Tormod Rogne, MD, PhD
Assistant Professor Adjunct of Epidemiology (Chronic Diseases)Cards
Contact Info
Yale School of Public Health
Yale Center for Perinatal, Pediatric and Environmental Epidemiology, One Church Street, 6th Floor
New Haven, CT 06510
United States
About
Titles
Assistant Professor Adjunct of Epidemiology (Chronic Diseases)
Biography
Dr. Rogne is a medical doctor and researcher who focuses on perinatal epidemiology. Some of the ongoing projects includes evaluating how climate change affects pregnancy, the role of modifiable risk factors on reproductive health and adverse pregnancy outcomes, and how being born preterm affects the risk of cardiovascular and infectious diseases in adulthood. To tackle clinically relevant questions and providing robust results, he applies modern methods ranging from negative controls and inverse-probability weighting to genetic epidemiological methods and genome-wide association analyses. Dr. Rogne places emphasis on using high-quality data, in particular by use of data from population based cohorts and national registries.
Appointments
Chronic Disease Epidemiology
Assistant Professor AdjunctPrimary
Other Departments & Organizations
Education & Training
- Postdoctoral Scholar
- Norwegian University of Science and Technology, NTNU (2021)
- Fulbright Scholar
- Yale School of Public Health (2019)
- Residency
- Akershus University Hospital and Ski Municipality (2018)
- PhD
- Norwegian University of Science and Technology, NTNU (2016)
- MD
- Norwegian University of Science and Technology, NTNU (2015)
Research
Overview
Medical Subject Headings (MeSH)
- View Lab Website
Yale Center for Perinatal, Pediatric and Environmental Epidemiology
Research at a Glance
Yale Co-Authors
Publications Timeline
Research Interests
Andrew DeWan, PhD, MPH
Xiaomei Ma, PhD
Rong Wang, PhD
Mark Sleeman, PhD
Bohao Wu
Joshua Warren, PhD
Publications
2024
High ambient temperature in pregnancy and risk of childhood acute lymphoblastic leukaemia: an observational study
Rogne T, Wang R, Wang P, Deziel N, Metayer C, Wiemels J, Chen K, Warren J, Ma X. High ambient temperature in pregnancy and risk of childhood acute lymphoblastic leukaemia: an observational study. The Lancet Planetary Health 2024, 8: e506-e514. PMID: 38969477, PMCID: PMC11260908, DOI: 10.1016/s2542-5196(24)00121-9.Peer-Reviewed Original ResearchAltmetricMeSH Keywords and ConceptsConceptsRisk of childhood acute lymphoblastic leukemiaChildhood acute lymphoblastic leukemiaAcute lymphoblastic leukemiaLymphoblastic leukemiaLatino childrenNon-Latino white childrenAssociated with risk of adverse pregnancy outcomesCalifornia Cancer RegistryRisk of acute lymphoblastic leukemiaCalifornia birth recordsRisk of adverse pregnancy outcomesPre-pregnancy periodAssociated with riskBayesian meta-regressionNational Institutes of HealthCancer RegistryCases of childhood acute lymphoblastic leukemiaNational Center for Advancing Translational SciencesAdverse pregnancy outcomesAcute lymphoblastic leukemia casesInstitutes of HealthInvestigation of mechanistic pathwaysBirth recordsGestational weeks 8Pre-pregnancyA Genome-wide Association Study of Susceptibility to Upper Urinary Tract Infections
Flatby H, Ravi A, Liyanarachi K, Afset J, Rasheed H, Brumpton B, Hveem K, Åsvold B, DeWan A, Solligård E, Damås J, Rogne T. A Genome-wide Association Study of Susceptibility to Upper Urinary Tract Infections. The Journal Of Infectious Diseases 2024, jiae231. PMID: 38713594, DOI: 10.1093/infdis/jiae231.Peer-Reviewed Original ResearchCitationsAltmetricConceptsGenome-wide association studiesMichigan Genomics InitiativeAssociation studiesUpper UTIMendelian randomizationMR analysisUpper urinary tract infectionRisk factorsPotential causal risk factorsCardiometabolic risk factorsModifiable risk factorsSex-stratified analysesCausal risk factorUrinary tract infectionGenome-wideFemale-only analysisGenetic lociPotential causal relationshipGenome InitiativeHealth StudyUK BiobankHLA-DQA2LociTract infectionsSmoking scoreChronic kidney disease and risk of bloodstream infections and sepsis: a 17-year follow-up of the population-based Trøndelag Health Study in Norway
