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Peter Peduzzi, PhD

Professor Emeritus of Biostatistics and Senior Research Scientist of Biostatistics

Contact Information

Peter Peduzzi, PhD

Office Location

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Appointments

Biography

Peter is professor of biostatistics at YSPH and director of the Yale Center for Analytical Sciences (YCAS) and the Yale Data Coordinating Center. Dr. Peduzzi has nearly 40 years’ experience in the design, conduct and analysis of clinical trials with a particular focus on pragmatic trials. He is the PI of several data coordinating centers funded by NIH and PCORI. Before coming to Yale he was the Director of the Department of Veterans Affairs (VA) Cooperative Studies Program Coordinating Center in West Haven, Connecticut, which conducts multi-center, multi-national clinical trials and epidemiologic studies. He still maintains an affiliation with this center. His primary research interests have focused on the efficient design and analysis of clinical trials, with a recent focus on clustered randomized trials.

Education & Training

  • PhD
    Yale University (1976)

Activities

  • Antiretrovirals, Options in Management (OPTIMA)
    Canada; United Kingdom 2008
    OPTIMA was a randomized clinical trial coordinated by the VA Cooperative Studies Program Coordinating Center at West Haven, CT, which is a 2x2 factorial trial of salvage therapy evaluating mega-HAART versus standard HARRT and treatment interruption versus no interruption in 368 patients with advanced HIV disease. OPTIMA was a tri-national collaboration among the VA, UK Medical Research Council and the Canadian Institutes for Health Research. The trial was completed in 2008.
  • Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluations (COURAGE)
    Canada (2005-2006)
    COURAGE was a randomized clinical trial coordinated by the VA Cooperative Studies Program Coordinating Center at West Haven, CT, which evaluated maximal medical therapy plus angioplasty versus maximum medical therapy alone in patients with stable coronary disease. The trial enrolled 2287 patients from 50 U.S and Canadian medical centers. The trial was completed in 2006 and published in the New England Journal of Medicine in 2007 (356: 1503-16)

Honors & Recognition

Award
Fellow, Council on Epidemiology, American Heart Association
Fellow, American Statistical Association
Past President, Society for Clinical Trials
VA Research Career Scientist Award
Fellow, Society for Clinical Trials

Departments & Organizations

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