2024
98 The Crosstalk between Mitochondrial Dysfunction and Neurodevelopmental Outcomes in Preterm Infants with Pain/Stress in the NICU
Zhao T, Chang X, Biswas S, Balsbaugh J, Liddle J, Chen M, Matson A, Cong X. 98 The Crosstalk between Mitochondrial Dysfunction and Neurodevelopmental Outcomes in Preterm Infants with Pain/Stress in the NICU. Journal Of Clinical And Translational Science 2024, 8: 27-27. PMCID: PMC11023861, DOI: 10.1017/cts.2024.96.Peer-Reviewed Original ResearchNICU Network Neurobehavioral ScalePreterm premature rupture of membranesPost-menstrual agePreterm infantsNeurodevelopmental outcomesNeurobehavioral outcomesAssociated with neurobehavioral outcomesNNNS summary scoresPremature rupture of membranesWeeks post-menstrual ageAssociated with neurodevelopmental outcomesPreterm premature ruptureRupture of membranesAssociated with protein levelsProspective cohort studyMitochondrial dysfunctionNICU hospitalizationNeurobehavioral ScaleClinical characteristicsPretermEpithelial barrierCohort studyReceptor binding activityNICUInfantsPain/Stress, Mitochondrial Dysfunction, and Neurodevelopment in Preterm Infants
Zhao T, Chang X, Biswas S, Balsbaugh J, Liddle J, Chen M, Matson A, Alder N, Cong X. Pain/Stress, Mitochondrial Dysfunction, and Neurodevelopment in Preterm Infants. Developmental Neuroscience 2024, 46: 341-352. PMID: 38286121, PMCID: PMC11284246, DOI: 10.1159/000536509.Peer-Reviewed Original ResearchNeonatal intensive care unitPreterm premature rupture of membranesNICU Network Neurobehavioral ScalePost-menstrual ageNeurodevelopmental outcomesPreterm infantsNeurobehavioral outcomesNeonatal Intensive Care Unit Network Neurobehavioral ScaleNeonatal intensive care unit hospitalizationPremature rupture of membranesWeeks post-menstrual agePreterm premature ruptureRupture of membranesAssociated with neurobehavioral outcomesAssociated with protein levelsAdverse neurodevelopmental outcomesBuccal swabsOptimal neurodevelopmental outcomesProspective cohort studyIntensive care unitEvaluate protein expression levelsNeurobehavioral ScaleClinical characteristicsPretermMitochondrial function-related proteins
2017
FKBP5 genotype and early life stress exposure predict neurobehavioral outcomes for preterm infants
D'Agata A, Walsh S, Vittner D, Cong X, McGrath J, Young E. FKBP5 genotype and early life stress exposure predict neurobehavioral outcomes for preterm infants. Developmental Psychobiology 2017, 59: 410-418. PMID: 28247564, DOI: 10.1002/dev.21507.Peer-Reviewed Original ResearchConceptsNeonatal intensive care unitNeurobehavioral outcomesNeonatal intensive care unit stressNeonatal intensive care unit careFKBP5 genotypeIntensive care unitEarly life stress exposureStress response-associated genesGenetic susceptibility to stressInfant neurobehavioral developmentPreterm infantsImpact of genetic variationNeurodevelopmental impairmentResponse-associated genesLife stress exposureNeurobehavioral developmentCare unitEnvironmental risk factorsRisk factorsInfant problemsAssociated with neurobehavioral outcomesStatistical analysisPretermSusceptibility to stressStress exposure