch L, Gaspard N, Farooque P, Gerrard J, Xu Y, Deng Y, Damisah E, Blumenfeld H, Spencer DD. Neurology. 2022 Jul 5; 2022 May 4. PMID: 35508395.
Seizure semiology: ILAE glossary of terms and their significance.Beniczky S, Tatum WO, Blumenfeld H, Stefan H, Mani J, Maillard L, Fahoum F, Vinayan KP, Mayor LC, Vlachou M, Seeck M, Ryvlin P, Kahane P. Epileptic Disord. 2022 Jun 1. PMID: 35770761.
Thalamic activations in rat brain by fMRI during tactile (forepaw, whisker) and non-tactile (visual, olfactory) sensory stimulations.Sanganahalli BG, Thompson GJ, Parent M, Verhagen JV, Blumenfeld H, Herman P, Hyder F. PLoS One. 2022; 2022 May 6. PMID: 35522646.
Testing awareness in focal seizures: Clinical practice and interpretation of current guidelines.Contreras Ramirez V, Vaddiparti A, Blumenfeld H. Ann Clin Transl Neurol. 2022 May; 2022 Apr 29. PMID: 35485201.
Reliability of patient self-report of cognition, awareness, and consciousness during seizures.Zhao CW, Gebre R, Baykara Y, Chen W, Vitkovskiy P, Li N, Johnson M, Chen EY, Kluger D, Blumenfeld H. Ann Clin Transl Neurol. 2022 Jan; 2022 Jan 11. PMID: 35014222.
Simulated driving in the epilepsy monitoring unit: Effects of seizure type, consciousness, and motor impairment.Kumar A, Martin R, Chen W, Bauerschmidt A, Youngblood MW, Cunningham C, Si Y, Ezeani C, Kratochvil Z, Bronen J, Thomson J, Riordan K, Yoo JY, Shirka R, Manganas L, Krestel H, Hirsch LJ, Blumenfeld H. Epilepsia. 2022 Jan; 2021 Nov 24. PMID: 34816425.
Early cortical signals in visual stimulus detection.Kwon H, Kronemer SI, Christison-Lagay KL, Khalaf A, Li J, Ding JZ, Freedman NC, Blumenfeld H. Neuroimage. 2021 Dec 1; 2021 Sep 21. PMID: 34560270.
Short-term changes in cortical physiological arousal measured by electroencephalography during thalamic centromedian deep brain stimulation.Martin RA, Cukiert A, Blumenfeld H. Epilepsia. 2021 Nov; 2021 Aug 18. PMID: 34405892.
Arousal and Consciousness in Focal Seizures.Blumenfeld H. Epilepsy Curr. 2021 Oct; 2021 Oct 24. PMID: 34924835.
Cortical low-frequency power correlates with behavioral impairment in animal model of focal limbic seizures.Gummadavelli A, Martin R, Goshay D, Sieu LA, Xu J, Gruenbaum BF, McCafferty C, Gerrard JL, Blumenfeld H. Epilepsia. 2021 Aug; 2021 Jul 9. PMID: 34240747.
The pulse: transient fMRI signal increases in subcortical arousal systems during transitions in attention.Li R, Ryu JH, Vincent P, Springer M, Kluger D, Levinsohn EA, Chen Y, Chen H, Blumenfeld H. Neuroimage. 2021 May 15; 2021 Feb 27. PMID: 33647499.
Absence seizures and their relationship to depression and anxiety: Evidence for bidirectionality.Gruenbaum BF, Sandhu MRS, Bertasi RAO, Bertasi TGO, Schonwald A, Kurup A, Gruenbaum SE, Freedman IG, Funaro MC, Blumenfeld H, Sanacora G. Epilepsia. 2021 May; 2021 Mar 10. PMID: 33751566.
Parallel pathways to decreased subcortical arousal in focal limbic seizures.Zhao CW, Feng L, Sieu LA, Pok B, Gummadavelli A, Blumenfeld H. Epilepsia. 2020 Dec; 2020 Nov 9. PMID: 33165921.
ILAE Neuroimaging Task Force highlight: Review MRI scans with semiology in mind.Federico P, Ng DW, Bernasconi A, Bernhardt B, Blumenfeld H, Cendes F, Chinvarun Y, Jackson GD, Morgan V, Rampp S, Vaudano AE, Wang I. Epileptic Disord. 2020 Oct 1. PMID: 33063671.
