Publications

2025

Treatment of Extraosseous Giant Cell Tumor of Bone and Calcitriol-Mediated Hypercalcemia With Denosumab in Paget Disease.Magvanjav O, Bergwitz C. Treatment of Extraosseous Giant Cell Tumor of Bone and Calcitriol-Mediated Hypercalcemia With Denosumab in Paget Disease. JCEM Case Rep 2025, 3: luaf031. PMID: 40110572, DOI: 10.1210/jcemcr/luaf031.
The effect of altered sleep timing on glycaemic outcomes: Systematic review of human intervention studies.Slebe R, Splinter JJ, Schoonmade LJ, Blondin DP, Campbell DJT, Carpentier AC, Després JP, Hoeks J, Kalsbeek A, Raina P, Schrauwen P, Serlie MJ, Stenvers DJ, Yi CX, de Mutsert R, Beulens JWJ, Rutters F. The effect of altered sleep timing on glycaemic outcomes: Systematic review of human intervention studies. Diabetes Obes Metab 2025, 27: 1172-1183. PMID: 39605179, DOI: 10.1111/dom.16104.
A case of undifferentiated shock found to be due to voriconazole-related primary adrenal insufficiencyKaleena Zhang and Bergwitz C A case of undifferentiated shock found to be due to voriconazole-related primary adrenal insufficiency Ann Int Med: Clinical Cases, 2025, 24-0180R1 (accepted manuscript)
International Consortium to Classify Ageing-related Pathologies (ICCARP) senescence definitions: achieving international consensusShort E, Huckstepp R, Alavian K, Amoaku W, Barber T, van Beek E, Benbow E, Bhandari S, Bloom P, Cota C, Chazot P, Christopher G, Demaria M, Erusalimsky J, Ferenbach D, Foster T, Gazzard G, Glassock R, Jamal N, Kalaria R, Kanamarlapudi V, Khan A, Krishna Y, Leeuwenburgh C, van der Linde I, Lorenzini A, Maier A, Medina R, Miotto C, Mukherjee A, Mukkanna K, Murray J, Nirenberg A, Palmer D, Pawelec G, Reddy V, Rosa A, Rule A, Shiels P, Sheridan C, Tree J, Tsimpida D, Venables Z, Wellington J, Calimport S, Bentley B. International Consortium to Classify Ageing-related Pathologies (ICCARP) senescence definitions: achieving international consensus. GeroScience 2025, 1-8. PMID: 39982667, DOI: 10.1007/s11357-025-01509-9.
[The treatment of intolerance for enteral nutrition of unknown origin with parenteral nutrition].Korzilius JW, Dijkstra G, Keszthelyi D, van den Heuvel TJ, Serlie MJ, Wanten GJA. [The treatment of intolerance for enteral nutrition of unknown origin with parenteral nutrition]. Ned Tijdschr Geneeskd 2025, 169 PMID: 39976485.
Short- and long-term glycemic effects of pasireotide in patients with acromegaly: a comprehensive case study with review of literatureTaki Y, Kono T, Matsuda T, Kozu R, Fujimoto M, Sakuma I, Hashimoto N, Horiguchi K, Higuchi Y, Tanaka T. Short- and long-term glycemic effects of pasireotide in patients with acromegaly: a comprehensive case study with review of literature. Endocrine Journal 2025, ej24-0548. PMID: 39842795, DOI: 10.1507/endocrj.ej24-0548.
Integrated Stepped Alcohol Treatment With Contingency Management for Unhealthy Alcohol Use Among People With HIV: A Randomized Controlled TrialEdelman E, Dziura J, Deng Y, DePhilippis D, Ferguson T, Brown S, Marconi V, Goetz M, Rodriguez-Barradas M, Simberkoff M, Molina P, Weintrob A, Maisto S, Paris M, Justice A, Bryant K, Fiellin D. Integrated Stepped Alcohol Treatment With Contingency Management for Unhealthy Alcohol Use Among People With HIV: A Randomized Controlled Trial. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2025, 98: 72-81. PMID: 39321757, DOI: 10.1097/qai.0000000000003534.

2024

SGLT2 inhibition alters substrate utilization and mitochondrial redox in healthy and failing rat heartsGoedeke L, Ma Y, Gaspar R, Nasiri A, Lee J, Zhang D, Galsgaard K, Hu X, Zhang J, Guerrera N, Li X, LaMoia T, Hubbard B, Haedersdal S, Wu X, Stack J, Dufour S, Butrico G, Kahn M, Perry R, Cline G, Young L, Shulman G. SGLT2 inhibition alters substrate utilization and mitochondrial redox in healthy and failing rat hearts. Journal Of Clinical Investigation 2024, 134: e176708. PMID: 39680452, PMCID: PMC11645152, DOI: 10.1172/jci176708.
Characteristics of autoantibody-positive individuals without high-risk HLA-DR4-DQ8 or HLA-DR3-DQ2 haplotypesRedondo M, Cuthbertson D, Steck A, Herold K, Oram R, Atkinson M, Brusko T, Parikh H, Krischer J, Onengut-Gumuscu S, Rich S, Sosenko J. Characteristics of autoantibody-positive individuals without high-risk HLA-DR4-DQ8 or HLA-DR3-DQ2 haplotypes. Diabetologia 2024, 1-14. PMID: 39670998, DOI: 10.1007/s00125-024-06338-7.
Reversing Diabetes With Your Own Cells: Closer to the DreamGenosar R, Coman M, Herold K. Reversing Diabetes With Your Own Cells: Closer to the Dream. The Journal Of Clinical Endocrinology & Metabolism 2024, dgae851. PMID: 39673177, DOI: 10.1210/clinem/dgae851.
Renal Angptl4 is a key fibrogenic molecule in progressive diabetic kidney diseaseSrivastava S, Zhou H, Shenoi R, Morris M, Lainez-Mas B, Goedeke L, Rajendran B, Setia O, Aryal B, Kanasaki K, Koya D, Inoki K, Dardik A, Bell T, Fernández-Hernando C, Shulman G, Goodwin J. Renal Angptl4 is a key fibrogenic molecule in progressive diabetic kidney disease. Science Advances 2024, 10: eadn6068. PMID: 39630889, PMCID: PMC11616692, DOI: 10.1126/sciadv.adn6068.
Eligibility for Anti-Obesity Medications through Medicare for Older Adults with Overweight or ObesityChetty A, Khunte M, Chen A, Jastreboff A, Krumholz H, Lu Y. Eligibility for Anti-Obesity Medications through Medicare for Older Adults with Overweight or Obesity. American Heart Journal 2024, 278: 8. DOI: 10.1016/j.ahj.2024.09.022.
Corrigendum to “PTH-dependent stabilization of RANKL mRNA is associated with increased phosphorylation of the KH-type splicing regulatory protein” [Molecul. Cellul. Endocrinol. 595 (2025) 112412]Yao G, Zhu M, Insogna K. Corrigendum to “PTH-dependent stabilization of RANKL mRNA is associated with increased phosphorylation of the KH-type splicing regulatory protein” [Molecul. Cellul. Endocrinol. 595 (2025) 112412]. Molecular And Cellular Endocrinology 2024, 112429. PMID: 39616004, DOI: 10.1016/j.mce.2024.112429.
UBXN9 governs GLUT4-mediated spatial confinement of RIG-I-like receptors and signalingHarrison A, Yang D, Cahoon J, Geng T, Cao Z, Karginov T, Hu Y, Li X, Chiari C, Qyang Y, Vella A, Fan Z, Vanaja S, Rathinam V, Witczak C, Bogan J, Wang P. UBXN9 governs GLUT4-mediated spatial confinement of RIG-I-like receptors and signaling. Nature Immunology 2024, 25: 2234-2246. PMID: 39567760, DOI: 10.1038/s41590-024-02004-7.
