Publications

• CD31 as a probable responding and gate-keeping protein of the blood-brain barrier and the risk of Alzheimer's disease.Zhang Z, Gan Q, Han J, Tao Q, Qiu WQ, Madri JA. J Cereb Blood Flow Metab. 2023 Jul; 2023 Apr 12. PMID: 37051650.
• A Static Self-Directed Method for Generating Brain Organoids from Human Embryonic Stem Cells.Boisvert EM, Means RE, Michaud M, Thomson JJ, Madri JA, Katz SG. J Vis Exp. 2020 Mar 4; 2020 Mar 4. PMID: 32202516.
• Somatic PRKAR1A mutation in sporadic atrial myxoma with cerebral parenchymal metastases: a case report.Roque A, Kimbrough T, Traner C, Baehring JM, Huttner A, Adams J, Canosa S, Sklar J, Madri JA. J Med Case Rep. 2019 Dec 25; 2019 Dec 25. PMID: 31874650.
• Minocycline mitigates the effect of neonatal hypoxic insult on human brain organoids.Boisvert EM, Means RE, Michaud M, Madri JA, Katz SG. Cell Death Dis. 2019 Apr 11; 2019 Apr 11. PMID: 30975982.
• MMP-2: A modulator of neuronal precursor activity and cognitive and motor behaviors.Li Q, Michaud M, Shankar R, Canosa S, Schwartz M, Madri JA. Behav Brain Res. 2017 Aug 30; 2017 Jun 27. PMID: 28666838.
• As human lung microvascular endothelia achieve confluence, src family kinases are activated, and tyrosine-phosphorylated p120 catenin physically couples NEU1 sialidase to CD31.Hyun SW, Liu A, Liu Z, Lillehoj EP, Madri JA, Reynolds AB, Goldblum SE. Cell Signal. 2017 Jul; 2017 Mar 24. PMID: 28343945.
• -NOD Mice Having a Lyn Tyrosine Kinase Mutation Exhibit Abnormal Neutrophil Chemotaxis.Wu Y, Hannigan M, Zhan L, Madri JA, Huang CK. J Cell Physiol. 2017 Jul; 2017 Mar 27. PMID: 27591397.
• CD44 Promotes Inflammation and Extracellular Matrix Production During Arteriovenous Fistula Maturation.Kuwahara G, Hashimoto T, Tsuneki M, Yamamoto K, Assi R, Foster TR, Hanisch JJ, Bai H, Hu H, Protack CD, Hall MR, Schardt JS, Jay SM, Madri JA, Kodama S, Dardik A. Arterioscler Thromb Vasc Biol. 2017 Jun; 2017 Apr 27. PMID: 28450292.
• Increased Oxidative Stress and Hypoxia Inducible Factor-1 Expression during Arteriovenous Fistula Maturation.Sadaghianloo N, Yamamoto K, Bai H, Tsuneki M, Protack CD, Hall MR, Declemy S, Hassen-Khodja R, Madri J, Dardik A. Ann Vasc Surg. 2017 May; 2017 Feb 3. PMID: 28163173.
• The role of endothelial HIF-1 αin the response to sublethal hypoxia in C57BL/6 mouse pups.Li Q, Michaud M, Park C, Huang Y, Couture R, Girodano F, Schwartz ML, Madri JA. Lab Invest. 2017 Apr; 2017 Jan 16. PMID: 28092362.
• Targeted proteomics effectively quantifies differences between native lung and detergent-decellularized lung extracellular matrices.Calle EA, Hill RC, Leiby KL, Le AV, Gard AL, Madri JA, Hansen KC, Niklason LE. Acta Biomater. 2016 Dec; 2016 Sep 29. PMID: 27693690.
• CD44 Influences Fibroblast Behaviors Via Modulation of Cell-Cell and Cell-Matrix Interactions, Affecting Survivin and Hippo Pathways.Tsuneki M, Madri JA. J Cell Physiol. 2016 Mar. PMID: 26248063.
• ENPP1-Fc prevents mortality and vascular calcifications in rodent model of generalized arterial calcification of infancy.Albright RA, Stabach P, Cao W, Kavanagh D, Mullen I, Braddock AA, Covo MS, Tehan M, Yang G, Cheng Z, Bouchard K, Yu ZX, Thorn S, Wang X, Folta-Stogniew EJ, Negrete A, Sinusas AJ, Shiloach J, Zubal G, Madri JA, De La Cruz EM, Braddock DT. Nat Commun. 2015 Dec 1; 2015 Dec 1. PMID: 26624227.