The connectivity index: an effective metric for grading epileptogenicity.Yan Q, Gaspard N, Zaveri HP, Blumenfeld H, Hirsch LJ, Spencer DD, Alkawadri R. J Neurosurg. 2020 Oct 1; 2019 Sep 27. PMID: 31561212.
Thalamic Stimulation Improves Postictal Cortical Arousal and Behavior.Xu J, Galardi MM, Pok B, Patel KK, Zhao CW, Andrews JP, Singla S, McCafferty CP, Feng L, Musonza ET, Kundishora AJ, Gummadavelli A, Gerrard JL, Laubach M, Schiff ND, Blumenfeld H. J Neurosci. 2020 Sep 16; 2020 Aug 21. PMID: 32826310.
MRI essentials in epileptology: a review from the ILAE Imaging Taskforce.Wang I, Bernasconi A, Bernhardt B, Blumenfeld H, Cendes F, Chinvarun Y, Jackson G, Morgan V, Rampp S, Vaudano AE, Federico P. Epileptic Disord. 2020 Aug 1. PMID: 32763869.
Detecting Seizures and Epileptiform Abnormalities in Acute Brain Injury.Singla S, Garcia GE, Rovenolt GE, Soto AL, Gilmore EJ, Hirsch LJ, Blumenfeld H, Sheth KN, Omay SB, Struck AF, Westover MB, Kim JA. Curr Neurol Neurosci Rep. 2020 Jul 27; 2020 Jul 27. PMID: 32715371.
Up and Down States of Cortical Neurons in Focal Limbic Seizures.Yue Z, Freedman IG, Vincent P, Andrews JP, Micek C, Aksen M, Martin R, Zuckerman D, Perrenoud Q, Neske GT, Sieu LA, Bo X, Cardin JA, Blumenfeld H. Cereb Cortex. 2020 May 14. PMID: 31800015.
Motivational Interviewing Techniques to Improve Psychotherapy Adherence and Outcomes for Patients With Psychogenic Nonepileptic Seizures.Tolchin B, Baslet G, Martino S, Suzuki J, Blumenfeld H, Hirsch LJ, Altalib H, Dworetzky BA. J Neuropsychiatry Clin Neurosci. 2020 Spring; 2019 Aug 30. PMID: 31466516.
Realistic driving simulation during generalized epileptiform discharges to identify electroencephalographic features related to motor vehicle safety: Feasibility and pilot study.Cohen E, Antwi P, Banz BC, Vincent P, Saha R, Arencibia CA, Ryu JH, Atac E, Saleem N, Tomatsu S, Swift K, Hu C, Krestel H, Farooque P, Levy S, Wu J, Crowley M, Vaca FE, Blumenfeld H. Epilepsia. 2020 Jan; 2019 Oct 24. PMID: 31646628.
Contralateral ictal ptosis: Is it a reliable lateralizing sign in epilepsy?Sheikh Z, Blumenfeld H, Hirsch LJ. Neurol Clin Pract. 2019 Dec. PMID: 32042495.
Investigation of patient and observer agreement on description of seizures at initial clinical visit.Saleem MN, Arencibia CA, McKenna K, Cristofaro S, Detyniecki K, Friedman D, French J, Blumenfeld H. Ann Clin Transl Neurol. 2019 Dec; 2019 Dec 5. PMID: 31808615.
Author response: Adherence with psychotherapy and treatment outcomes for psychogenic nonepileptic seizures.Tolchin B, Dworetzky BA, Martino S, Blumenfeld H, Hirsch LJ, Baslet G. Neurology. 2019 Nov 26. PMID: 31767663.
Default mode and visual network activity in an attention task: Direct measurement with intracranial EEG.Li J, Kronemer SI, Herman WX, Kwon H, Ryu JH, Micek C, Wu Y, Gerrard J, Spencer DD, Blumenfeld H. Neuroimage. 2019 Nov 1; 2019 Jul 8. PMID: 31295566.
WONOEP appraisal: Network concept from an imaging perspective.Wykes RC, Khoo HM, Caciagli L, Blumenfeld H, Golshani P, Kapur J, Stern JM, Bernasconi A, Dedeurwaerdere S, Bernasconi N. Epilepsia. 2019 Jul; 2019 Jun 9. PMID: 31179547.
