2022
Revisiting ACCORD: Should Blood Pressure Targets in People With and Without Type 2 Diabetes Be Different?
Du CX, Huang C, Lu Y, Spatz ES, Lipska KJ, Krumholz HM. Revisiting ACCORD: Should Blood Pressure Targets in People With and Without Type 2 Diabetes Be Different? The American Journal Of Medicine 2022, 136: 6-8. PMID: 35981647, DOI: 10.1016/j.amjmed.2022.07.023.Peer-Reviewed Original Research
2020
Newly diagnosed diabetes and outcomes after acute myocardial infarction in young adults
Ding Q, Spatz ES, Lipska KJ, Lin H, Spertus JA, Dreyer RP, Whittemore R, Funk M, Bueno H, Krumholz HM. Newly diagnosed diabetes and outcomes after acute myocardial infarction in young adults. Heart 2020, 107: 657-666. PMID: 33082173, PMCID: PMC8005796, DOI: 10.1136/heartjnl-2020-317101.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionHealth statusDischarge diagnosisPharmacological treatmentMyocardial infarctionShort-term health statusYoung AMI Patients (VIRGO) studyDisease-specific health statusYoung adultsQuality of lifeHospital complicationsHospital mortalityMedication initiationBaseline characteristicsClinical outcomesDiabetesPatientsDiagnosisPatient studiesMonthsComplicationsInfarctionSignificant differencesOutcomesMortalitySCREENING FOR NEWLY DIAGNOSED DIABETES IN YOUNG ADULTS HOSPITALIZED WITH ACUTE MYOCARDIAL INFARCTION-RESULTS FROM THE VIRGO (VARIATION IN RECOVERY ROLE OF GENDER ON OUTCOMES OF YOUNG ACUTE MYOCARDIAL INFARCTION PATIENTS) STUDY
Ding Q, Spatz E, Lipska K, Lin H, Spertus J, Dreyer R, Whittemore R, Funk M, Bueno H, Krumholz H. SCREENING FOR NEWLY DIAGNOSED DIABETES IN YOUNG ADULTS HOSPITALIZED WITH ACUTE MYOCARDIAL INFARCTION-RESULTS FROM THE VIRGO (VARIATION IN RECOVERY ROLE OF GENDER ON OUTCOMES OF YOUNG ACUTE MYOCARDIAL INFARCTION PATIENTS) STUDY. Journal Of The American College Of Cardiology 2020, 75: 1918. DOI: 10.1016/s0735-1097(20)32545-6.Peer-Reviewed Original Research
2017
Association of the FDA Amendment Act with trial registration, publication, and outcome reporting
Phillips AT, Desai NR, Krumholz HM, Zou CX, Miller JE, Ross JS. Association of the FDA Amendment Act with trial registration, publication, and outcome reporting. Trials 2017, 18: 333. PMID: 28720112, PMCID: PMC5516301, DOI: 10.1186/s13063-017-2068-3.Peer-Reviewed Original ResearchConceptsCardiovascular diseaseTRIAL REGISTRATIONFDA approvalNew drugsClinical trial registrationFDA Amendments ActDrug Administration Amendments ActAccessible trial registryClinical trial publicationsTrials RegistryResultsBetween 2005Efficacy trialsFDA reviewersTrial publicationsOutcome reportingMedical literatureReviewer interpretationsTrialsReporting of findingsDiseaseFDA documentsDrugsDiabetesFDAAAReviewersAdmission Glucose and In-hospital Mortality after Acute Myocardial Infarction in Patients with or without Diabetes: A Cross-sectional Study
Zhao S, Murugiah K, Li N, Li X, Xu ZH, Li J, Cheng C, Mao H, Downing NS, Krumholz HM, Jiang LX. Admission Glucose and In-hospital Mortality after Acute Myocardial Infarction in Patients with or without Diabetes: A Cross-sectional Study. Chinese Medical Journal 2017, 130: 767-775. PMID: 28345539, PMCID: PMC5381309, DOI: 10.4103/0366-6999.202733.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionAbsence of diabetesAdverse clinical eventsAdmission glucoseNondiabetic patientsClinical eventsPrognostic valueBlood glucoseMyocardial infarctionRepresentative sampleGlucose levelsPatientsAdmissionMortalityGlucosePrior studiesHyperglycemiaInfarctionDiabetesMixed resultsStatistical power
2016
Risk-standardized Acute Admission Rates Among Patients With Diabetes and Heart Failure as a Measure of Quality of Accountable Care Organizations
Spatz ES, Lipska KJ, Dai Y, Bao H, Lin Z, Parzynski CS, Altaf FK, Joyce EK, Montague JA, Ross JS, Bernheim SM, Krumholz HM, Drye EE. Risk-standardized Acute Admission Rates Among Patients With Diabetes and Heart Failure as a Measure of Quality of Accountable Care Organizations. Medical Care 2016, 54: 528-537. PMID: 26918404, PMCID: PMC5356461, DOI: 10.1097/mlr.0000000000000518.Peer-Reviewed Original ResearchConceptsHeart failure measuresAccountable care organizationsAcute admission ratesHeart failureAdmission ratesNational ratesUnplanned hospital admissionsHeart failure cohortRisk-adjustment variablesPopulation-based measuresCare organizationsOutcome measure developmentIntraclass correlation coefficientHospital admissionDiabetes measuresFailure cohortChronic conditionsMedicare feeDiabetesService beneficiariesPatientsMeet criteriaMeasures of qualitySocioeconomic statusPerformance categories