• Modulation of Sox10, HIF-1α, Survivin, and YAP by Minocycline in the Treatment of Neurodevelopmental Handicaps following Hypoxic Insult.Li Q, Tsuneki M, Krauthammer M, Couture R, Schwartz M, Madri JA. Am J Pathol. 2015 Sep; 2015 Jul 22. PMID: 26209807.
• A hydrogel-endothelial cell implant mimics infantile hemangioma: modulation by survivin and the Hippo pathway.Tsuneki M, Hardee S, Michaud M, Morotti R, Lavik E, Madri JA. Lab Invest. 2015 Jul; 2015 May 11. PMID: 25961170.
• Disturbed shear stress reduces Klf2 expression in arterial-venous fistulae in vivo.Yamamoto K, Protack CD, Kuwahara G, Tsuneki M, Hashimoto T, Hall MR, Assi R, Brownson KE, Foster TR, Bai H, Wang M, Madri JA, Dardik A. Physiol Rep. 2015 Mar. PMID: 25780089.
• Temporal regulation of venous extracellular matrix components during arteriovenous fistula maturation.Hall MR, Yamamoto K, Protack CD, Tsuneki M, Kuwahara G, Assi R, Brownson KE, Bai H, Madri JA, Dardik A. J Vasc Access. 2015 Mar-Apr; 2014 Sep 8. PMID: 25262757.
• Adhesion molecule-mediated hippo pathway modulates hemangioendothelioma cell behavior.Tsuneki M, Madri JA. Mol Cell Biol. 2014 Dec; 2014 Sep 29. PMID: 25266662.
• Stratified control of IGF-I expression by hypoxia and stress hormones in osteoblasts.McCarthy TL, Yun Z, Madri JA, Centrella M. Gene. 2014 Apr 10; 2014 Jan 15. PMID: 24440782.
• NEU1 sialidase regulates the sialylation state of CD31 and disrupts CD31-driven capillary-like tube formation in human lung microvascular endothelia.Lee C, Liu A, Miranda-Ribera A, Hyun SW, Lillehoj EP, Cross AS, Passaniti A, Grimm PR, Kim BY, Welling PA, Madri JA, DeLisser HM, Goldblum SE. J Biol Chem. 2014 Mar 28; 2014 Feb 18. PMID: 24550400.
• CD44 regulation of endothelial cell proliferation and apoptosis via modulation of CD31 and VE-cadherin expression.Tsuneki M, Madri JA. J Biol Chem. 2014 Feb 28; 2014 Jan 14. PMID: 24425872.
• The mouse aortocaval fistula recapitulates human arteriovenous fistula maturation.Yamamoto K, Protack CD, Tsuneki M, Hall MR, Wong DJ, Lu DY, Assi R, Williams WT, Sadaghianloo N, Bai H, Miyata T, Madri JA, Dardik A. Am J Physiol Heart Circ Physiol. 2013 Dec; 2013 Oct 4. PMID: 24097429.
• Modeling the neurovascular niche: unbiased transcriptome analysis of the murine subventricular zone in response to hypoxic insult.Li Q, Canosa S, Flynn K, Michaud M, Krauthammer M, Madri JA. PLoS One. 2013; 2013 Oct 11. PMID: 24146847.
• CD44 regulates vascular endothelial barrier integrity via a PECAM-1 dependent mechanism.Flynn KM, Michaud M, Canosa S, Madri JA. Angiogenesis. 2013 Jul; 2013 Mar 17. PMID: 23504212.
• CD44 deficiency contributes to enhanced experimental autoimmune encephalomyelitis: a role in immune cells and vascular cells of the blood-brain barrier.Flynn KM, Michaud M, Madri JA. Am J Pathol. 2013 Apr; 2013 Feb 12. PMID: 23416161.
• Brain regional angiogenic potential at the neurovascular unit during normal aging.Murugesan N, Demarest TG, Madri JA, Pachter JS. Neurobiol Aging. 2012 May; 2011 Oct 21. PMID: 22019053.
• Phosphorus-31 MRI of hard and soft solids using quadratic echo line-narrowing.Frey MA, Michaud M, VanHouten JN, Insogna KL, Madri JA, Barrett SE. Proc Natl Acad Sci U S A. 2012 Apr 3; 2012 Mar 19. PMID: 22431609.