Randomized controlled trial of motivational interviewing for psychogenic nonepileptic seizures.Tolchin B, Baslet G, Suzuki J, Martino S, Blumenfeld H, Hirsch LJ, Altalib H, Dworetzky BA. Epilepsia. 2019 May; 2019 Apr 13. PMID: 30980679.
Historical trend toward improved long-term outcome in childhood absence epilepsy.Morse E, Giblin K, Chung MH, Dohle C, Berg AT, Blumenfeld H. Epilepsy Res. 2019 May; 2019 Feb 25. PMID: 30856420.
Slowing less than 1 Hz is decreased near the seizure onset zone.Lundstrom BN, Boly M, Duckrow R, Zaveri HP, Blumenfeld H. Sci Rep. 2019 Apr 17; 2019 Apr 17. PMID: 30996228.
Mechanisms of decreased cholinergic arousal in focal seizures: In vivo whole-cell recordings from the pedunculopontine tegmental nucleus.Andrews JP, Yue Z, Ryu JH, Neske G, McCormick DA, Blumenfeld H. Exp Neurol. 2019 Apr; 2018 Dec 10. PMID: 30543800.
Association of Seizure Spread With Surgical Failure in Epilepsy.Andrews JP, Gummadavelli A, Farooque P, Bonito J, Arencibia C, Blumenfeld H, Spencer DD. JAMA Neurol. 2019 Apr 1. PMID: 30508033.
Driving status of patients with generalized spike-wave on EEG but no clinical seizures.Antwi P, Atac E, Ryu JH, Arencibia CA, Tomatsu S, Saleem N, Wu J, Crowley MJ, Banz B, Vaca FE, Krestel H, Blumenfeld H. Epilepsy Behav. 2019 Mar; 2018 Dec 21. PMID: 30580109.
Optimization of Parameters for Quantitative Analysis of (123)I-Ioflupane SPECT Images for Monitoring Progression of Parkinson Disease.Kuo PH, Eshghi N, Tinaz S, Blumenfeld H, Louis ED, Zubal G. J Nucl Med Technol. 2019 Mar; 2018 Aug 23. PMID: 30139881.
Adherence with psychotherapy and treatment outcomes for psychogenic nonepileptic seizures.Tolchin B, Dworetzky BA, Martino S, Blumenfeld H, Hirsch LJ, Baslet G. Neurology. 2019 Feb 12; 2019 Jan 4. PMID: 30610097.
Opportunities and challenges for a maturing science of consciousness.Michel M, Beck D, Block N, Blumenfeld H, Brown R, Carmel D, Carrasco M, Chirimuuta M, Chun M, Cleeremans A, Dehaene S, Fleming SM, Frith C, Haggard P, He BJ, Heyes C, Goodale MA, Irvine L, Kawato M, Kentridge R, King JR, Knight RT, Kouider S, Lamme V, Lamy D, Lau H, Laureys S, LeDoux J, Lin YT, Liu K, Macknik SL, Martinez-Conde S, Mashour GA, Melloni L, Miracchi L, Mylopoulos M, Naccache L, Owen AM, Passingham RE, Pessoa L, Peters MAK, Rahnev D, Ro T, Rosenthal D, Sasaki Y, Sergent C, Solovey G, Schiff ND, Seth A, Tallon-Baudry C, Tamietto M, Tong F, van Gaal S, Vlassova A, Watanabe T, Weisberg J, Yan K, Yoshida M. Nat Hum Behav. 2019 Feb. PMID: 30944453.
A Switch and Wave of Neuronal Activity in the Cerebral Cortex During the First Second of Conscious Perception.Herman WX, Smith RE, Kronemer SI, Watsky RE, Chen WC, Gober LM, Touloumes GJ, Khosla M, Raja A, Horien CL, Morse EC, Botta KL, Hirsch LJ, Alkawadri R, Gerrard JL, Spencer DD, Blumenfeld H. Cereb Cortex. 2019 Feb 1. PMID: 29194517.
