Featured Publications
Association Between the Decline in Pneumococcal Disease in Unimmunized Adults and Vaccine-Derived Protection Against Colonization in Toddlers and Preschool-Aged Children
Weinberger DM, Pitzer VE, Regev-Yochay G, Givon-Lavi N, Dagan R. Association Between the Decline in Pneumococcal Disease in Unimmunized Adults and Vaccine-Derived Protection Against Colonization in Toddlers and Preschool-Aged Children. American Journal Of Epidemiology 2018, 188: 160-168. PMID: 30462150, PMCID: PMC6321804, DOI: 10.1093/aje/kwy219.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsAgedCarrier StateChild, PreschoolFemaleHeptavalent Pneumococcal Conjugate VaccineHumansImmunity, HerdInfantIsraelMaleMiddle AgedNasopharynxPneumococcal InfectionsSerogroupSocioeconomic FactorsVaccination CoverageYoung AdultConceptsInvasive pneumococcal diseaseUnimmunized adultsPneumococcal diseaseVaccine-associated immunityVaccine-derived protectionVaccine-targeted serotypesNationwide surveillance studyPrevalence of colonizationUnvaccinated adultsPneumococcal carriagePreschool aged childrenVaccine uptakeColonization prevalenceGroup of childrenVaccination coverageEmergency departmentSurveillance studyDisease ratesTrajectory of declineAge rangeAdultsAged childrenChildrenSerotypesVaccine
2015
Association Between Local Pediatric Vaccination Rates and Patterns of Pneumococcal Disease in Adults
Pingali SC, Warren JL, Mead AM, Sharova N, Petit S, Weinberger DM. Association Between Local Pediatric Vaccination Rates and Patterns of Pneumococcal Disease in Adults. The Journal Of Infectious Diseases 2015, 213: 509-515. PMID: 26310307, PMCID: PMC4721904, DOI: 10.1093/infdis/jiv431.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overChildChild, PreschoolConnecticutHeptavalent Pneumococcal Conjugate VaccineHumansInfantMiddle AgedPneumococcal InfectionsSerotypingStreptococcus pneumoniaeVaccinationYoung AdultConceptsInvasive pneumococcal diseasePneumococcal diseaseIPD casesPopulation-based surveillance systemZip code level dataAdult IPD casesDoses of PCV7Effectiveness of PCVsPediatric vaccination ratesVaccination of childrenState immunization registryZip codesLogistic regression modelsPCV7 serotypesHigher proportionVaccination ratesImmunization registryDisease patternsDiseaseAdultsPCV7PCVSerotypesChildrenDosesAssociation between Respiratory Syncytial Virus Activity and Pneumococcal Disease in Infants: A Time Series Analysis of US Hospitalization Data
Weinberger DM, Klugman KP, Steiner CA, Simonsen L, Viboud C. Association between Respiratory Syncytial Virus Activity and Pneumococcal Disease in Infants: A Time Series Analysis of US Hospitalization Data. PLOS Medicine 2015, 12: e1001776. PMID: 25562317, PMCID: PMC4285401, DOI: 10.1371/journal.pmed.1001776.Peer-Reviewed Original ResearchMeSH KeywordsHeptavalent Pneumococcal Conjugate VaccineHospitalizationHumansIncidenceInfantInfant, NewbornPneumonia, PneumococcalPrevalenceRespiratory Syncytial Virus InfectionsRespiratory Syncytial Virus, HumanSeasonsUnited StatesConceptsRespiratory syncytial virusPneumococcal pneumoniaRate of hospitalizationPneumococcal diseaseHospitalization dataSeven-valent pneumococcal conjugate vaccineBacterial infectionsRespiratory syncytial virus activityLaboratory-confirmed dataPneumococcal pneumonia hospitalizationsPneumococcal conjugate vaccineIntroduction of PCV7Secondary bacterial infectionState Inpatient DatabasesPoisson regression modelsRSV hospitalizationPCV7 introductionPneumonia hospitalizationsConjugate vaccineInpatient DatabaseSyncytial virusPneumococcal septicemiaPneumonia casesEpidemic timingHospitalization
2011
Serotype replacement in disease after pneumococcal vaccination
Weinberger DM, Malley R, Lipsitch M. Serotype replacement in disease after pneumococcal vaccination. The Lancet 2011, 378: 1962-1973. PMID: 21492929, PMCID: PMC3256741, DOI: 10.1016/s0140-6736(10)62225-8.Peer-Reviewed Original ResearchMeSH KeywordsCarrier StateHeptavalent Pneumococcal Conjugate VaccineHumansPneumococcal InfectionsPneumococcal VaccinesSerotypingStreptococcus pneumoniaeConceptsNon-vaccine serotypesSerotype replacementPneumococcal diseaseHeptavalent pneumococcal conjugate vaccinePneumococcal conjugate vaccineImportant public health benefitsBenefits of vaccinationPublic health benefitsDisease surveillance systemsNVT carriagePneumococcal vaccinationSurveillance biasesConjugate vaccineVaccine serotypesCarriage prevalencePneumococcal serotypesAsymptomatic carriersCarriage dataDiseaseVaccinationHealth benefitsLow invasivenessPrevalenceSerotypesCarriage