Peter Natale Peduzzi PhD

Professor of Public Health (Biostatistics); Director, Yale Center for Analytical Sciences (YCAS)

Biographical Info

Peter is professor of biostatistics at YSPH and director of YCAS and the BSR of YCC. He was recruited to establish YCAS and bring all biostatistics under one umbrella at YMS. He also serves on the Executive Committee and Protocol Review Committee for YCC. Dr. Peduzzi has more than 30 years’ experience in the design, conduct and analysis of clinical trials and comparative effectiveness studies. Before coming to Yale he was the Director of the VA Cooperative Studies Program Coordinating Center at the VA Connecticut Healthcare System, West Haven, CT for more than a decade and is still affiliated with this center. His primary research interests have focused on the efficient design and analysis of comparative effectiveness clinical trials and geriatric studies.


International Activity

  • Antiretrovirals, Options in Management (OPTIMA)
    Canada; United Kingdom (2008 - 2008)
    OPTIMA was a randomized clinical trial coordinated by the VA Cooperative Studies Program Coordinating Center at West Haven, CT, which is a 2x2 factorial trial of salvage therapy evaluating mega-HAART versus standard HARRT and treatment interruption versus no interruption in 368 patients with advanced HIV disease. OPTIMA was a tri-national collaboration among the VA, UK Medical Research Council and the Canadian Institutes for Health Research. The trial was completed in 2008.
  • Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluations (COURAGE)
    Canada (2005 - 2006)
    COURAGE was a randomized clinical trial coordinated by the VA Cooperative Studies Program Coordinating Center at West Haven, CT, which evaluated maximal medical therapy plus angioplasty versus maximum medical therapy alone in patients with stable coronary disease. The trial enrolled 2287 patients from 50 U.S and Canadian medical centers. The trial was completed in 2006 and published in the New England Journal of Medicine in 2007 (356: 1503-16)

Education & Training

Ph.D.
Yale University (1976)

Honors & Recognition

  • Fellow, Council on Epidemiology, American Heart Association
  • Fellow, American Statistical Association
  • Past President, Society for Clinical Trials
  • VA Research Career Scientist Award
  • Fellow, Society for Clinical Trials

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