Presurgical language fMRI: Technical practices in epilepsy surgical planning.Benjamin CFA, Dhingra I, Li AX, Blumenfeld H, Alkawadri R, Bickel S, Helmstaedter C, Meletti S, Bronen RA, Warfield SK, Peters JM, Reutens D, Połczyńska MM, Hirsch LJ, Spencer DD. Hum Brain Mapp. 2018 Oct; 2018 Jul 1. PMID: 29962111.
Presurgical language fMRI: Clinical practices and patient outcomes in epilepsy surgical planning.Benjamin CFA, Li AX, Blumenfeld H, Constable RT, Alkawadri R, Bickel S, Helmstaedter C, Meletti S, Bronen R, Warfield SK, Peters JM, Reutens D, Połczyńska M, Spencer DD, Hirsch LJ. Hum Brain Mapp. 2018 Jul; 2018 Mar 12. PMID: 29528160.
Semiquantitative Analysis of Dopamine Transporter Scans in Patients With Parkinson Disease.Tinaz S, Chow C, Kuo PH, Krupinski EA, Blumenfeld H, Louis ED, Zubal G. Clin Nucl Med. 2018 Jan. PMID: 29112012.
Seizures and Sleep in the Thalamus: Focal Limbic Seizures Show Divergent Activity Patterns in Different Thalamic Nuclei.Feng L, Motelow JE, Ma C, Biche W, McCafferty C, Smith N, Liu M, Zhan Q, Jia R, Xiao B, Duque A, Blumenfeld H. J Neurosci. 2017 Nov 22; 2017 Oct 24. PMID: 29066556.
Impairment of consciousness induced by bilateral electrical stimulation of the frontal convexity.Quraishi IH, Benjamin CF, Spencer DD, Blumenfeld H, Alkawadri R. Epilepsy Behav Case Rep. 2017; 2017 Sep 29. PMID: 29204347.
Restoring Conscious Arousal During Focal Limbic Seizures with Deep Brain Stimulation.Kundishora AJ, Gummadavelli A, Ma C, Liu M, McCafferty C, Schiff ND, Willie JT, Gross RE, Gerrard J, Blumenfeld H. Cereb Cortex. 2017 Mar 1. PMID: 26941379.
Impaired consciousness in patients with absence seizures investigated by functional MRI, EEG, and behavioural measures: a cross-sectional study.Guo JN, Kim R, Chen Y, Negishi M, Jhun S, Weiss S, Ryu JH, Bai X, Xiao W, Feeney E, Rodriguez-Fernandez J, Mistry H, Crunelli V, Crowley MJ, Mayes LC, Constable RT, Blumenfeld H. Lancet Neurol. 2016 Dec. PMID: 27839650.
Metabolic demands of neural-hemodynamic associated and disassociated areas in brain.Sanganahalli BG, Herman P, Rothman DL, Blumenfeld H, Hyder F. J Cereb Blood Flow Metab. 2016 Oct; 2016 Aug 25. PMID: 27562867.
Impaired Serotonergic Brainstem Function during and after Seizures.Zhan Q, Buchanan GF, Motelow JE, Andrews J, Vitkovskiy P, Chen WC, Serout F, Gummadavelli A, Kundishora A, Furman M, Li W, Bo X, Richerson GB, Blumenfeld H. J Neurosci. 2016 Mar 2. PMID: 26937010.
Human bedside evaluation versus automatic responsiveness testing in epilepsy (ARTiE).Touloumes G, Morse E, Chen WC, Gober L, Dente J, Lilenbaum R, Katzenstein E, Pacelli A, Johnson E, Si Y, Sivaraju A, Grover E, Khozein R, Cunningham C, Hirsch LJ, Blumenfeld H. Epilepsia. 2016 Jan; 2015 Dec 10. PMID: 26663137.
Optogenetic stimulation of cholinergic brainstem neurons during focal limbic seizures: Effects on cortical physiology.Furman M, Zhan Q, McCafferty C, Lerner BA, Motelow JE, Meng J, Ma C, Buchanan GF, Witten IB, Deisseroth K, Cardin JA, Blumenfeld H. Epilepsia. 2015 Dec; 2015 Nov 4. PMID: 26530287.
Epileptic auras and their role in driving safety in people with epilepsy.Punia V, Farooque P, Chen W, Hirsch LJ, Berg AT, Blumenfeld H. Epilepsia. 2015 Nov; 2015 Sep 22. PMID: 26391317.