Trajectory of beta cell function and insulin clearance in stage 2 type 1 diabetes: natural history and response to teplizumabGalderisi A, Sims E, Evans-Molina C, Petrelli A, Cuthbertson D, Nathan B, Ismail H, Herold K, Moran A. Trajectory of beta cell function and insulin clearance in stage 2 type 1 diabetes: natural history and response to teplizumab. Diabetologia 2024, 1-16. PMID: 39560746, DOI: 10.1007/s00125-024-06323-0.
Metastasis of colon cancer requires Dickkopf-2 to generate cancer cells with Paneth cell properties.Shin J, Park J, Lim J, Jeong J, Dinesh R, Maher S, Kim J, Park S, Hong J, Wysolmerski J, Choi J, Bothwell A. Metastasis of colon cancer requires Dickkopf-2 to generate cancer cells with Paneth cell properties. ELife 2024, 13 PMID: 39535280, PMCID: PMC11560131, DOI: 10.7554/elife.97279.
Metastasis of colon cancer requires Dickkopf-2 to generate cancer cells with Paneth cell propertiesShin J, Park J, Lim J, Jeong J, Dinesh R, Maher S, Kim J, Park S, Hong J, Wysolmerski J, Choi J, Bothwell A. Metastasis of colon cancer requires Dickkopf-2 to generate cancer cells with Paneth cell properties. ELife 2024, 13 DOI: 10.7554/elife.97279.3.
Tirzepatide for Obesity Treatment and Diabetes PreventionJastreboff A, le Roux C, Stefanski A, Aronne L, Halpern B, Wharton S, Wilding J, Perreault L, Zhang S, Battula R, Bunck M, Ahmad N, Jouravskaya I. Tirzepatide for Obesity Treatment and Diabetes Prevention. New England Journal Of Medicine 2024 PMID: 39536238, DOI: 10.1056/nejmoa2410819.
Abstract 4140057: Defining Severe Heart Failure across the Ejection Fraction Spectrum in DAPA-HF and DELIVERInciardi R, Lu H, Claggett B, Desai A, Jhund P, Lam C, Kosiborod M, Inzucchi S, Martinez F, De Boer R, Hernandez A, Shah S, Kober L, Ponikowski P, Sabatine M, Petersson M, Langkilde A, McMurray J, Vaduganathan M, Solomon S. Abstract 4140057: Defining Severe Heart Failure across the Ejection Fraction Spectrum in DAPA-HF and DELIVER. Circulation 2024, 150: a4140057-a4140057. DOI: 10.1161/circ.150.suppl_1.4140057.
PTH-dependent stabilization of RANKL mRNA is associated with increased phosphorylation of the KH-type splicing regulatory proteinYao G, Zhu M, Insogna K. PTH-dependent stabilization of RANKL mRNA is associated with increased phosphorylation of the KH-type splicing regulatory protein. Molecular And Cellular Endocrinology 2024, 595: 112412. PMID: 39536935, DOI: 10.1016/j.mce.2024.112412.
Efficacy and Safety of Apixaban for Pediatric Patients Requiring Anticoagulation for Treatment of Venous ThromboembolismDriscoll J, O'Brien S, Newburger J, Mitchell L, Holzhauer S, Ahuja S, Rubio A, Gaitonde P, Robertson A, Polinsky M, Masiukiewicz U, Brandao L. Efficacy and Safety of Apixaban for Pediatric Patients Requiring Anticoagulation for Treatment of Venous Thromboembolism. Blood 2024, 144: 295-295. DOI: 10.1182/blood-2024-198612.
Cost-Related Prescription Drug Rationing by Adults With ObesityChen A, Borden C, Canavan M, Ross J, Oladele C, Lipska K. Cost-Related Prescription Drug Rationing by Adults With Obesity. JAMA Network Open 2024, 7: e2433000. PMID: 39499520, PMCID: PMC11539006, DOI: 10.1001/jamanetworkopen.2024.33000.
Survodutide for treatment of obesity: rationale and design of two randomized phase 3 clinical trials (SYNCHRONIZE™‐1 and ‐2)Wharton S, le Roux C, Kosiborod M, Platz E, Brueckmann M, Jastreboff A, Hussain S, Pedersen S, Borowska L, Unseld A, Kloer I, Kaplan L, committees and investigators T. Survodutide for treatment of obesity: rationale and design of two randomized phase 3 clinical trials (SYNCHRONIZE™‐1 and ‐2). Obesity 2024, 33: 67-77. PMID: 39495965, PMCID: PMC11664303, DOI: 10.1002/oby.24184.
Molecular Profiling of Mouse Models of Loss or Gain of Function of the KCNT1 (Slack) Potassium Channel and Antisense Oligonucleotide TreatmentSun F, Wang H, Wu J, Quraishi I, Zhang Y, Pedram M, Gao B, Jonas E, Nguyen V, Wu S, Mabrouk O, Jafar-nejad P, Kaczmarek L. Molecular Profiling of Mouse Models of Loss or Gain of Function of the KCNT1 (Slack) Potassium Channel and Antisense Oligonucleotide Treatment. Biomolecules 2024, 14: 1397. PMID: 39595574, PMCID: PMC11591899, DOI: 10.3390/biom14111397.
Screening, brief intervention, and referral to treatment for pain management for veterans separating from military service: study protocol of a hybrid type 2 study testing implementation facilitation versus training-as-usualSellinger J, Rosen M, Lazar C, Gilstad-Hayden K, Dziura J, Li F, Mattocks K, Weede A, Sullivan-Tibbs M, Rose L, Vassallo G, Manhapra A, Turner A, Vogt D, Woodward E, Hartmann C, Haskell S, Mohammad A, Martino S. Screening, brief intervention, and referral to treatment for pain management for veterans separating from military service: study protocol of a hybrid type 2 study testing implementation facilitation versus training-as-usual. Pain Medicine 2024, 25: s99-s106. PMID: 39514877, DOI: 10.1093/pm/pnae062.
Adapting to change: experiences and recommendations from the Pain Management Collaboratory on modifying statistical analysis plansYu Q, George S, Kyriakides T, Rhon D, Morasco B, Dziura J, Fritz J, Geda M, Peduzzi P, Long C. Adapting to change: experiences and recommendations from the Pain Management Collaboratory on modifying statistical analysis plans. Pain Medicine 2024, 25: s49-s53. PMID: 39514871, PMCID: PMC11548855, DOI: 10.1093/pm/pnae073.
Utility of the PICOTS framework to assess clinical trial disruptions: monitoring the impact of COVID-19 in the Pain Management CollaboratoryPeduzzi P, Brandt C, Dearth C, Dziura J, Farrokhi S, George S, Kyriakides T, Long C, Mascha E, Patterson C, Rhon D, Kerns R. Utility of the PICOTS framework to assess clinical trial disruptions: monitoring the impact of COVID-19 in the Pain Management Collaboratory. Pain Medicine 2024, 25: s34-s40. PMID: 39514876, PMCID: PMC11548861, DOI: 10.1093/pm/pnae078.
Recommendations for monitoring adherence and fidelity in pragmatic trials based on experience in the Pain Management CollaboratoryDziura J, Gilstad-Hayden K, Coffman C, Long C, Yu Q, Buta E, Coggeshall S, Geda M, Peduzzi P, Kyriakides T. Recommendations for monitoring adherence and fidelity in pragmatic trials based on experience in the Pain Management Collaboratory. Pain Medicine 2024, 25: s41-s48. PMID: 39514878, PMCID: PMC11548857, DOI: 10.1093/pm/pnae080.
