2017
Unravelling the relationship between the tsetse fly and its obligate symbiont Wigglesworthia: transcriptomic and metabolomic landscapes reveal highly integrated physiological networks
Bing X, Attardo GM, Vigneron A, Aksoy E, Scolari F, Malacrida A, Weiss BL, Aksoy S. Unravelling the relationship between the tsetse fly and its obligate symbiont Wigglesworthia: transcriptomic and metabolomic landscapes reveal highly integrated physiological networks. Proceedings Of The Royal Society B 2017, 284: 20170360. PMID: 28659447, PMCID: PMC5489720, DOI: 10.1098/rspb.2017.0360.Peer-Reviewed Original ResearchConceptsPeptidoglycan recognition proteinsAfrican trypanosome parasitesTsetse fliesAmino acid metabolismWigglesworthia glossinidiaMultiple metabolic pathwaysObligate endosymbiontsMolecular chaperonesTransport machineryVertebrate bloodMetabolomic landscapeRecognition proteinsSeq analysisSymbiotic dialogueNucleotide biosynthesisAdenosyl methionineBiological functionsSpecialized cellsTsetse survivalTrypanosome parasitesEssential cofactorMetabolic pathwaysNew biological targetsAcid metabolismPhysiological networks
2001
A novel application of gene arrays: Escherichia coli array provides insight into the biology of the obligate endosymbiont of tsetse flies
Akman L, Aksoy S. A novel application of gene arrays: Escherichia coli array provides insight into the biology of the obligate endosymbiont of tsetse flies. Proceedings Of The National Academy Of Sciences Of The United States Of America 2001, 98: 7546-7551. PMID: 11404467, PMCID: PMC34705, DOI: 10.1073/pnas.131057498.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBacterial ProteinsDNA MethylationDNA ReplicationDNA, BacterialDNA, ComplementaryEnterobacteriaceaeEscherichia coliGenome, BacterialMolecular Sequence DataNucleic Acid HybridizationOligonucleotide Array Sequence AnalysisProtein BiosynthesisSymbiosisTranscription, GeneticTsetse FliesConceptsObligate endosymbiontsComplete genome sequence dataGene arrayBiosynthesis of cofactorsE. coli genesGenome sequence dataTsetse fliesFacultative anaerobic organismsObligate symbiontsOrthologous genesWigglesworthia glossinidiaSmall genomesGenome sizeSymbiotic associationGenome informationDNA replicationRelated organismsColi geneSymbiotic lifeSequence dataWigglesworthiaGene productsExpression analysisTransport proteinsExpression profiles