2020
Is monetary reward processing altered in drug-naïve youth with a behavioral addiction? Findings from internet gaming disorder
Yao YW, Liu L, Worhunsky PD, Lichenstein S, Ma SS, Zhu L, Shi XH, Yang S, Zhang JT, Yip SW. Is monetary reward processing altered in drug-naïve youth with a behavioral addiction? Findings from internet gaming disorder. NeuroImage Clinical 2020, 26: 102202. PMID: 32045732, PMCID: PMC7013339, DOI: 10.1016/j.nicl.2020.102202.Peer-Reviewed Original ResearchConceptsMonetary reward processingInternet gaming disorderReward processingBehavioral addictionsSubstance use disordersNeural responsesGaming disorderMonetary incentive delay taskCurrent fMRI studyDrug-naïve young adultsNon-drug rewardsAltered reward processingIncentive delay taskDrug-naïve youthUse disordersDelay taskProcessing alterationsCaudate activityFMRI studyDrugs of abuseTrait featuresNeural activityNeural featuresOutcome stageSubstance exposure
2017
Reward-related frontostriatal activity and smoking behavior among adolescents in treatment for smoking cessation
Garrison KA, Yip SW, Balodis IM, Carroll KM, Potenza MN, Krishnan-Sarin S. Reward-related frontostriatal activity and smoking behavior among adolescents in treatment for smoking cessation. Drug And Alcohol Dependence 2017, 177: 268-276. PMID: 28651213, PMCID: PMC5564393, DOI: 10.1016/j.drugalcdep.2017.03.035.Peer-Reviewed Original ResearchConceptsAdolescent smokersReward anticipationNeural responsesMonetary incentive delay taskBehavioral Activation ScaleIncentive delay taskNeural reward systemVentral striatal activationCessation treatmentMedial prefrontal cortexBilateral nucleus accumbensNeural correlatesSmoking cessation treatmentActivation ScalesBehavioral inhibitionFrontostriatal responseDelay taskFrontostriatal activityAdolescent nonsmokersStriatal activationPrefrontal cortexEffective smoking cessation interventionsReward systemSmoking cessation interventionTobacco use disorder
2014
Hypoactivation of the Ventral and Dorsal Striatum During Reward and Loss Anticipation in Antipsychotic and Mood Stabilizer-Naive Bipolar Disorder
Yip SW, Worhunsky PD, Rogers RD, Goodwin GM. Hypoactivation of the Ventral and Dorsal Striatum During Reward and Loss Anticipation in Antipsychotic and Mood Stabilizer-Naive Bipolar Disorder. Neuropsychopharmacology 2014, 40: 658-666. PMID: 25139065, PMCID: PMC4289954, DOI: 10.1038/npp.2014.215.Peer-Reviewed Original ResearchConceptsDorsal striatumUnmedicated individualsLoss anticipationPotential ameliorative effectsAddiction-related disordersBipolar disorder IReward processingMonetary incentive delay taskSmall volume correctionFunctional magnetic resonanceIncentive delay taskAntipsychotic medicationVentral striatal activityHealthy comparison individualsPutamen volumeBipolar disorderBD-IIAmeliorative effectMedicated individualsStriatal activityDisorder IStriatumGroup comparisonsNeural activationReward anticipation