Eligibility for Anti-Obesity Medications Among Medicare Beneficiaries with Overweight or ObesityChetty A, Khunte M, Chen A, Jastreboff A, Krumholz H, Lu Y. Eligibility for Anti-Obesity Medications Among Medicare Beneficiaries with Overweight or Obesity. Journal Of General Internal Medicine 2024, 1-3. PMID: 39477867, DOI: 10.1007/s11606-024-09178-8.
Comparative analysis of aldosterone and renin assays for primary aldosteronism screeningTaki Y, Kono T, Teruyama K, Ichijo T, Sakuma I, Nagano H, Miyagawa H, Kono S, Fujimoto M, Hashimoto N, Yokoyama M, Kawakami E, Miki T, Tanaka T. Comparative analysis of aldosterone and renin assays for primary aldosteronism screening. Scientific Reports 2024, 14: 26040. PMID: 39472614, PMCID: PMC11522277, DOI: 10.1038/s41598-024-75645-1.
Effects of dapagliflozin in heart failure according to duration of type 2 diabetes: a patient-level meta-analysis of DAPA-HF and DELIVERButt J, De Boer R, Hernandez A, Inzucchi S, Kosiborod M, Koeber L, Lam C, Martinez F, Ponikowski P, Sabatine M, Shah S, Vaduganathan M, Jhund P, Solomon S, Mcmurray J. Effects of dapagliflozin in heart failure according to duration of type 2 diabetes: a patient-level meta-analysis of DAPA-HF and DELIVER. European Heart Journal 2024, 45: ehae666.1097. DOI: 10.1093/eurheartj/ehae666.1097.
Understanding the impact of night-to-night sleep variations on glucose regulation in healthy young adults: Insights from Ng et al. (2024)Ding Q, Wojeck B, Zinchuk A. Understanding the impact of night-to-night sleep variations on glucose regulation in healthy young adults: Insights from Ng et al. (2024). Sleep 2024, zsae253. PMID: 39460669, DOI: 10.1093/sleep/zsae253.
Risk of Infection in Older Adults With Type 2 Diabetes With Relaxed Glycemic Control.Lipska K, Gilliam L, Lee C, Liu J, Liu V, Moffet H, Parker M, Zapata H, Karter A. Risk of Infection in Older Adults With Type 2 Diabetes With Relaxed Glycemic Control. Diabetes Care 2024, 47: 2258-2265. PMID: 39436715, PMCID: PMC11655405, DOI: 10.2337/dc24-1612.
Chromogranin B Purification for Condensate Formation and Client Partitioning Assays In VitroParchure A, von Blume J. Chromogranin B Purification for Condensate Formation and Client Partitioning Assays In Vitro. Bio-protocol 2024, 14: e5095. PMID: 39512880, PMCID: PMC11540053, DOI: 10.21769/bioprotoc.5095.
Sustained caloric restriction potentiates insulin action by activating prostacyclin synthaseMerali C, Quinn C, Huffman K, Pieper C, Bogan J, Barrero C, Merali S. Sustained caloric restriction potentiates insulin action by activating prostacyclin synthase. Obesity 2024, 32: 2286-2298. PMID: 39420421, DOI: 10.1002/oby.24150.
Machine Learning-Based Prediction of Death and Hospitalization in Patients With Implantable Cardioverter DefibrillatorsRosman L, Lampert R, Wang K, Gehi A, Dziura J, Salmoirago-Blotcher E, Brandt C, Sears S, Burg M. Machine Learning-Based Prediction of Death and Hospitalization in Patients With Implantable Cardioverter Defibrillators. Journal Of The American College Of Cardiology 2024 PMID: 39570241, DOI: 10.1016/j.jacc.2024.09.006.
High-fat-diet-induced hepatic insulin resistance per se attenuates murine de novo lipogenesisGoedeke L, Strober J, Suh R, Paolella L, Li X, Rogers J, Petersen M, Nasiri A, Casals G, Kahn M, Cline G, Samuel V, Shulman G, Vatner D. High-fat-diet-induced hepatic insulin resistance per se attenuates murine de novo lipogenesis. IScience 2024, 27: 111175. PMID: 39524330, PMCID: PMC11550620, DOI: 10.1016/j.isci.2024.111175.
7418 Xanthoma Disseminatum - A Rare cause of Diabetes InsipidusBalasubramanian P, Cohen J, Corbin Z, Panse G, Inzucchi S. 7418 Xanthoma Disseminatum - A Rare cause of Diabetes Insipidus. Journal Of The Endocrine Society 2024, 8: bvae163.1380. PMCID: PMC11454384, DOI: 10.1210/jendso/bvae163.1380.
12241 Association Between Brain Glucose And Circulating Glucagon Levels In Response To Acute HyperglycemiaMatson B, Gunawan F, Coppoli A, Jiang L, Rangel E, De Aguiar R, Rothman D, Mason G, Hwang J. 12241 Association Between Brain Glucose And Circulating Glucagon Levels In Response To Acute Hyperglycemia. Journal Of The Endocrine Society 2024, 8: bvae163.674. PMCID: PMC11454728, DOI: 10.1210/jendso/bvae163.674.
6645 Paraganglioma or Benign Ectopic Thyroid Tissue?Dower J, MacLeod R, Cardoso B, Matouk C, Mehra S, Riccio G, Williams L, Majumdar S. 6645 Paraganglioma or Benign Ectopic Thyroid Tissue? Journal Of The Endocrine Society 2024, 8: bvae163.2032. PMCID: PMC11454000, DOI: 10.1210/jendso/bvae163.2032.
7045 A Rare Case of Lyme-Associated Thyroiditis in an Otherwise Healthy PatientWindham M, Majumdar S. 7045 A Rare Case of Lyme-Associated Thyroiditis in an Otherwise Healthy Patient. Journal Of The Endocrine Society 2024, 8: bvae163.1865. PMCID: PMC11454719, DOI: 10.1210/jendso/bvae163.1865.
6421 Imaging Phenotype May Predict Genotype In Human Pheochromocytoma: Relationships Between Genetic Mutation Clusters, Metabolite Transporter Expression, And Radiotracer UptakeSakuma I, Fujimoto M, Vatner D, Yokote K, Tanaka T. 6421 Imaging Phenotype May Predict Genotype In Human Pheochromocytoma: Relationships Between Genetic Mutation Clusters, Metabolite Transporter Expression, And Radiotracer Uptake. Journal Of The Endocrine Society 2024, 8: bvae163.210. PMCID: PMC11455308, DOI: 10.1210/jendso/bvae163.210.
9365 Now You See Me: The Case Of The Ectopic ThyroidSuarez S, Majumdar S. 9365 Now You See Me: The Case Of The Ectopic Thyroid. Journal Of The Endocrine Society 2024, 8: bvae163.2018. PMCID: PMC11454156, DOI: 10.1210/jendso/bvae163.2018.
7029 Changes In Adrenal Gland Size Seen By Linear Assessment On Routine Abdominal CT During Critical IllnessVangipuram D, Bhagat N, Borkar R, Mazengia N, Williams S, Majumdar S. 7029 Changes In Adrenal Gland Size Seen By Linear Assessment On Routine Abdominal CT During Critical Illness. Journal Of The Endocrine Society 2024, 8: bvae163.133. PMCID: PMC11454092, DOI: 10.1210/jendso/bvae163.133.
