Leadership


Kleinstein, Steven H

Associate Professor of Pathology

Associate Professor of Pathology and of Immunobiology

Biography

Dr. Steven Kleinstein received a B.A.S. in Computer Science from the University of Pennsylvania and a Ph.D. in Computer Science from Princeton University. He is currently an Associate Professor of Pathology and Immunobiology at the Yale School of Medicine, and a member of the Interdepartmental Program in Computational Biology and Bioinformatics, and the Human Translational Immunology Program. While formally trained in Computer Science, Dr. Kleinstein has been working on...

Dr. Steven Kleinstein received a B.A.S. in Computer Science from the University of Pennsylvania and a Ph.D. in Computer Science from Princeton University. He is currently an Associate Professor of Pathology and Immunobiology at the Yale School of Medicine, and a member of the Interdepartmental Program in Computational Biology and Bioinformatics, and the Human Translational Immunology Program. While formally trained in Computer Science, Dr. Kleinstein has been working on applications in immunology for nearly 20 years. His research combines techniques from dynamic modeling, systems biology and bioinformatics to capitalize on recent advances in immune profiling methods to characterize diverse states of the human immune system (in health and disease, and following infection and vaccination). B cell adaptive immunity and somatic hypermutation have been a particular focus of his work. Recently, his lab has been developing computational methods for the processing and analysis of large-scale B cell immunoglobulin sequencing data sets generated by next-generation sequencing technologies. Another significant research focus involves the human immune response to influenza infection and vaccination.

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Members

Amezquita, Robert A.

Graduate Student

Avey, Stefan

Graduate Student

Cui, Ang

Ph.D. Candidate

Fermin, Damian

Software Engineer

Gadala-Maria , Daniel Francis

Ph.D student in Computational Biology and Bioinformatics

Gupta, Namita

Ph.D. Candidate

Meng, Hailong

Senior Bioinformatics Scientist

Research Interests: Hailong's research interests include data analysis on high-throughput data such as Next Generation Sequencing (NGS) data and microarray data, database management and implementation, and software development in bioinformatics and computational biology fields to discover novel biology.

Sarantis, Demetrios

Postdoctoral Associate in Pathology

Research Interests: Ontology Engineering, Models for Data Interchange on the Web, Data Integration

Vander Heiden, Jason

Graduate Student

Wu, Jialiang

Postdoctoral Fellow in Anesthesiology (Medical Informatics)

Former Lab Members

Students and Postdocs

  • Christopher Bolen - Postdoctoral Associate, Mark Davis Lab, Stanford University
  • Jamie L. Duke - Postdoctoral Associate, Manos Lab, CHOP, University of Pennsylvania
  • Uri Hershberg - Assistant Professor, Drexel University
  • Juilee Thakar - Assistant Professor, University of Rochester
  • Gur Yaari - Assistant Professor, Bar-Illan University

Summer Students and Visiting Faculty

  • Alexandra Signoriello (Ursinus College), Summer 2012
  • Emad Ramadan (KFUPM, Saudi Arabia), Summer 2012 
  • Nailen Matschke (Hopkins School, CT), Summer 2011 
  • Jacob Stern (Brown University), Summer 2010

Research Staff

  • Susanna Marquez - Pearlman Lab, York University
  • Alexander Karpikov - Morgan Stanley, New York