Yale Journal of Biology and Medicine’s December 2022 issue on Antimicrobial Resistance has been published on PubMed Central. This focus issue features articles on the emerging global threat of antimicrobial resistance (AMR): we present articles that discuss the status of AMR and possible therapeutic solutions.
Highlights of the issue include a case report by researchers from Yale’s Department of Ecology and Evolutionary Biology and the Center for Phage Biology & Therapy. Winzig et al. describe the successful use of novel bacteriophages to treat AMR Achromobacter in a patient with cystic fibrosis.
A review by Dessinioti and Katsambas from the University of Athens, Greece, explores antimicrobial resistance in dermatology patients with acne. Cutibacterium acnes plays a key role in the pathogenesis of acne, but misuse of antibiotics has led to resistant strains of the bacterium worldwide.
We also present a review from Mba and Nweze, Department of Microbiology, University of Nigeria, who explore a possible therapeutic solution to AMR called Antimicrobial Peptides (AMP). AMPs are oligopeptides that offer a possible alternative to antibiotics.
Last, we present an important perspectives piece from researchers in the Division of Infectious Diseases, Washington University School of Medicine, St. Louis, MO. Bosserman and Kwon discuss the urgent need for institutional tracking and surveillance of AMR.
Read the entire YJBM archive for free on PubMed Central. The YJBM is open-access for all.
Deputy Editors of this issue: Morgan Vanderwall (Yale University) and Madison S. Strine (Yale School of Medicine).