9295 Characteristics Of Adults with Autosomal Dominant Hypocalcemia Type 1 (ADH1) Enrolled In The CLARIFY Disease Monitoring StudyIng S, Harmatz P, Mora S, Imel E, Tebben P, Warren M, Ma N, Khan A, Palermo A, Decallonne B, Lemoine S, Mantovani G, Linglart A, Wasserman H, Barbosa A, Cardot-Bauters C, Roberts M, Mathew A, Adler S, Zillikens M, Clifton-Bligh R, Rejnmark L. 9295 Characteristics Of Adults with Autosomal Dominant Hypocalcemia Type 1 (ADH1) Enrolled In The CLARIFY Disease Monitoring Study. Journal Of The Endocrine Society 2024, 8: bvae163.383. PMCID: PMC11454366, DOI: 10.1210/jendso/bvae163.383.
8669 Characteristics Of Adults with Autosomal Dominant Hypocalcemia Type 1 (ADH1) Enrolled In The CLARIFY Disease Monitoring StudyIng S, Harmatz P, Mora S, Imel E, Tebben P, Warren M, Ma N, Khan A, Palermo A, Decallonne B, Lemoine S, Mantovani G, Linglart A, Wasserman H, Barbosa A, Cardot-Bauters C, Roberts M, Mathew A, Adler S, Zillikens M, Clifton-Bligh R, Rejnmark L. 8669 Characteristics Of Adults with Autosomal Dominant Hypocalcemia Type 1 (ADH1) Enrolled In The CLARIFY Disease Monitoring Study. Journal Of The Endocrine Society 2024, 8: bvae163.384. PMCID: PMC11454712, DOI: 10.1210/jendso/bvae163.384.
7168 Papillary thyroid carcinoma co-existing with intrathyroidal metastasis from lung neuroendocrine tumorBalasubramanian P, Ladenheim A, Gilani S, Gibson C, Kunz P. 7168 Papillary thyroid carcinoma co-existing with intrathyroidal metastasis from lung neuroendocrine tumor. Journal Of The Endocrine Society 2024, 8: bvae163.2027. PMCID: PMC11453623, DOI: 10.1210/jendso/bvae163.2027.
Deciphering craniopharyngioma subtypes: Single-cell analysis of tumor microenvironment and immune networksMatsuda T, Kono T, Taki Y, Sakuma I, Fujimoto M, Hashimoto N, Kawakami E, Fukuhara N, Nishioka H, Inoshita N, Yamada S, Nakamura Y, Horiguchi K, Miki T, Higuchi Y, Tanaka T. Deciphering craniopharyngioma subtypes: Single-cell analysis of tumor microenvironment and immune networks. IScience 2024, 27: 111068. PMID: 39483146, PMCID: PMC11525618, DOI: 10.1016/j.isci.2024.111068.
GLP-1 programs the neurovascular landscapeChen B, Yu X, Horvath-Diano C, Ortuño M, Tschöp M, Jastreboff A, Schneeberger M. GLP-1 programs the neurovascular landscape. Cell Metabolism 2024, 36: 2173-2189. PMID: 39357509, DOI: 10.1016/j.cmet.2024.09.003.
Clinician-caregiver informant discrepancy is associated with sex, diagnosis age, and intervention use among autistic children.Azu M, Han G, Wolf J, Naples A, Chawarska K, Dawson G, Bernier R, Jeste S, Dziura J, Webb S, Sugar C, Shic F, McPartland J. Clinician-caregiver informant discrepancy is associated with sex, diagnosis age, and intervention use among autistic children. Autism 2024, 13623613241279999. PMID: 39344965, DOI: 10.1177/13623613241279999.
Small molecules targeting selective PCK1 and PGC-1α lysine acetylation cause anti-diabetic action through increased lactate oxidationMutlu B, Sharabi K, Sohn J, Yuan B, Latorre-Muro P, Qin X, Yook J, Lin H, Yu D, Camporez J, Kajimura S, Shulman G, Hui S, Kamenecka T, Griffin P, Puigserver P. Small molecules targeting selective PCK1 and PGC-1α lysine acetylation cause anti-diabetic action through increased lactate oxidation. Cell Chemical Biology 2024, 31: 1772-1786.e5. PMID: 39341205, PMCID: PMC11500315, DOI: 10.1016/j.chembiol.2024.09.001.
Ceramide synthesis inhibitors prevent lipid-induced insulin resistance through the DAG-PKCε-insulin receptorT1150 phosphorylation pathwayXu W, Zhang D, Ma Y, Gaspar R, Kahn M, Nasiri A, Murray S, Samuel V, Shulman G. Ceramide synthesis inhibitors prevent lipid-induced insulin resistance through the DAG-PKCε-insulin receptorT1150 phosphorylation pathway. Cell Reports 2024, 43: 114746. PMID: 39302831, DOI: 10.1016/j.celrep.2024.114746.
In‐hospital course of patients with heart failure with improved ejection fraction in the DELIVER trialPabon M, Vaduganathan M, Claggett B, Chatur S, Siqueira S, Marti‐Castellote P, de Boer R, Hernandez A, Inzucchi S, Kosiborod M, Lam C, Martinez F, Shah S, Desai A, Jhund P, McMurray J, Solomon S, Vardeny O. In‐hospital course of patients with heart failure with improved ejection fraction in the DELIVER trial. European Journal Of Heart Failure 2024 PMID: 39300780, DOI: 10.1002/ejhf.3410.
Considerations for the design and conduct of pediatric obesity pharmacotherapy clinical trials: Proceedings of expert roundtable meetingsKelly A, Bahlke M, Baker J, de Beaufort C, Belin R, Fonseca H, Hale P, Holm J, Hsia D, Jastreboff A, Juliusson P, Murphy M, Pak J, Paul E, Rudolph B, Srivastava G, Tornøe C, Weghuber D, Fox C. Considerations for the design and conduct of pediatric obesity pharmacotherapy clinical trials: Proceedings of expert roundtable meetings. Pediatric Obesity 2024, 19: e13161. PMID: 39289849, DOI: 10.1111/ijpo.13161.
Regulatory CD4+ T cells redirected against pathogenic CD8+ T cells protect NOD mice from development of autoimmune diabetesKakabadse D, Chen D, Fishman S, Weinstein-Marom H, Davies J, Wen L, Gross G, Wong F. Regulatory CD4+ T cells redirected against pathogenic CD8+ T cells protect NOD mice from development of autoimmune diabetes. Frontiers In Immunology 2024, 15: 1463971. PMID: 39351219, PMCID: PMC11439686, DOI: 10.3389/fimmu.2024.1463971.
Abstract PR-06: Dietary fats dictate pancreatic cancer fate via phospholipid saturationRuiz C, Ge X, McDonnell R, McQuaid D, Kaplan J, Li G, Rudolph M, Gorelick F, Wysolmerski J, Canals D, Haley J, Rodeheffer M, Muzumdar M. Abstract PR-06: Dietary fats dictate pancreatic cancer fate via phospholipid saturation. Cancer Research 2024, 84: pr-06-pr-06. DOI: 10.1158/1538-7445.pancreatic24-pr-06.
Abstract PR-05: Endocrine beta-cell stress promotes pancreatic ductal adenocarcinoma through endocrine-exocrine cell crosstalkGarcia C, Venkat A, McQuaid D, Agabiti S, Tong A, Cardone R, Kibbey R, Krishnaswamy S, Muzumdar M. Abstract PR-05: Endocrine beta-cell stress promotes pancreatic ductal adenocarcinoma through endocrine-exocrine cell crosstalk. Cancer Research 2024, 84: pr-05-pr-05. DOI: 10.1158/1538-7445.pancreatic24-pr-05.