2015
National Quality Assessment Evaluating Spironolactone Use During Hospitalization for Acute Myocardial Infarction (AMI) in China: China Patient‐centered Evaluation Assessment of Cardiac Events (PEACE)‐Retrospective AMI Study, 2001, 2006, and 2011
Guan W, Murugiah K, Downing N, Li J, Wang Q, Ross JS, Desai NR, Masoudi FA, Spertus JA, Li X, Krumholz HM, Jiang L, Group T. National Quality Assessment Evaluating Spironolactone Use During Hospitalization for Acute Myocardial Infarction (AMI) in China: China Patient‐centered Evaluation Assessment of Cardiac Events (PEACE)‐Retrospective AMI Study, 2001, 2006, and 2011. Journal Of The American Heart Association 2015, 4: e001718. PMID: 26071031, PMCID: PMC4599529, DOI: 10.1161/jaha.114.001718.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionHeart failureMyocardial infarctionUse of spironolactoneNational practice patternsProportion of patientsAssessment of eligibilitySpironolactone useAldosterone antagonistsSystolic dysfunctionCardiac eventsAMI patientsChina PatientPatient eligibilityPatient groupUnknown indicationPractice patternsIdeal patientPatientsSpironolactoneEligibilityAppropriate useInfarctionDiabetesNational quality assessment
2010
Licensing drugs for diabetes
Lehman R, Yudkin JS, Krumholz H. Licensing drugs for diabetes. The BMJ 2010, 341: c4805. PMID: 20819887, DOI: 10.1136/bmj.c4805.Peer-Reviewed Original Research
2009
Tight control of blood glucose in long standing type 2 diabetes
Lehman R, Krumholz HM. Tight control of blood glucose in long standing type 2 diabetes. The BMJ 2009, 338: b800. PMID: 19264821, DOI: 10.1136/bmj.b800.Peer-Reviewed Original Research
2005
Admission Glucose and Mortality in Elderly Patients Hospitalized With Acute Myocardial Infarction
Kosiborod M, Rathore SS, Inzucchi SE, Masoudi FA, Wang Y, Havranek EP, Krumholz HM. Admission Glucose and Mortality in Elderly Patients Hospitalized With Acute Myocardial Infarction. Circulation 2005, 111: 3078-3086. PMID: 15939812, DOI: 10.1161/circulationaha.104.517839.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionGlucose levelsHigh glucose levelsMyocardial infarctionAdmission glucoseElderly patientsHyperglycemic patientsMortality riskElderly acute myocardial infarction patientsAcute myocardial infarction patientsAdmission glucose levelsMyocardial infarction patientsSimilar glucose levelsGreater mortality riskNondiabetic patientsMultivariable adjustmentDiabetic patientsInfarction patientsElevated glucosePatientsDiabetesGreater riskInfarctionMortality resultsMortality
2001
Baseline Quality Indicator Rates from the National Heart Failure Project: A HCFA Initiative to Improve the Care of Medicare Beneficiaries with Heart Failure
Masoudi F, Ralston D, Wolfe P, Havernek E, Shah V, Krumholz H, Ordin D. Baseline Quality Indicator Rates from the National Heart Failure Project: A HCFA Initiative to Improve the Care of Medicare Beneficiaries with Heart Failure. Congestive Heart Failure 2001, 7: 53-56. PMID: 11828138, DOI: 10.1111/j.1527-5299.2001.990870.x.Peer-Reviewed Original ResearchNational Heart Failure ProjectHeart Failure ProjectQuality indicator ratesHealth Care Financing AdministrationHeart failureMedicare beneficiariesIndicator ratesAcute myocardial infarctionQuality improvement projectPeer review organizationsMyocardial infarctionBreast cancerInpatient feeFailure ProjectCareReview organizationsImprovement projectFailureInfarctionPneumoniaDiabetesStrokeCancerAdministrationQuality indicators
2000
The National Heart Failure Project: A Health Care Financing Administration Initiative to Improve the Care of Medicare Beneficiaries with Heart Failure
Masoudi F, Ordin D, Delaney R, Krumholz H, Havranek E. The National Heart Failure Project: A Health Care Financing Administration Initiative to Improve the Care of Medicare Beneficiaries with Heart Failure. Congestive Heart Failure 2000, 6: 337-339. PMID: 12189341, DOI: 10.1111/j.1527-5299.2000.80175.x.Peer-Reviewed Original ResearchQuality improvement projectHealth Care Financing AdministrationHeart failureMedicare beneficiariesInpatient heart failure careNational Heart Failure ProjectHeart Failure ProjectHeart failure careAcute myocardial infarctionMyocardial infarctionBreast cancerCareImprovement projectFailurePneumoniaInfarctionDiabetesFailure ProjectAdministration initiativesStrokeCancerAdministration