• Short term interactions with long term consequences: modulation of chimeric vessels by neural progenitors.Williams C, Rauch MF, Michaud M, Robinson R, Xu H, Madri J, Lavik E. PLoS One. 2012; 2012 Dec 27. PMID: 23300890.
• Characterization of the natural history of extracellular matrix production in tissue-engineered vascular grafts during neovessel formation.Naito Y, Williams-Fritze M, Duncan DR, Church SN, Hibino N, Madri JA, Humphrey JD, Shinoka T, Breuer CK. Cells Tissues Organs. 2012; 2011 Oct 12. PMID: 21996715.
• A critical role for macrophages in neovessel formation and the development of stenosis in tissue-engineered vascular grafts.Hibino N, Yi T, Duncan DR, Rathore A, Dean E, Naito Y, Dardik A, Kyriakides T, Madri J, Pober JS, Shinoka T, Breuer CK. FASEB J. 2011 Dec; 2011 Aug 24. PMID: 21865316.
• Cyclic strain delays the expression of tissue factor induced by thrombin in human umbilical vein endothelial cells.Yamashita N, Abe R, Nixon AM, Rochier AL, Madri JA, Sumpio BE. Int J Angiol. 2011 Sep. PMID: 22942631.
• Varying effects of hemodynamic forces on tissue factor RNA expression in human endothelial cells.Abe R, Yamashita N, Rochier A, Nixon A, Abe R, Madri JA, Sumpio BE. J Surg Res. 2011 Sep; 2011 May 4. PMID: 21592524.
• Laminar shear, but not orbital shear, has a synergistic effect with thrombin stimulation on tissue factor expression in human umbilical vein endothelial cells.Rochier A, Nixon A, Yamashita N, Abe R, Abe R, Madri JA, Sumpio BE. J Vasc Surg. 2011 Aug; 2011 Mar 2. PMID: 21367569.
• GSK-3β: a signaling pathway node modulating neural stem cell and endothelial cell interactions.Li Q, Michaud M, Canosa S, Kuo A, Madri JA. Angiogenesis. 2011 May; 2011 Jan 21. PMID: 21253820.
• Pulsatile to-fro flow induces greater and sustained expression of tissue factor RNA in HUVEC than unidirectional laminar flow.Abe R, Yamashita N, Rochier A, Abe R, Nixon A, Madri JA, Sumpio BE. Am J Physiol Heart Circ Physiol. 2011 Apr; 2011 Jan 21. PMID: 21257914.
• Myometrial wound healing post-Cesarean delivery in the MRL/MpJ mouse model of uterine scarring.Buhimschi CS, Zhao G, Sora N, Madri JA, Buhimschi IA. Am J Pathol. 2010 Jul; 2010 May 20. PMID: 20489145.
• An implantable vascularized protein gel construct that supports human fetal hepatoblast survival and infection by hepatitis C virus in mice.Harding MJ, Lepus CM, Gibson TF, Shepherd BR, Gerber SA, Graham M, Paturzo FX, Rahner C, Madri JA, Bothwell AL, Lindenbach BD, Pober JS. PLoS One. 2010 Apr 1; 2010 Apr 1. PMID: 20376322.
• Insights into monocyte-driven osteoclastogenesis and its link with hematopoiesis: regulatory roles of PECAM-1 (CD31) and SHP-1.Wu Y, Madri J. Crit Rev Immunol. 2010. PMID: 21083524.
• Strain differences in behavioral and cellular responses to perinatal hypoxia and relationships to neural stem cell survival and self-renewal: Modeling the neurovascular niche.Li Q, Liu J, Michaud M, Schwartz ML, Madri JA. Am J Pathol. 2009 Nov; 2009 Oct 8. PMID: 19815710.
• Modeling the neurovascular niche: implications for recovery from CNS injury.Madri JA. J Physiol Pharmacol. 2009 Oct. PMID: 20083857.
• VEGF-A and Semaphorin3A: modulators of vascular sympathetic innervation.Long JB, Jay SM, Segal SS, Madri JA. Dev Biol. 2009 Oct 1; 2009 Jul 23. PMID: 19631637.