Effect of Weight Loss on Skeletal Muscle Bioactive Lipids in People With Obesity and Type 2 Diabetes.Petersen M, Yoshino M, Smith G, Gaspar R, Kahn M, Samovski D, Shulman G, Klein S. Effect of Weight Loss on Skeletal Muscle Bioactive Lipids in People With Obesity and Type 2 Diabetes. Diabetes 2024, 73: 2055-2064. PMID: 39264820, PMCID: PMC11579410, DOI: 10.2337/db24-0083.
Dapagliflozin in Heart Failure, Type 2 Diabetes, and Neuropathy A Meta-Analysis of DAPA-HF and DELIVERButt J, Shen L, Inzucchi S, Docherty K, Jhund P, Martinez F, Sabatine M, Vaduganathan M, Solomon S, McMurray J, Committees and Investigators D. Dapagliflozin in Heart Failure, Type 2 Diabetes, and Neuropathy A Meta-Analysis of DAPA-HF and DELIVER. JACC Heart Failure 2024, 12: 1946-1948. PMID: 39269393, DOI: 10.1016/j.jchf.2024.07.017.
Spatiotemporal Eye Movement Dynamics Reveal Altered Face Prioritization in Early Visual Processing Among Autistic ChildrenGriffin J, Naples A, Bernier R, Chawarska K, Dawson G, Dziura J, Faja S, Jeste S, Kleinhans N, Sugar C, Webb S, Shic F, McPartland J, Trials A. Spatiotemporal Eye Movement Dynamics Reveal Altered Face Prioritization in Early Visual Processing Among Autistic Children. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2024 PMID: 39237004, DOI: 10.1016/j.bpsc.2024.08.017.
Abstract P137: Real-World Impact of Semaglutide on Cardiometabolic Risk Factors in Patients without Diabetes: A Multi-Center Analysis of Electronic Health RecordsKim C, Liu Y, Jastreboff A, Khera R, Krumholz H, Brush J, Lu Y. Abstract P137: Real-World Impact of Semaglutide on Cardiometabolic Risk Factors in Patients without Diabetes: A Multi-Center Analysis of Electronic Health Records. Hypertension 2024, 81: ap137-ap137. DOI: 10.1161/hyp.81.suppl_1.p137.
Mitochondrial ATP synthase as a novel therapeutic drug target in neurodegenerative and ischemic heart diseasesKumar A, da Fonseca Rezende e Mello J, Wu Y, Mezghani I, Smith E, Mnatsakanyan N. Mitochondrial ATP synthase as a novel therapeutic drug target in neurodegenerative and ischemic heart diseases. Biochimica Et Biophysica Acta (BBA) - Bioenergetics 2024, 1865: 149307. DOI: 10.1016/j.bbabio.2024.149307.
The mouse metabolic phenotyping center (MMPC) live consortium: an NIH resource for in vivo characterization of mouse models of diabetes and obesityLaughlin M, McIndoe R, Adams S, Araiza R, Ayala J, Kennedy L, Lanoue L, Lantier L, Macy J, Malabanan E, McGuinness O, Perry R, Port D, Qi N, Elias C, Shulman G, Wasserman D, Lloyd K. The mouse metabolic phenotyping center (MMPC) live consortium: an NIH resource for in vivo characterization of mouse models of diabetes and obesity. Mammalian Genome 2024, 35: 485-496. PMID: 39191872, PMCID: PMC11522164, DOI: 10.1007/s00335-024-10067-y.
Glucagon promotes increased hepatic mitochondrial oxidation and pyruvate carboxylase flux in humans with fatty liver diseasePetersen K, Dufour S, Mehal W, Shulman G. Glucagon promotes increased hepatic mitochondrial oxidation and pyruvate carboxylase flux in humans with fatty liver disease. Cell Metabolism 2024, 36: 2359-2366.e3. PMID: 39197461, PMCID: PMC11612994, DOI: 10.1016/j.cmet.2024.07.023.
Association of Race and Ethnicity with Prescriptions for Continuous Glucose Monitoring Systems Among a National Sample of Veterans with Diabetes on Insulin TherapyLipska K, Oladele C, Zawack K, Gulanski B, Mutalik P, Reaven P, Lynch J, Lee K, Shih M, Lee J, Aslan M. Association of Race and Ethnicity with Prescriptions for Continuous Glucose Monitoring Systems Among a National Sample of Veterans with Diabetes on Insulin Therapy. Diabetes Technology & Therapeutics 2024, 26: 908-917. PMID: 39177775, DOI: 10.1089/dia.2024.0152.
Phosphoenolpyruvate carboxykinase-2 (PCK2) is a therapeutic target in triple-negative breast cancerGunasekharan V, Lin H, Marczyk M, Rios-Hoyo A, Campos G, Shan N, Ahmed M, Umlauf S, Gareiss P, Raaisa R, Williams R, Cardone R, Siebel S, Kibbey R, Surovtseva Y, Pusztai L. Phosphoenolpyruvate carboxykinase-2 (PCK2) is a therapeutic target in triple-negative breast cancer. Breast Cancer Research And Treatment 2024, 208: 657-671. PMID: 39177932, DOI: 10.1007/s10549-024-07462-z.
Small molecule inhibition of glycogen synthase I reduces muscle glycogen content and improves biomarkers in a mouse model of Pompe diseaseGaspar R, Sakuma I, Nasiri A, Hubbard B, LaMoia T, Leitner B, Tep S, Xi Y, Green E, Ullman J, Petersen K, Shulman G. Small molecule inhibition of glycogen synthase I reduces muscle glycogen content and improves biomarkers in a mouse model of Pompe disease. AJP Endocrinology And Metabolism 2024, 327: e524-e532. PMID: 39171753, PMCID: PMC11482269, DOI: 10.1152/ajpendo.00175.2024.
"SafetyNet": Evaluation of a Recovery Coach and Paramedic Intervention Following Naloxone Resuscitation From an Opioid Overdose.Joseph D, Brokowski C, D'Onofrio G, Bogucki S, McGovern J, Allen R, Dziura J, Cone D, Pantalon M. "SafetyNet": Evaluation of a Recovery Coach and Paramedic Intervention Following Naloxone Resuscitation From an Opioid Overdose. Substance Use & Addiction Journal 2024, 29767342241266412. PMID: 39171791, DOI: 10.1177/29767342241266412.
Evolving Concepts in Pathophysiology, Screening, and Prevention of Type 1 Diabetes: Report of Diabetes Mellitus Interagency Coordinating Committee Workshop.Greenbaum C, Nepom G, Wood-Heickman L, Wherrett D, DiMeglio L, Herold K, Krischer J. Evolving Concepts in Pathophysiology, Screening, and Prevention of Type 1 Diabetes: Report of Diabetes Mellitus Interagency Coordinating Committee Workshop. Diabetes 2024, 73: 1780-1790. PMID: 39167668, PMCID: PMC11493760, DOI: 10.2337/dbi24-0020.
Cytosolic calcium regulates hepatic mitochondrial oxidation, intrahepatic lipolysis, and gluconeogenesis via CAMKII activationLaMoia T, Hubbard B, Guerra M, Nasiri A, Sakuma I, Kahn M, Zhang D, Goodman R, Nathanson M, Sancak Y, Perelis M, Mootha V, Shulman G. Cytosolic calcium regulates hepatic mitochondrial oxidation, intrahepatic lipolysis, and gluconeogenesis via CAMKII activation. Cell Metabolism 2024, 36: 2329-2340.e4. PMID: 39153480, PMCID: PMC11446666, DOI: 10.1016/j.cmet.2024.07.016.