Liyanarachi K, Mohus R, Rogne T, Gustad L, Åsvold B, Romundstad S, Solligård E, Hallan S, Damås J. Chronic kidney disease and risk of bloodstream infections and sepsis: a 17-year follow-up of the population-based Trøndelag Health Study in Norway. Infection 2024, 1-11. PMID: 38679665, DOI: 10.1007/s15010-024-02265-2.Peer-Reviewed Original ResearchAltmetricConceptsHazard ratioHazard ratio of deathChronic kidney diseaseCohort studyPopulation-based cohort studyNorwegian HUNT studyAlbumin-creatinine ratioTarget risk factorsAssociation of chronic kidney diseaseLoss of healthProspective cohort studyHUNT StudyHealth StudySystolic blood pressureSmoking statusKidney diseaseHospital admissionMedian follow-up timeGeneral populationRisk of bloodstream infectionImprove preventionFollow-up timeIncreased riskNormal albumin excretionRisk factorsPotential Selection Bias in Preterm Infant Mortality Study
Rogne T, Wu B, Hawley N. Potential Selection Bias in Preterm Infant Mortality Study. JAMA Pediatrics 2024, 178: 205-206. PMID: 38109083, DOI: 10.1001/jamapediatrics.2023.5582.Peer-Reviewed Original ResearchAltmetricMediating Factors in the Association of Maternal Educational Level With Pregnancy Outcomes
Rogne T, Gill D, Liew Z, Shi X, Stensrud V, Nilsen T, Burgess S. Mediating Factors in the Association of Maternal Educational Level With Pregnancy Outcomes. JAMA Network Open 2024, 7: e2351166. PMID: 38206626, PMCID: PMC10784860, DOI: 10.1001/jamanetworkopen.2023.51166.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsMeSH KeywordsBirth WeightCholesterolCohort StudiesDiabetes Mellitus, Type 2Educational StatusFemaleGenome-Wide Association StudyHumansHyperemesis GravidarumInfant, NewbornLipoproteins, HDLMediation AnalysisMendelian Randomization AnalysisPre-EclampsiaPregnancyPregnancy OutcomePregnancy, EctopicPremature BirthConceptsCardiometabolic risk factorsBody mass indexOffspring birth weightEducational attainmentMendelian randomizationHigh-density lipoprotein cholesterol levelsSystolic blood pressureInverse variance-weighted methodModifiable cardiometabolic risk factorsPregnancy outcomesCohort studyLipoprotein cholesterol levelsMR-Egger regressionMass indexUnivariable MR analysisEffects of educational attainmentAssociated with increased risk of adverse pregnancy outcomesPublic health interventionsMaternal education levelLower educational attainmentRisk factorsRisk of adverse pregnancy outcomesGenome-wide association studiesAssociated with increased riskBirth weight
2023
Influence of birth weight on later life cardiovascular structure, function and disease: unpacking influences from direct genetic effects versus intrauterine programming
Ardissino M, Slob E, Rayes B, Morley A, Raisi-Estabragh Z, De Marvao A, Williamson C, Rogne T, Burgess S, Ng F. Influence of birth weight on later life cardiovascular structure, function and disease: unpacking influences from direct genetic effects versus intrauterine programming. European Heart Journal 2023, 44: ehad655.2377. DOI: 10.1093/eurheartj/ehad655.2377.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseFetal genetic effectsLow ejection fractionSystolic blood pressureBody mass indexBirth weightArtery diseaseAtrial fibrillationCardiovascular diseaseHigh riskMendelian randomisationEjection fractionBlood pressureMass indexRisk factorsGestational age-adjusted birth weightCardiac structureAge-adjusted birth weightHigher systolic blood pressureLater-life cardiovascular diseaseCardinal risk factorCardiometabolic risk factorsHigh birth weightLife cardiovascular diseaseBody surface areaPharmacologic and Genetic Downregulation of Proprotein Convertase Subtilisin/Kexin Type 9 and Survival From Sepsis