• Characterization of RAGE, HMGB1, and S100beta in inflammation-induced preterm birth and fetal tissue injury.Buhimschi CS, Baumbusch MA, Dulay AT, Oliver EA, Lee S, Zhao G, Bhandari V, Ehrenkranz RA, Weiner CP, Madri JA, Buhimschi IA. Am J Pathol. 2009 Sep; 2009 Aug 13. PMID: 19679874.
• Using proteomics in perinatal and neonatal sepsis: hopes and challenges for the future.Buhimschi CS, Bhandari V, Han YW, Dulay AT, Baumbusch MA, Madri JA, Buhimschi IA. Curr Opin Infect Dis. 2009 Jun. PMID: 19395960.
• Bone marrow monocyte PECAM-1 deficiency elicits increased osteoclastogenesis resulting in trabecular bone loss.Wu Y, Tworkoski K, Michaud M, Madri JA. J Immunol. 2009 Mar 1. PMID: 19234161.
• Proteomic-based detection of a protein cluster dysregulated during cardiovascular development identifies biomarkers of congenital heart defects.Nath AK, Krauthammer M, Li P, Davidov E, Butler LC, Copel J, Katajamaa M, Oresic M, Buhimschi I, Buhimschi C, Snyder M, Madri JA. PLoS One. 2009; 2009 Jan 19. PMID: 19156209.
• Engineering angiogenesis following spinal cord injury: a coculture of neural progenitor and endothelial cells in a degradable polymer implant leads to an increase in vessel density and formation of the blood-spinal cord barrier.Rauch MF, Hynes SR, Bertram J, Redmond A, Robinson R, Williams C, Xu H, Madri JA, Lavik EB. Eur J Neurosci. 2009 Jan. PMID: 19120441.
• Fibroblast-type reticular stromal cells regulate the lymph node vasculature.Chyou S, Ekland EH, Carpenter AC, Tzeng TC, Tian S, Michaud M, Madri JA, Lu TT. J Immunol. 2008 Sep 15. PMID: 18768843.
• Matrix metalloproteinase 9 facilitates West Nile virus entry into the brain.Wang P, Dai J, Bai F, Kong KF, Wong SJ, Montgomery RR, Madri JA, Fikrig E. J Virol. 2008 Sep; 2008 Jul 16. PMID: 18632868.
• Targeted imaging of hypoxia-induced integrin activation in myocardium early after infarction.Kalinowski L, Dobrucki LW, Meoli DF, Dione DP, Sadeghi MM, Madri JA, Sinusas AJ. J Appl Physiol (1985). 2008 May; 2008 Mar 20. PMID: 18356482.
• Modeling the neurovascular niche: murine strain differences mimic the range of responses to chronic hypoxia in the premature newborn.Li Q, Michaud M, Stewart W, Schwartz M, Madri JA. J Neurosci Res. 2008 May 1. PMID: 18092360.
• Leptin affects endocardial cushion formation by modulating EMT and migration via Akt signaling cascades.Nath AK, Brown RM, Michaud M, Sierra-Honigmann MR, Snyder M, Madri JA. J Cell Biol. 2008 Apr 21; 2008 Apr 14. PMID: 18411306.
• TNF-alpha induces MMP2 gelatinase activity and MT1-MMP expression in an in vitro model of nucleus pulposus tissue degeneration.Séguin CA, Pilliar RM, Madri JA, Kandel RA. Spine (Phila Pa 1976). 2008 Feb 15. PMID: 18277865.
• Co-culture of primary neural progenitor and endothelial cells in a macroporous gel promotes stable vascular networks in vivo.Rauch MF, Michaud M, Xu H, Madri JA, Lavik EB. J Biomater Sci Polym Ed. 2008. PMID: 18973724.
• Differential effects of shear stress and cyclic strain on Sp1 phosphorylation by protein kinase Czeta modulates membrane type 1-matrix metalloproteinase in endothelial cells.Kim JI, Cordova AC, Hirayama Y, Madri JA, Sumpio BE. Endothelium. 2008 Jan-Feb. PMID: 18568943.
• PECAM-1: a multifaceted regulator of megakaryocytopoiesis.Wu Y, Welte T, Michaud M, Madri JA. Blood. 2007 Aug 1; 2007 Apr 5. PMID: 17412889.
• MAPKAPK2-mediated LSP1 phosphorylation and FMLP-induced neutrophil polarization.Wu Y, Zhan L, Ai Y, Hannigan M, Gaestel M, Huang CK, Madri JA. Biochem Biophys Res Commun. 2007 Jun 22; 2007 Apr 24. PMID: 17481585.