Teplizumab induces persistent changes in the antigen‐specific repertoire in individuals at‐risk for type 1 diabetesLledó-Delgado A, Preston-Hurlburt P, Currie S, Clark P, Linsley P, Long S, Liu C, Koroleva G, Martins A, Tsang J, Herold K. Teplizumab induces persistent changes in the antigen‐specific repertoire in individuals at‐risk for type 1 diabetes. Journal Of Clinical Investigation 2024, 134: e177492. PMID: 39137044, PMCID: PMC11405034, DOI: 10.1172/jci177492.
Item Response Theory Quantifies the Relationship Between Improvements in Serum Phosphate and Patient‐Reported Outcomes in Adults With X‐Linked HypophosphatemiaMehta K, Gosselin N, Insogna K, Barriere O, Quattrocchi E, Hruska M, Marsteller D. Item Response Theory Quantifies the Relationship Between Improvements in Serum Phosphate and Patient‐Reported Outcomes in Adults With X‐Linked Hypophosphatemia. Clinical Pharmacology & Therapeutics 2024, 116: 1343-1351. PMID: 39129452, DOI: 10.1002/cpt.3406.
Global deletion of G protein‐coupled receptor 55 impairs glucose homeostasis during obesity by reducing insulin secretion and β‐cell turnoverLiu B, Ruz‐Maldonado I, Persaud S. Global deletion of G protein‐coupled receptor 55 impairs glucose homeostasis during obesity by reducing insulin secretion and β‐cell turnover. Diabetes Obesity And Metabolism 2024, 26: 4591-4601. PMID: 39113250, DOI: 10.1111/dom.15816.
Semaglutide and cardiovascular outcomes in patients with obesity and prevalent heart failure: a prespecified analysis of the SELECT trialDeanfield J, Verma S, Scirica B, Kahn S, Emerson S, Ryan D, Lingvay I, Colhoun H, Plutzky J, Kosiborod M, Hovingh G, Hardt-Lindberg S, Frenkel O, Weeke P, Rasmussen S, Goudev A, Lang C, Urina-Triana M, Pietilä M, Lincoff A, Investigators S, Abe M, Abhaichand R, Abhayaratna W, Abhyankar A, Abidin I, Assi H, Mendoza J, Adas M, Agaiby J, Agarwal D, Agha M, Ahmed A, Ahtiainen P, Aigner E, Ajay N, Ali N, Al-Karadsheh A, Allison R, Allison D, Alpenidze D, Altuntas Y, Al-Zoebi A, Ambuj R, Amerena J, Anderson R, Ando T, Andrews R, Antonova E, Appel K, Arantes F, Araz M, Arbel Y, León J, Argyrakopoulou G, Ariani M, Mendoza M, Arif A, Arneja J, Aroda V, Aronne L, Arstall M, Asamoah N, Asanin M, Audish H, Avram R, Badat A, Badiu C, Bakdash W, Bakiner O, Bandezi V, Bang L, Bansal S, Baranyai M, Barbarash O, Barber M, Barnum O, Rochette G, Bashkin A, Baum S, Bays H, Ruiz A, Beckowski M, Beerachee Y, Bellary S, Belousova L, Berk M, Bernstein M, Berra C, Beshay I, Bhagwat A, Bhan A, Biggs W, Billings L, Bitar F, Block B, Bo S, Bogdanski P, Bolshakova O, Boshchenko A, Bosworth H, Lopez R, Bôttcher M, Bourgeois R, Brautigam D, Breton C, Broadley A, Brockmyre A, Brodie S, Bucci M, Budincevic H, Budoff M, Buffman B, Buljubasic N, Buranapin S, Burgess L, Burguera B, Buriakovska O, Buscemi S, Busch R, Buse J, Buynak R, Byrne M, Caceaune E, Bonfanti A, Calinescu C, Call R, Varzic S, Cannon K, Capehorn M, Cariou B, Carr J, Carrillo-Jimenez R, Casas M, Castro A, Celik A, Cercato C, Cermak O, Y J, Chacon C, Chaicha-Brom T, Chandra S, Chettibi M, Chevts J, Christopher J, Chrustowski W, Cif A, Clark R, Clark W, Clifford P, Coetzee K, Cogni G, Colao A, Colquhoun D, Concha M, Condit J, Constance C, Constantin C, Constantinescu S, Corbett C, Cornett G, Correia M, Cortinovis F, Cosma D, Creely S, Cross D, Curtis B, Czochra W, Daboul N, Dagdelen S, D'agostino R, Dang C, Datta S, Davuluri A, Dawood S, De Jong D, De La Cuesta C, De Los Rios Ibarra M, De Pablo C, De Pauw M, Dela Llana A, Delibasic M, Delic-Brkljacic D, Demicheli T, Denger R, Desai D, Desai P, Desouza C, Dicker D, Djenic N, Dobson S, Doi M, Doran J, Dorman R, Dotta F, Dukes C, Duronto E, Durst R, Dvoryashina I, Ebrahim I, Eggebrecht H, Egstrup K, Ekinci E, Eliasson B, Eliasson K, Enache G, Enculescu D, English P, Ermakova P, Ershova O, Ezaki H, Ezhov M, Farias E, Farias J, Farsky P, Ferreira D, Filteau P, Finneran M, Folkens E, Fonseca A, Fonseca L, Fordan S, Fourie N, França S, Franco D, Franek E, Friedman K, Frittitta L, Froer M, Fuckar K, Fujii K, Fujita R, Fukushima Y, Fulat M, Fulwani M, Gajos G, Galyavich A, Gambill M, Gandotra D, Winston G, Hernandez P, Reza R, Garg N, Garg S, Garvey W, Garza J, Gatta-Cherifi B, Gelev V, Geller S, Geohas J, Georgiev B, Ghazi A, Gilbert M, Gilinskaya O, Gislason G, Yavuz D, Albarrán O, Gordeev I, Gorton S, Goudev A, Valderhaug T, 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Khlevchuk T, Khoo J, Kiatchoosakun S, Kinoshita N, Kinoshita M, Kitamura R, Kiyosue A, Klavina I, Klein E, Klimsa Z, Klonoff D, Klug E, Kobalava Z, Kodera S, Koga T, Kokkinos A, Koleckar P, Könyves L, Koren M, Kormann A, Kostner K, Kreutzmann K, Krishinan S, Krishnasamy S, Krivosheeva I, Kruljac I, Kubicki T, Kuchar L, Kujawiak M, Kunishige H, Kurtinecz M, Lisboa H, Kushnir M, Kyyak Y, Lace A, Lakka T, Lalic N, Lalic K, Lambadiari V, Lanaras L, Lang C, Langlois M, Lash J, Latkovskis G, Lau D, Soto J, Le Roux C, Ledesma G, Lee L, Lee T, Lee K, Lehrke M, Leite S, Leksycka A, Lenzmeier T, Leonetti F, Leonidova V, Lepor N, Leung M, Levchenko O, Levins P, Levy L, Lewis M, Liberopoulos E, Liberty I, Lindholm C, Lingvay I, Linhart A, Liu M, Liu J, Lofton H, Logemann T, Lombaard J, Lombard L, Lorraine R, Lovell C, Ludvik B, Lukaszewicz M, Lupkovics G, Lupovitch S, Lupu S, Lynch M, Lysak Z, Lysenko T, Maeda H, Maeda I, Mæng M, Mahajan A, Maher V, Maia L, Makotoko E, Malavazos A, Malecha J, 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Wongcharoen W, Wozniak I, Wu C, Wyatt N, Wynne A, Yamaguchi H, Yamasaki M, Yazici D, Yeh H, Yotov Y, Yuan Q, Zacher J, Zagrebelnaya O, Zaidman C, Zalevskaya A, Zarich S, Zatelli M, Zeller H, Zhdanova E, Zornitzki T, Zrazhevskiy K, Zykov M, Lincoff A, Ryan D, Colhoun H, Deanfield J, Emerson S, Kahn S, Kushner R, Plutzky J, Brown-Frandsen K, Hovingh G, Hardt-Lindberg S, Tornøe C. Semaglutide and cardiovascular outcomes in patients with obesity and prevalent heart failure: a prespecified analysis of the SELECT trial. The Lancet 2024, 404: 773-786. PMID: 39181597, DOI: 10.1016/s0140-6736(24)01498-3.