Targeting Neuronal Networks with Combined Drug and Stimulation Paradigms Guided by Neuroimaging to Treat Brain Disorders.Faingold CL, Blumenfeld H. Neuroscientist. 2015 Oct; 2015 Jul 6. PMID: 26150315.
Neurostimulation to improve level of consciousness in patients with epilepsy.Gummadavelli A, Kundishora AJ, Willie JT, Andrews JP, Gerrard JL, Spencer DD, Blumenfeld H. Neurosurg Focus. 2015 Jun. PMID: 26030698.
Seizures and brain regulatory systems: consciousness, sleep, and autonomic systems.Sedigh-Sarvestani M, Blumenfeld H, Loddenkemper T, Bateman LM. J Clin Neurophysiol. 2015 Jun. PMID: 25233249.
Rhythmic 3-4Hz discharge is insufficient to produce cortical BOLD fMRI decreases in generalized seizures.Youngblood MW, Chen WC, Mishra AM, Enamandram S, Sanganahalli BG, Motelow JE, Bai HX, Frohlich F, Gribizis A, Lighten A, Hyder F, Blumenfeld H. Neuroimage. 2015 Apr 1; 2015 Jan 3. PMID: 25562830.
Commentary: The return of consciousness to epilepsy seizure classification.Blumenfeld H, Meador K, Jackson GD. Epilepsia. 2015 Mar; 2015 Mar 5. PMID: 25740196.
Decreased subcortical cholinergic arousal in focal seizures.Motelow JE, Li W, Zhan Q, Mishra AM, Sachdev RN, Liu G, Gummadavelli A, Zayyad Z, Lee HS, Chu V, Andrews JP, Englot DJ, Herman P, Sanganahalli BG, Hyder F, Blumenfeld H. Neuron. 2015 Feb 4. PMID: 25654258.
Thalamic stimulation to improve level of consciousness after seizures: evaluation of electrophysiology and behavior.Gummadavelli A, Motelow JE, Smith N, Zhan Q, Schiff ND, Blumenfeld H. Epilepsia. 2015 Jan; 2014 Dec 2. PMID: 25442843.
Cortical network switching: possible role of the lateral septum and cholinergic arousal.Li W, Motelow JE, Zhan Q, Hu YC, Kim R, Chen WC, Blumenfeld H. Brain Stimul. 2015 Jan-Feb; 2014 Sep 16. PMID: 25440289.
Altered functional connectivity in seizure onset zones revealed by fMRI intrinsic connectivity.Lee HW, Arora J, Papademetris X, Tokoglu F, Negishi M, Scheinost D, Farooque P, Blumenfeld H, Spencer DD, Constable RT. Neurology. 2014 Dec 9; 2014 Nov 12. PMID: 25391304.
The spatial and signal characteristics of physiologic high frequency oscillations.Alkawadri R, Gaspard N, Goncharova II, Spencer DD, Gerrard JL, Zaveri H, Duckrow RB, Blumenfeld H, Hirsch LJ. Epilepsia. 2014 Dec; 2014 Dec 3. PMID: 25470216.
A master switch for consciousness?Blumenfeld H. Epilepsy Behav. 2014 Aug; 2014 Aug 2. PMID: 25090656.
Consciousness as a useful concept in epilepsy classification.Blumenfeld H, Meador KJ. Epilepsia. 2014 Aug; 2014 Jun 30. PMID: 24981294.
Impaired consciousness in partial seizures is bimodally distributed.Cunningham C, Chen WC, Shorten A, McClurkin M, Choezom T, Schmidt CP, Chu V, Bozik A, Best C, Chapman M, Furman M, Detyniecki K, Giacino JT, Blumenfeld H. Neurology. 2014 May 13; 2014 Apr 11. PMID: 24727311.
Decreased resting functional connectivity after traumatic brain injury in the rat.Mishra AM, Bai X, Sanganahalli BG, Waxman SG, Shatillo O, Grohn O, Hyder F, Pitkänen A, Blumenfeld H. PLoS One. 2014; 2014 Apr 18. PMID: 24748279.
Long-term seizure remission in childhood absence epilepsy: might initial treatment matter?Berg AT, Levy SR, Testa FM, Blumenfeld H. Epilepsia. 2014 Apr; 2014 Feb 11. PMID: 24512528.