• Loss of MMP-2 disrupts skeletal and craniofacial development and results in decreased bone mineralization, joint erosion and defects in osteoblast and osteoclast growth.Mosig RA, Dowling O, DiFeo A, Ramirez MC, Parker IC, Abe E, Diouri J, Aqeel AA, Wylie JD, Oblander SA, Madri J, Bianco P, Apte SS, Zaidi M, Doty SB, Majeska RJ, Schaffler MB, Martignetti JA. Hum Mol Genet. 2007 May 1; 2007 Mar 30. PMID: 17400654.
• Juvenile hyaline fibromatosis and infantile systemic hyalinosis overlap associated with a novel mutation in capillary morphogenesis protein-2 gene.Antaya RJ, Cajaiba MM, Madri J, Lopez MA, Ramirez MC, Martignetti JA, Reyes-Múgica M. Am J Dermatopathol. 2007 Feb. PMID: 17284973.
• PECAM-1 modulates thrombin-induced tissue factor expression on endothelial cells.Zhang JJ, Kelm RJ, Biswas P, Kashgarian M, Madri JA. J Cell Physiol. 2007 Feb. PMID: 17111362.
• Modeling the neurovascular niche: VEGF- and BDNF-mediated cross-talk between neural stem cells and endothelial cells: an in vitro study.Li Q, Ford MC, Lavik EB, Madri JA. J Neurosci Res. 2006 Dec. PMID: 17061253.
• Gamma delta T cells facilitate adaptive immunity against West Nile virus infection in mice.Wang T, Gao Y, Scully E, Davis CT, Anderson JF, Welte T, Ledizet M, Koski R, Madri JA, Barrett A, Yin Z, Craft J, Fikrig E. J Immunol. 2006 Aug 1. PMID: 16849493.
• PECAM-1 affects GSK-3beta-mediated beta-catenin phosphorylation and degradation.Biswas P, Canosa S, Schoenfeld D, Schoenfeld J, Li P, Cheas LC, Zhang J, Cordova A, Sumpio B, Madri JA. Am J Pathol. 2006 Jul. PMID: 16816383.
• The roles of nitric oxide in murine cardiovascular development.Nath AK, Madri JA. Dev Biol. 2006 Apr 1; 2006 Jan 25. PMID: 16442519.
• Effects of a novel tylophorine analog on collagen-induced arthritis through inhibition of the innate immune response.You X, Pan M, Gao W, Shiah HS, Tao J, Zhang D, Koumpouras F, Wang S, Zhao H, Madri JA, Baker D, Cheng YC, Yin Z. Arthritis Rheum. 2006 Mar. PMID: 16508970.
• A macroporous hydrogel for the coculture of neural progenitor and endothelial cells to form functional vascular networks in vivo.Ford MC, Bertram JP, Hynes SR, Michaud M, Li Q, Young M, Segal SS, Madri JA, Lavik EB. Proc Natl Acad Sci U S A. 2006 Feb 21; 2006 Feb 10. PMID: 16473951.
• Neutrophils lacking platelet-endothelial cell adhesion molecule-1 exhibit loss of directionality and motility in CXCR2-mediated chemotaxis.Wu Y, Stabach P, Michaud M, Madri JA. J Immunol. 2005 Sep 15. PMID: 16148090.
• Noninvasive imaging of angiogenesis with a 99mTc-labeled peptide targeted at alphavbeta3 integrin after murine hindlimb ischemia.Hua J, Dobrucki LW, Sadeghi MM, Zhang J, Bourke BN, Cavaliere P, Song J, Chow C, Jahanshad N, van Royen N, Buschmann I, Madri JA, Mendizabal M, Sinusas AJ. Circulation. 2005 Jun 21; 2005 Jun 13. PMID: 15956134.
• Role of C5 in the development of airway inflammation, airway hyperresponsiveness, and ongoing airway response.Peng T, Hao L, Madri JA, Su X, Elias JA, Stahl GL, Squinto S, Wang Y. J Clin Invest. 2005 Jun; 2005 May 12. PMID: 15902311.
• Identification of the regions of PECAM-1 involved in beta- and gamma-catenin associations.Biswas P, Zhang J, Schoenfeld JD, Schoenfeld D, Gratzinger D, Canosa S, Madri JA. Biochem Biophys Res Commun. 2005 Apr 22. PMID: 15766557.