A kidney-hypothalamus axis promotes compensatory glucose production in response to glycosuriaFaniyan T, Zhang X, Morgan D, Robles J, Bathina S, Brookes P, Rahmouni K, Perry R, Chhabra K. A kidney-hypothalamus axis promotes compensatory glucose production in response to glycosuria. ELife 2024, 12 DOI: 10.7554/elife.91540.4.
A kidney-hypothalamus axis promotes compensatory glucose production in response to glycosuriaFaniyan T, Zhang X, Morgan D, Robles J, Bathina S, Brookes P, Rahmouni K, Perry R, Chhabra K. A kidney-hypothalamus axis promotes compensatory glucose production in response to glycosuria. ELife 2024, 12: rp91540. PMID: 39082939, PMCID: PMC11290820, DOI: 10.7554/elife.91540.
Checkpoint Inhibitor-Induced Autoimmune Diabetes: An Autoinflammatory Disease.Quandt Z, Perdigoto A, Anderson M, Herold K. Checkpoint Inhibitor-Induced Autoimmune Diabetes: An Autoinflammatory Disease. Cold Spring Harbor Perspectives In Medicine 2024, a041603. PMID: 39038853, DOI: 10.1101/cshperspect.a041603.
Effects of dapagliflozin according to QRS duration across the spectrum of left ventricular ejection fraction: An analysis of DAPA‐HF and DELIVERAbdin A, Kondo T, Böhm M, Jhund P, Claggett B, Vaduganathan M, Hernandez A, Lam C, Inzucchi S, Martinez F, de Boer R, Desai A, Køber L, Sabatine M, Petersson M, Bachus E, Solomon S, McMurray J, Committees and Investigators O. Effects of dapagliflozin according to QRS duration across the spectrum of left ventricular ejection fraction: An analysis of DAPA‐HF and DELIVER. European Journal Of Heart Failure 2024, 26: 1952-1963. PMID: 39016033, DOI: 10.1002/ejhf.3350.
O-GlcNAc modification in endothelial cells modulates adiposity via fat absorption from the intestine in miceOhgaku S, Ida S, Ohashi N, Morino K, Ishikado A, Yanagimachi T, Murata K, Sato D, Ugi S, Nasiri A, Shulman G, Maegawa H, Kume S, Fujita Y. O-GlcNAc modification in endothelial cells modulates adiposity via fat absorption from the intestine in mice. Heliyon 2024, 10: e34490. PMID: 39130439, PMCID: PMC11315187, DOI: 10.1016/j.heliyon.2024.e34490.
COVID-19Fernando S. COVID-19. 2024, 409-415. DOI: 10.4324/9781003300991-41.
Modeling of drinking and driving behaviors among adolescents and young adults in the United States: Complexities and Intervention outcomesHosseinichimeh N, MacDonald R, Li K, Fell J, Haynie D, Simons-Morton B, Banz B, Camenga D, Iannotti R, Curry L, Dziura J, Andersen D, Vaca F. Modeling of drinking and driving behaviors among adolescents and young adults in the United States: Complexities and Intervention outcomes. Social Science & Medicine 2024, 354: 117087. PMID: 39043064, PMCID: PMC11334945, DOI: 10.1016/j.socscimed.2024.117087.
Extended-Release 7-Day Injectable Buprenorphine for Patients With Minimal to Mild Opioid WithdrawalD’Onofrio G, Herring A, Perrone J, Hawk K, Samuels E, Cowan E, Anderson E, McCormack R, Huntley K, Owens P, Martel S, Schactman M, Lofwall M, Walsh S, Dziura J, Fiellin D. Extended-Release 7-Day Injectable Buprenorphine for Patients With Minimal to Mild Opioid Withdrawal. JAMA Network Open 2024, 7: e2420702. PMID: 38976265, PMCID: PMC11231806, DOI: 10.1001/jamanetworkopen.2024.20702.
Erratum to “An update on clinical presentation and responses to therapy of patients with hereditary hypophosphatemic rickets with hypercalciuria (HHRH).” Kidney International 2023;105:1058–1076Zhu Z, Bo-Ran Ho B, Chen A, Amrhein J, Apetrei A, Carpenter T, Lazaretti-Castro M, Colazo J, McCrystal Dahir K, Geßner M, Gurevich E, Heier C, Simmons J, Hunley T, Hoppe B, Jacobsen C, Kouri A, Ma N, Majumdar S, Molin A, Nokoff N, Ott S, Peña H, Santos F, Tebben P, Topor L, Deng Y, Bergwitz C. Erratum to “An update on clinical presentation and responses to therapy of patients with hereditary hypophosphatemic rickets with hypercalciuria (HHRH).” Kidney International 2023;105:1058–1076. Kidney International 2024, 106: 159. PMID: 38906648, PMCID: PMC11610493, DOI: 10.1016/j.kint.2024.05.005.
Ending Weight Stigma to Advance Health EquityPearl R, Donze L, Rosas L, Agurs-Collins T, Baskin M, Breland J, Byker Shanks C, Cooksey Stowers K, Johnson S, Lee B, Martin M, Mujuru P, Odoms-Young A, Panza E, Pronk N, Calicutt K, Nadglowski J, Nece P, Tedder M, Chow L, Krishnamurti H, Jay M, Xi D, Jastreboff A, Stanford F. Ending Weight Stigma to Advance Health Equity. American Journal Of Preventive Medicine 2024, 67: 785-791. PMID: 38945180, DOI: 10.1016/j.amepre.2024.06.021.
Bile acid-gut microbiota imbalance in cholestasis and its long-term effect in miceYang X, Xu Y, Li J, Ran X, Gu Z, Song L, Zhang L, Wen L, Ji G, Wang R. Bile acid-gut microbiota imbalance in cholestasis and its long-term effect in mice. MSystems 2024, 9: e00127-24. PMID: 38934542, PMCID: PMC11265269, DOI: 10.1128/msystems.00127-24.
Both enantiomers of β-aminoisobutyric acid BAIBA regulate Fgf23 via MRGPRD receptor by activating distinct signaling pathways in osteocytesSakamoto E, Kitase Y, Fitt A, Zhu Z, Awad K, Brotto M, White K, Welc S, Bergwitz C, Bonewald L. Both enantiomers of β-aminoisobutyric acid BAIBA regulate Fgf23 via MRGPRD receptor by activating distinct signaling pathways in osteocytes. Cell Reports 2024, 43: 114397. PMID: 38935499, PMCID: PMC11350516, DOI: 10.1016/j.celrep.2024.114397.