Ictal spread of medial temporal lobe seizures with and without secondary generalization: an intracranial electroencephalography analysis.Yoo JY, Farooque P, Chen WC, Youngblood MW, Zaveri HP, Gerrard JL, Spencer DD, Hirsch LJ, Blumenfeld H. Epilepsia. 2014 Feb; 2014 Jan 13. PMID: 24417694.
What is a seizure network? Long-range network consequences of focal seizures.Blumenfeld H. Adv Exp Med Biol. 2014. PMID: 25012367.
Epilepsy and driving: potential impact of transient impaired consciousness.Chen WC, Chen EY, Gebre RZ, Johnson MR, Li N, Vitkovskiy P, Blumenfeld H. Epilepsy Behav. 2014 Jan. PMID: 24436967.
Consciousness of seizures and consciousness during seizures: are they related?Detyniecki K, Blumenfeld H. Epilepsy Behav. 2014 Jan; 2013 Oct 12. PMID: 24126026.
Anti-epileptogenesis: Electrophysiology, diffusion tensor imaging and behavior in a genetic absence model.van Luijtelaar G, Mishra AM, Edelbroek P, Coman D, Frankenmolen N, Schaapsmeerders P, Covolato G, Danielson N, Niermann H, Janeczko K, Kiemeneij A, Burinov J, Bashyal C, Coquillette M, Lüttjohann A, Hyder F, Blumenfeld H, van Rijn CM. Neurobiol Dis. 2013 Dec; 2013 Aug 23. PMID: 23978468.
Seizure localization using three-dimensional surface projections of intracranial EEG power.Lee HW, Youngblood MW, Farooque P, Han X, Jhun S, Chen WC, Goncharova I, Vives K, Spencer DD, Zaveri H, Hirsch LJ, Blumenfeld H. Neuroimage. 2013 Dec; 2013 Jul 11. PMID: 23850575.
Functional MRI and neural responses in a rat model of Alzheimer's disease.Sanganahalli BG, Herman P, Behar KL, Blumenfeld H, Rothman DL, Hyder F. Neuroimage. 2013 Oct 1; 2013 May 3. PMID: 23648961.
Quantitative basis for neuroimaging of cortical laminae with calibrated functional MRI.Herman P, Sanganahalli BG, Blumenfeld H, Rothman DL, Hyder F. Proc Natl Acad Sci U S A. 2013 Sep 10; 2013 Aug 26. PMID: 23980158.
Increased resting functional connectivity in spike-wave epilepsy in WAG/Rij rats.Mishra AM, Bai X, Motelow JE, Desalvo MN, Danielson N, Sanganahalli BG, Hyder F, Blumenfeld H. Epilepsia. 2013 Jul. PMID: 23815571.
Should consciousness be included in the classification of focal (partial) seizures?Blumenfeld H, Jackson GD. Epilepsia. 2013 Jun. PMID: 23731397.
Intracranial EEG surface renderings: new insights into normal and abnormal brain function.Youngblood MW, Han X, Farooque P, Jhun S, Bai X, Yoo JY, Lee HW, Blumenfeld H. Neuroscientist. 2013 Jun; 2012 May 31. PMID: 22653695.
Ethosuximide reduces epileptogenesis and behavioral comorbidity in the GAERS model of genetic generalized epilepsy.Dezsi G, Ozturk E, Stanic D, Powell KL, Blumenfeld H, O'Brien TJ, Jones NC. Epilepsia. 2013 Apr; 2013 Mar 6. PMID: 23464801.
Prospective assessment of ictal behavior using the revised Responsiveness in Epilepsy Scale (RES-II).Bauerschmidt A, Koshkelashvili N, Ezeani CC, Yoo JY, Zhang Y, Manganas LN, Kapadia K, Palenzuela D, Schmidt CC, Lief R, Kiely BT, Choezom T, McClurkin M, Shorten A, Detyniecki K, Hirsch LJ, Giacino JT, Blumenfeld H. Epilepsy Behav. 2013 Jan; 2012 Nov 30. PMID: 23201609.
Analysis of time and space invariance of BOLD responses in the rat visual system.Bailey CJ, Sanganahalli BG, Herman P, Blumenfeld H, Gjedde A, Hyder F. Cereb Cortex. 2013 Jan; 2012 Jan 31. PMID: 22298731.