• MAPKs (ERK1/2, p38) and AKT can be phosphorylated by shear stress independently of platelet endothelial cell adhesion molecule-1 (CD31) in vascular endothelial cells.Sumpio BE, Yun S, Cordova AC, Haga M, Zhang J, Koh Y, Madri JA. J Biol Chem. 2005 Mar 25; 2005 Jan 24. PMID: 15668248.
• Enhanced susceptibility to endotoxic shock and impaired STAT3 signaling in CD31-deficient mice.Carrithers M, Tandon S, Canosa S, Michaud M, Graesser D, Madri JA. Am J Pathol. 2005 Jan. PMID: 15632011.
• MMP-2 null mice exhibit an early onset and severe experimental autoimmune encephalomyelitis due to an increase in MMP-9 expression and activity.Esparza J, Kruse M, Lee J, Michaud M, Madri JA. FASEB J. 2004 Nov. PMID: 15522913.
• A null mutation of Hhex results in abnormal cardiac development, defective vasculogenesis and elevated Vegfa levels.Hallaq H, Pinter E, Enciso J, McGrath J, Zeiss C, Brueckner M, Madri J, Jacobs HC, Wilson CM, Vasavada H, Jiang X, Bogue CW. Development. 2004 Oct. PMID: 15459110.
• Paracrine and autocrine functions of brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) in brain-derived endothelial cells.Kim H, Li Q, Hempstead BL, Madri JA. J Biol Chem. 2004 Aug 6; 2004 May 28. PMID: 15169782.
• Noninvasive imaging of myocardial angiogenesis following experimental myocardial infarction.Meoli DF, Sadeghi MM, Krassilnikova S, Bourke BN, Giordano FJ, Dione DP, Su H, Edwards DS, Liu S, Harris TD, Madri JA, Zaret BL, Sinusas AJ. J Clin Invest. 2004 Jun. PMID: 15199403.
• Nitric oxide modulates murine yolk sac vasculogenesis and rescues glucose induced vasculopathy.Nath AK, Enciso J, Kuniyasu M, Hao XY, Madri JA, Pinter E. Development. 2004 May. PMID: 15128676.
• Histamine inhibits conducted vasodilation through endothelium-derived NO production in arterioles of mouse skeletal muscle.Payne GW, Madri JA, Sessa WC, Segal SS. FASEB J. 2004 Feb. PMID: 14769822.
• Transcriptional up-regulation of endothelial cell matrix metalloproteinase-2 in response to extracellular cues involves GATA-2.Han X, Boyd PJ, Colgan S, Madri JA, Haas TL. J Biol Chem. 2003 Nov 28; 2003 Sep 25. PMID: 14512418.
• PECAM-1: old friend, new partners.Ilan N, Madri JA. Curr Opin Cell Biol. 2003 Oct. PMID: 14519385.
• Vascular endothelial growth factor expression, beta-catenin tyrosine phosphorylation, and endothelial proliferative behavior: a pathway for transformation?Ilan N, Tucker A, Madri JA. Lab Invest. 2003 Aug. PMID: 12920240.
• Platelet endothelial cell adhesion molecule-1 modulates endothelial cell motility through the small G-protein Rho.Gratzinger D, Canosa S, Engelhardt B, Madri JA. FASEB J. 2003 Aug. PMID: 12890700.
• Abolition of arteriolar dilation but not constriction to histamine in cremaster muscle of eNOS-/- mice.Payne GW, Madri JA, Sessa WC, Segal SS. Am J Physiol Heart Circ Physiol. 2003 Aug; 2003 Apr 10. PMID: 12689855.
• Maternal diabetes: effects on embryonic vascular development--a vascular endothelial growth factor-A-mediated process.Madri JA, Enciso J, Pinter E. Pediatr Dev Pathol. 2003 Jul-Aug. PMID: 14692647.
• PECAM-1 promotes beta-catenin accumulation and stimulates endothelial cell proliferation.Biswas P, Canosa S, Schoenfeld J, Schoenfeld D, Tucker A, Madri JA. Biochem Biophys Res Commun. 2003 Mar 28. PMID: 12646189.
• Lack of platelet endothelial cell adhesion molecule-1 attenuates foreign body inflammation because of decreased angiogenesis.Solowiej A, Biswas P, Graesser D, Madri JA. Am J Pathol. 2003 Mar. PMID: 12598328.