Effect of Semaglutide on Regression and Progression of Glycemia in People With Overweight or Obesity but Without Diabetes in the SELECT TrialKahn S, Deanfield J, Jeppesen O, Emerson S, Boesgaard T, Colhoun H, Kushner R, Lingvay I, Burguera B, Gajos G, Horn D, Hramiak I, Jastreboff A, Kokkinos A, Maeng M, Matos A, Tinahones F, Lincoff A, Ryan D, Investigators S. Effect of Semaglutide on Regression and Progression of Glycemia in People With Overweight or Obesity but Without Diabetes in the SELECT Trial. Diabetes Care 2024, 47: 1350-1359. PMID: 38907683, PMCID: PMC11282386, DOI: 10.2337/dc24-0491.
1571-P: CIDEB and CGI-58 Regulate Liver Lipid Droplet Size with Cholesterol Content, Linking to Inflammation and Fibrosis in Metabolic Dysfunction–Associated SteatohepatitisSAKUMA I, GASPAR R, NASIRI A, KAHN M, ZHENG J, GUERRA M, YIMLAMAI D, MURRAY S, PERELIS M, BARNES W, VATNER D, PETERSEN K, SAMUEL V, SHULMAN G. 1571-P: CIDEB and CGI-58 Regulate Liver Lipid Droplet Size with Cholesterol Content, Linking to Inflammation and Fibrosis in Metabolic Dysfunction–Associated Steatohepatitis. Diabetes 2024, 73 DOI: 10.2337/db24-1571-p.
292-OR: Coenzyme A Synthase Knockdown Alleviates Metabolic Dysfunction–Associated Steatohepatitis via Decreasing Cholesterol in Liver Lipid DropletsSAKUMA I, GASPAR R, NASIRI A, KAHN M, GUERRA M, YIMLAMAI D, MURRAY S, PERELIS M, BARNES W, VATNER D, PETERSEN K, SAMUEL V, SHULMAN G. 292-OR: Coenzyme A Synthase Knockdown Alleviates Metabolic Dysfunction–Associated Steatohepatitis via Decreasing Cholesterol in Liver Lipid Droplets. Diabetes 2024, 73 DOI: 10.2337/db24-292-or.
1577-P: CIDEB Knockdown Promotes Increased Hepatic Mitochondrial Fat Oxidation and Reverses Hepatic Steatosis and Hepatic Insulin Resistance by the PKCε-Insulin Receptor Kinase PathwayZHENG J, NASIRI A, GASPAR R, HUBBARD B, SAKUMA I, MA X, MURRAY S, PERELIS M, BARNES W, SAMUEL V, PETERSEN K, SHULMAN G. 1577-P: CIDEB Knockdown Promotes Increased Hepatic Mitochondrial Fat Oxidation and Reverses Hepatic Steatosis and Hepatic Insulin Resistance by the PKCε-Insulin Receptor Kinase Pathway. Diabetes 2024, 73 DOI: 10.2337/db24-1577-p.
1583-P: Measuring Mitochondrial Metabolism In Vivo with [1,2-13C2]-L-Glutamine Mass IsotopomersSIEBEL S, CARDONE R, MASON G, KIBBEY R. 1583-P: Measuring Mitochondrial Metabolism In Vivo with [1,2-13C2]-L-Glutamine Mass Isotopomers. Diabetes 2024, 73 DOI: 10.2337/db24-1583-p.
1574-P: Catecholamine-Induced Adipose Lipolysis Drives Hepatic Steatosis in Pnpla3I148M Knockin MicePRAKASH GOLLA J, SUH R, PAOLELLA L, STROBER J, ZHANG F, PHILBRICK W, VATNER D. 1574-P: Catecholamine-Induced Adipose Lipolysis Drives Hepatic Steatosis in Pnpla3I148M Knockin Mice. Diabetes 2024, 73 DOI: 10.2337/db24-1574-p.
315-OR: Task-Induced Alterations in the Salience Network amongst Patients with Type 1 DiabetesSANCHEZ RANGEL E, BELFORT-DEAGUIAR R, LACADIE C, CHUNG T, SCHEINOST D, MASON G, HWANG J. 315-OR: Task-Induced Alterations in the Salience Network amongst Patients with Type 1 Diabetes. Diabetes 2024, 73 DOI: 10.2337/db24-315-or.
1637-P: TLC-6740, a Liver-Targeted Mitochondrial Protonophore, Increases Energy Expenditure and Lipid Utilization in Obese MiceSRODA N, VIJAYAKUMAR A, MURAKAMI E, WENG S, SHULMAN G, MYERS R, SUBRAMANIAN M. 1637-P: TLC-6740, a Liver-Targeted Mitochondrial Protonophore, Increases Energy Expenditure and Lipid Utilization in Obese Mice. Diabetes 2024, 73 DOI: 10.2337/db24-1637-p.
68-OR: Influence of the Type 1 Diabetes Genetic Risk Score on Response to Immunotherapies for Type 1 Diabetes PreventionREDONDO M, BUNDY B, PARIKH H, YOU L, TRIOLO T, FERRAT L, TEMPLEMAN E, TOSUR M, STECK A, GOTTLIEB P, ONENGUT-GUMUSCU S, RICH S, ORAM R, HEROLD K, KRISCHER J. 68-OR: Influence of the Type 1 Diabetes Genetic Risk Score on Response to Immunotherapies for Type 1 Diabetes Prevention. Diabetes 2024, 73 DOI: 10.2337/db24-68-or.
899-P: Combinations of the Mitochondrial Protonophore TLC-6740 and/or the ACC2 Inhibitor TLC-3595 Provide Additive Glycemic Benefits to Semaglutide (SEMA) in db/db MiceVIJAYAKUMAR A, SRODA N, MURAKAMI E, WENG S, MYERS R, SUBRAMANIAN M, SHULMAN G. 899-P: Combinations of the Mitochondrial Protonophore TLC-6740 and/or the ACC2 Inhibitor TLC-3595 Provide Additive Glycemic Benefits to Semaglutide (SEMA) in db/db Mice. Diabetes 2024, 73 DOI: 10.2337/db24-899-p.
1886-LB: Safety, PK, and Preliminary Efficacy of the Liver-Targeted Mitochondrial Protonophore TLC-6740—A Phase 1 StudyGANE E, HUSS R, SUR J, MURAKAMI E, WENG S, KIRBY B, SHAH A, SHULMAN G, SUBRAMANIAN M, VIJAYAKUMAR A, MYERS R. 1886-LB: Safety, PK, and Preliminary Efficacy of the Liver-Targeted Mitochondrial Protonophore TLC-6740—A Phase 1 Study. Diabetes 2024, 73 DOI: 10.2337/db24-1886-lb.
692-P: Work or Wellness? Examining Challenges of Low Wage Workers with Type 2 DiabetesSCHLESINGER P, ASANTE P, LIPSKA K, KEENE D. 692-P: Work or Wellness? Examining Challenges of Low Wage Workers with Type 2 Diabetes. Diabetes 2024, 73 DOI: 10.2337/db24-692-p.
1734-P: ADP Privation of Human Beta-Cell Mitochondria by Pyruvate KinaseRUZ-MALDONADO I, CARDONE R, KIBBEY R. 1734-P: ADP Privation of Human Beta-Cell Mitochondria by Pyruvate Kinase. Diabetes 2024, 73 DOI: 10.2337/db24-1734-p.
155-OR: Genetic Variation and Time to Progression in TN10 (Teplizumab)MICHALEK D, ONENGUT-GUMUSCU S, CHEN W, BRUSKO T, STECK A, GOTTLIEB P, ORAM R, KRISCHER J, PARIKH H, REDONDO M, HEROLD K, RICH S. 155-OR: Genetic Variation and Time to Progression in TN10 (Teplizumab). Diabetes 2024, 73 DOI: 10.2337/db24-155-or.

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