Lawler P, Manvelian G, Coppi A, Damask A, Cantor M, Ferreira M, Paulding C, Banerjee N, Li D, Jorgensen S, Attre R, Carey D, Krebs K, Milani L, Hveem K, Damås J, Solligård E, Stender S, Tybjærg-Hansen A, Nordestgaard B, Hernandez-Beeftink T, Rogne T, Flores C, Villar J, Walley K, Liu V, Fohner A, Lotta L, Kyratsous C, Sleeman M, Scemama M, DelGizzi R, Pordy R, Horowitz J, Baras A, Martin G, Steg P, Schwartz G, Szarek M, Goodman S. Pharmacologic and Genetic Downregulation of Proprotein Convertase Subtilisin/Kexin Type 9 and Survival From Sepsis. Critical Care Explorations 2023, 5: e0997. PMID: 37954898, PMCID: PMC10635596, DOI: 10.1097/cce.0000000000000997.Peer-Reviewed Original ResearchCitationsAltmetricConceptsProprotein convertase subtilisin/kexin type 9Convertase subtilisin/kexin type 9Subtilisin/kexin type 9Human cohort studiesODYSSEY OUTCOMESCohort studyType 9Isotype-matched controlExperimental murine modelSepsis ratePCSK9 inhibitionPCSK9 inhibitorsSepsis complicationsSepsis mortalitySepsis outcomeImproved survivalBacterial sepsisClinical outcomesBloodstream clearanceSepsis modelClinical trialsOdds ratioCardiovascular diseasePretreatment settingSepsis diagnosisAssociation of Genetically Predicted Insomnia With Risk of Sepsis
Thorkildsen M, Gustad L, Mohus R, Burgess S, Nilsen T, Damås J, Rogne T. Association of Genetically Predicted Insomnia With Risk of Sepsis. JAMA Psychiatry 2023, 80: 1061-1065. PMID: 37556136, PMCID: PMC10413214, DOI: 10.1001/jamapsychiatry.2023.2717.Peer-Reviewed Original ResearchCitationsAltmetricBirth weight influences cardiac structure, function, and disease risk: evidence of a causal association
Ardissino M, Morley A, Slob E, Schuermans A, Rayes B, Raisi-Estabragh Z, de Marvao A, Burgess S, Rogne T, Honigberg M, Ng F. Birth weight influences cardiac structure, function, and disease risk: evidence of a causal association. European Heart Journal 2023, 45: 443-454. PMID: 37738114, PMCID: PMC10849320, DOI: 10.1093/eurheartj/ehad631.Peer-Reviewed Original ResearchCitationsAltmetricConceptsLow birth weightAdverse intrauterine environmentCoronary artery diseaseBirth weightIntrauterine environmentCardiac structureArtery diseaseFoetal effectsCardiovascular disease prevention strategiesDisease riskAdverse cardiac structureCardiovascular disease riskCommon pregnancy complicationLower stroke volumeDisease prevention strategiesMendelian randomization studyBenjamini-Hochberg correctionPregnancy complicationsIschemic strokeHeart failureAtrial fibrillationCardiometabolic diseasesIntrauterine influencesStroke volumeCardiovascular diseaseGestational age at birth and hospitalisations for infections among individuals aged 0–50 years in Norway: a longitudinal, register-based, cohort study
Nilsen S, Valand J, Rogne T, Asheim A, Yin W, Metsälä J, Opdahl S, Døllner H, Damås J, Kajantie E, Solligård E, Sandin S, Risnes K. Gestational age at birth and hospitalisations for infections among individuals aged 0–50 years in Norway: a longitudinal, register-based, cohort study. EClinicalMedicine 2023, 62: 102108. PMID: 37538542, PMCID: PMC10393616, DOI: 10.1016/j.eclinm.2023.102108.Peer-Reviewed Original ResearchCitationsAltmetricConceptsInfectious Diseases GroupRespiratory tract infectionsLower gestational age groupGestational age groupsGestational ageDisease groupCohort studyUniversity HospitalRate ratioAge groupsInfectious diseasesHigher hospitalisation risksHospitalisation rate ratiosNationwide hospital dataRisk of hospitalisationSt. Olavs University HospitalSigrid Jusélius FoundationYear of birthHospitalisation riskLate pretermPreterm birthSecondary outcomesTract infectionsPrimary outcomeChildhood infections
Academic Achievements and Community Involvement
activity Advisor
Peer Review Groups and Grant Study SectionsThe Journal of the Norwegian Medical AssociationMedical research advisorDetails11/06/2017 - Presentactivity Research and teaching at Yale School of Public Health
ResearchDetails07/01/2021 - PresentNew Haven, CT, United Statesactivity Research collaboration with the Norwegian Institute of Public Health
ResearchDetails09/25/2020 - PresentOslo, Oslo, Norwayhonor Fulbright Scholarship
International AwardDetails12/07/2017Norwayhonor Tom Wilhelmsen Foundation’s Research Stipend
International AwardDetails06/03/2013Norway
Links & Media
News
- July 03, 2024
Ambient heat during pregnancy linked to increased risk of childhood cancer
- August 09, 2023
Genetic study confirms potential link between insomnia and sepsis risk
- May 02, 2022
Snapshots
- September 28, 2021
New YSPH Faculty: Tormod Rogne
Get In Touch
Contacts
Yale School of Public Health
Yale Center for Perinatal, Pediatric and Environmental Epidemiology, One Church Street, 6th Floor
New Haven, CT 06510
United States