• Elevated glucose inhibits VEGF-A-mediated endocardial cushion formation: modulation by PECAM-1 and MMP-2.Enciso JM, Gratzinger D, Camenisch TD, Canosa S, Pinter E, Madri JA. J Cell Biol. 2003 Feb 17. PMID: 12591918.
• Platelet-endothelial cell adhesion molecule-1 modulates endothelial migration through its immunoreceptor tyrosine-based inhibitory motif.Gratzinger D, Barreuther M, Madri JA. Biochem Biophys Res Commun. 2003 Jan 31. PMID: 12535670.
• The evolving roles of cell surface proteases in health and disease: implications for developmental, adaptive, inflammatory, and neoplastic processes.Madri JA. Curr Top Dev Biol. 2003. PMID: 12696757.
• Disrupted synaptic development in the hypoxic newborn brain.Curristin SM, Cao A, Stewart WB, Zhang H, Madri JA, Morrow JS, Ment LR. Proc Natl Acad Sci U S A. 2002 Nov 26; 2002 Nov 15. PMID: 12438650.
• Transcription factor Sp1 phosphorylation induced by shear stress inhibits membrane type 1-matrix metalloproteinase expression in endothelium.Yun S, Dardik A, Haga M, Yamashita A, Yamaguchi S, Koh Y, Madri JA, Sumpio BE. J Biol Chem. 2002 Sep 20; 2002 Jul 1. PMID: 12093818.
• Cyclic strain stimulates early growth response gene product 1-mediated expression of membrane type 1 matrix metalloproteinase in endothelium.Yamaguchi S, Yamaguchi M, Yatsuyanagi E, Yun SS, Nakajima N, Madri JA, Sumpio BE. Lab Invest. 2002 Jul. PMID: 12118097.
• Paracrine and autocrine functions of neuronal vascular endothelial growth factor (VEGF) in the central nervous system.Ogunshola OO, Antic A, Donoghue MJ, Fan SY, Kim H, Stewart WB, Madri JA, Ment LR. J Biol Chem. 2002 Mar 29; 2002 Jan 3. PMID: 11777931.
• Altered vascular permeability and early onset of experimental autoimmune encephalomyelitis in PECAM-1-deficient mice.Graesser D, Solowiej A, Bruckner M, Osterweil E, Juedes A, Davis S, Ruddle NH, Engelhardt B, Madri JA. J Clin Invest. 2002 Feb. PMID: 11827998.
• Astrocyte-derived VEGF mediates survival and tube stabilization of hypoxic brain microvascular endothelial cells in vitro.Chow J, Ogunshola O, Fan SY, Li Y, Ment LR, Madri JA. Brain Res Dev Brain Res. 2001 Sep 23. PMID: 11557101.
• pp60(c-src) modulates microvascular endothelial phenotype and in vitro angiogenesis.Marx M, Warren SL, Madri JA. Exp Mol Pathol. 2001 Jun. PMID: 11417999.
• Focal adhesion kinase activates Stat1 in integrin-mediated cell migration and adhesion.Xie B, Zhao J, Kitagawa M, Durbin J, Madri JA, Guan JL, Fu XY. J Biol Chem. 2001 Jun 1; 2001 Feb 21. PMID: 11278462.
• Hyperglycemia-induced vasculopathy in the murine conceptus is mediated via reductions of VEGF-A expression and VEGF receptor activation.Pinter E, Haigh J, Nagy A, Madri JA. Am J Pathol. 2001 Apr. PMID: 11290536.
• Pecam-1 is a modulator of stat family member phosphorylation and localization: lessons from a transgenic mouse.Ilan N, Cheung L, Miller S, Mohsenin A, Tucker A, Madri JA. Dev Biol. 2001 Apr 1. PMID: 11254359.
• PECAM-1 shedding during apoptosis generates a membrane-anchored truncated molecule with unique signaling characteristics.Ilan N, Mohsenin A, Cheung L, Madri JA. FASEB J. 2001 Feb. PMID: 11156952.
• Matrix metalloproteinase activity is required for activity-induced angiogenesis in rat skeletal muscle.Haas TL, Milkiewicz M, Davis SJ, Zhou AL, Egginton S, Brown MD, Madri JA, Hudlicka O. Am J Physiol Heart Circ Physiol. 2000 Oct. PMID: 11009439.