A digital pathology tool for quantification of color features in histologic specimens
Reschke M, DiRito JR, Stern D, Day W, Plebanek N, Harris M, Hosgood SA, Nicholson ML, Haakinson DJ, Zhang X, Mehal WZ, Ouyang X, Pober JS, Saltzman WM, Tietjen GT. A digital pathology tool for quantification of color features in histologic specimens. Bioengineering & Translational Medicine 2021, 7: e10242. PMID: 35111944, PMCID: PMC8780932, DOI: 10.1002/btm2.10242.Peer-Reviewed Original ResearchTissue samplesColor featuresPathologic featuresDistinct color featuresTissue-based analysisHistologic specimensDigital pathology toolsHistologic samplesExperienced pathologistsImage analysis algorithmsHistologic sectionsPreclinical researchHistological analysisHistological samplesImage analysis toolsCryopreserved tissuesColor thresholdingBetter rigorAnalysis algorithmPathology toolsAnalysis toolsClear needImage assessmentWhole sampleHand tracing