2012
A Validated Prediction Tool for Initial Survivors of In-Hospital Cardiac Arrest
Chan PS, Spertus JA, Krumholz HM, Berg RA, Li Y, Sasson C, Nallamothu BK, Investigators F. A Validated Prediction Tool for Initial Survivors of In-Hospital Cardiac Arrest. JAMA Internal Medicine 2012, 172: 947-953. PMID: 22641228, PMCID: PMC3517176, DOI: 10.1001/archinternmed.2012.2050.Peer-Reviewed Original ResearchConceptsFavorable neurological survivalHospital cardiac arrestNeurological survivalCardiac arrestNeurological statusDerivation cohortValidation cohortInitial cardiac arrest rhythmIn-Hospital Cardiac ArrestBaseline neurological statusFavorable neurological statusGuidelines-Resuscitation registryCardiac arrest rhythmSevere neurological deficitsPulseless ventricular tachycardiaMultivariate logistic regressionSimple prediction toolRenal insufficiencyArrest rhythmNeurological deficitsHepatic insufficiencyMechanical ventilationMalignant diseaseVentricular tachycardiaInitial survivors
2008
Systolic Function as a Predictor of Mortality and Quality of Life in Long‐term Survivors with Heart Failure
McNamara R, Austin B, Wang Y, Smith G, Vaccarine V, Krumholz H. Systolic Function as a Predictor of Mortality and Quality of Life in Long‐term Survivors with Heart Failure. Clinical Cardiology 2008, 31: 119-124. PMID: 18383045, PMCID: PMC6653267, DOI: 10.1002/clc.20118.Peer-Reviewed Original ResearchConceptsQuality of lifeEjection fractionHeart failureLong-term survivorsFunctional declineSystolic functionKansas City Cardiomyopathy Questionnaire scoreModest survival advantageReduced ejection fractionDaily living scoreDisease-related qualityPredictors of mortalityHeart failure patientsClinical summary scoreLong-term survivalHigh mortality rateKCCQ scoresRenal insufficiencyFailure patientsLiving scoreDiabetes mellitusOverall mortalityPrimary outcomeLimitation scoresQOL scores
2005
Aspirin Use in Older Patients With Heart Failure and Coronary Artery Disease National Prescription Patterns and Relationship With Outcomes
Masoudi FA, Wolfe P, Havranek EP, Rathore SS, Foody JM, Krumholz HM. Aspirin Use in Older Patients With Heart Failure and Coronary Artery Disease National Prescription Patterns and Relationship With Outcomes. Journal Of The American College Of Cardiology 2005, 46: 955-962. PMID: 16168275, DOI: 10.1016/j.jacc.2004.07.062.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseHeart failureAspirin prescriptionAspirin useRenal insufficiencyLower riskLower unadjusted ratesNational prescription patternsUse of aspirinClustering of patientsEvidence of harmCause readmissionCoronary eventsOlder patientsPrescription patternsSecondary preventionArtery diseaseACE inhibitorsMultivariable analysisUnadjusted ratesHospital characteristicsTreatment benefitMedicare beneficiariesAspirinPatients
2003
Gender, age, and heart failure with preserved left ventricular systolic function
Masoudi FA, Havranek EP, Smith G, Fish RH, Steiner JF, Ordin DL, Krumholz HM. Gender, age, and heart failure with preserved left ventricular systolic function. Journal Of The American College Of Cardiology 2003, 41: 217-223. PMID: 12535812, DOI: 10.1016/s0735-1097(02)02696-7.Peer-Reviewed Original ResearchConceptsLeft ventricular systolic functionImpaired left ventricular systolic functionVentricular systolic functionHeart failureSystolic functionFemale genderDiagnosis of HFMedical chart abstractionCoronary artery diseasePrincipal discharge diagnosisAge 65 yearsMultivariable logistic regressionCross-sectional studyPotential confounding variablesRenal insufficiencyChart abstractionClinical characteristicsElderly patientsArtery diseaseEjection fractionPulmonary diseasePatient factorsAtrial fibrillationDischarge diagnosisPotential confounders
2002
Differences between African Americans and whites in the outcome of heart failure: Evidence for a greater functional decline in African Americans
Vaccarino V, Gahbauer E, Kasl SV, Charpentier PA, Acampora D, Krumholz HM. Differences between African Americans and whites in the outcome of heart failure: Evidence for a greater functional decline in African Americans. American Heart Journal 2002, 143: 1058-1067. PMID: 12075264, DOI: 10.1067/mhj.2002.122123.Peer-Reviewed Original ResearchMeSH KeywordsActivities of Daily LivingAgedAnalysis of VarianceBlack PeopleCohort StudiesFemaleHealth Services AccessibilityHeart FailureHospitalizationHumansIncomeMaleMiddle AgedOutcome Assessment, Health CareProportional Hazards ModelsProspective StudiesQuality of Health CareSocioeconomic FactorsWhite PeopleConceptsGreater functional declineHeart failureCare indicatorsFunctional declineAfrican AmericansSelf-reported health statusSigns of decompensationDecompensated heart failureHistory of hypertensionProspective cohort studyVentricular ejection fractionDaily living functionAfrican American patientsDaily living functioningRenal insufficiencyBaseline characteristicsCohort studyConsecutive patientsEjection fractionHospital admissionFunctional statusAmerican patientsPoor courseLiving functioningHigh risk
2001
Acute myocardial infarction in the elderly: differences by age
Mehta R, Rathore S, Radford M, Wang Y, Wang Y, Krumholz H. Acute myocardial infarction in the elderly: differences by age. Journal Of The American College Of Cardiology 2001, 38: 736-741. PMID: 11527626, DOI: 10.1016/s0735-1097(01)01432-2.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionAge-associated differencesElderly patientsClinical characteristicsAge groupsMyocardial infarctionThirty-day mortality rateMedicare beneficiaries ageOne-year mortalityPrior coronary diseaseProportion of patientsST-segment elevationOlder age groupsSignificant age-associated differencesChest painEffect of ageOlder patientsRenal insufficiencyCoronary diseaseHeart failureHospital admissionPatient characteristicsSuccessive age groupsSymptom onsetDiabetic patients