2017
The impact of cumulative pain/stress on neurobehavioral development of preterm infants in the NICU
Cong X, Wu J, Vittner D, Xu W, Hussain N, Galvin S, Fitzsimons M, McGrath J, Henderson W. The impact of cumulative pain/stress on neurobehavioral development of preterm infants in the NICU. Early Human Development 2017, 108: 9-16. PMID: 28343092, PMCID: PMC5444300, DOI: 10.1016/j.earlhumdev.2017.03.003.Peer-Reviewed Original ResearchMeSH KeywordsChild DevelopmentDevelopmental DisabilitiesFemaleHumansInfant, NewbornInfant, PrematureIntensive Care Units, NeonatalMalePainStress, PsychologicalConceptsNeonatal intensive care unitPreterm infantsNeurobehavioral outcomesNeurobehavioral development of preterm infantsOutcomes of preterm infantsDevelopment of preterm infantsSkin-to-skin holdingVulnerable preterm infantsIntensive care unitProspective exploratory studyInfant developmental outcomesNeurodevelopmental outcomesAltered neurodevelopmentNeurobehavioral developmentCare unitNeuroprotective strategiesInfantsAssociated with habituationAcute eventPretermEarly lifeOutcomesNeurodevelopmentDevelopmental outcomesCumulative timeFKBP5 genotype and early life stress exposure predict neurobehavioral outcomes for preterm infants
D'Agata A, Walsh S, Vittner D, Cong X, McGrath J, Young E. FKBP5 genotype and early life stress exposure predict neurobehavioral outcomes for preterm infants. Developmental Psychobiology 2017, 59: 410-418. PMID: 28247564, DOI: 10.1002/dev.21507.Peer-Reviewed Original ResearchConceptsNeonatal intensive care unitNeurobehavioral outcomesNeonatal intensive care unit stressNeonatal intensive care unit careFKBP5 genotypeIntensive care unitEarly life stress exposureStress response-associated genesGenetic susceptibility to stressInfant neurobehavioral developmentPreterm infantsImpact of genetic variationNeurodevelopmental impairmentResponse-associated genesLife stress exposureNeurobehavioral developmentCare unitEnvironmental risk factorsRisk factorsInfant problemsAssociated with neurobehavioral outcomesStatistical analysisPretermSusceptibility to stressStress exposure
2016
Development of Accumulated Pain/Stressor Scale (APSS) in NICUs: A National Survey
Xu W, Walsh S, Cong X. Development of Accumulated Pain/Stressor Scale (APSS) in NICUs: A National Survey. Pain Management Nursing 2016, 17: 354-362. PMID: 27756592, PMCID: PMC5609453, DOI: 10.1016/j.pmn.2016.08.004.Peer-Reviewed Original ResearchMeSH KeywordsFemaleHumansInfant, NewbornIntensive Care Units, NeonatalMalePain MeasurementPsychometricsStress, PsychologicalSurveys and QuestionnairesConceptsNeonatal intensive care unitNeonatal intensive care unit infantsPerception of pain severityHigh-risk neonatesIntensive care unitPain severityInfant neurodevelopmentCare unitInfantsPain/stressAcuityAcuity levelsNeonatal nursesNurses' perceptionsSeverityNeonatesPainNursing membershipNeurodevelopmentProcedureNursesInfant Medical Trauma in the Neonatal Intensive Care Unit (IMTN)
D'Agata A, Young E, Cong X, Grasso D, McGrath J. Infant Medical Trauma in the Neonatal Intensive Care Unit (IMTN). Advances In Neonatal Care 2016, 16: 289-297. PMID: 27391564, DOI: 10.1097/anc.0000000000000309.Peer-Reviewed Original ResearchConceptsNeonatal intensive care unitIntensive care unitMedical traumaCare unitAt-risk infantsLong-term healthUnique stress experienceEarly life adverse experiencesAllostatic loadInfantsLifesaving measuresNICU experienceEmotional outcomesDistressing eventsAdverse experiencesTraumaStressful experiencesPotential outcomesRiskCaregiversEarly developmentNeonates
2015
Early Life Experience and Gut Microbiome
Cong X, Henderson W, Graf J, McGrath J. Early Life Experience and Gut Microbiome. Advances In Neonatal Care 2015, 15: 314-323. PMID: 26240939, PMCID: PMC4583334, DOI: 10.1097/anc.0000000000000191.Peer-Reviewed Original ResearchConceptsGut microbiomeHigh-risk infantsStressful early life experiencesCentral nervous systemSignaling systemPreterm infantsIntestinal innate immunityPain responseBrain-gut-microbiota axisNeonatal careEarly life experiencesNeuroimmune systemMicrobial speciesNervous systemInnate immunityRegulation mechanismInfantsGutMicrobiomeTargeted interventionsRegulationModulating stressPretermState-of-the-science reviewComplex mechanisms
2005
Relaxation and music reduce pain following intestinal surgery
Good M, Anderson G, Ahn S, Cong X, Stanton‐Hicks M. Relaxation and music reduce pain following intestinal surgery. Research In Nursing & Health 2005, 28: 240-251. PMID: 15884029, DOI: 10.1002/nur.20076.Peer-Reviewed Original ResearchConceptsIntervention groupVisual analog scalePost-test painNonpharmacologic nursing interventionsNursing interventionsMultivariate analysis of covarianceAnalysis of covarianceLower painRandomized clinical trialsAmbulancePost-testAnalog scaleInterventionPain reliefPainControl groupMultivariate analysisMusicPain sensationPostoperative reliefClinical trialsPost hoc explorationDistressReliefGroup