2009
Emotional arousal in cocaine exposed toddlers: Prediction of behavior problems
Chaplin TM, Fahy T, Sinha R, Mayes LC. Emotional arousal in cocaine exposed toddlers: Prediction of behavior problems. Neurotoxicology And Teratology 2009, 31: 275-282. PMID: 19465113, PMCID: PMC2743887, DOI: 10.1016/j.ntt.2009.05.002.Peer-Reviewed Original ResearchConceptsEmotional arousalPrenatal cocaine exposureBehavior problemsAge 2 1/2 yearsCocaine exposureAge 5 1/2 yearsAge 2 1/2Subsequent behavior problemsLater psychopathologyEmotional responsesChild behaviorRegulation behaviorsArousalFrustrating taskToddlersTaskYear oldsMore referencesBoysEmotionsComplex relationsPsychopathologyBehaviorYouthFindings
2004
Impaired performance of children exposed in utero to cocaine on a novel test of visuospatial working memory
Schroder MD, Snyder PJ, Sielski I, Mayes L. Impaired performance of children exposed in utero to cocaine on a novel test of visuospatial working memory. Brain And Cognition 2004, 55: 409-412. PMID: 15177825, DOI: 10.1016/j.bandc.2004.02.062.Peer-Reviewed Original ResearchConceptsMaze Learning TestCocaine-exposed groupLearning TestRecall trialsGroton Maze Learning TestVisuospatial working memoryVisuospatial memory functionShort-term memoryInternal spatial mapPrenatal cocaine exposureChase testSignificant group differencesWorking memoryNeuropsychological measuresVisuospatial informationProcedural learningVisuomotor speedLearning trialsImpaired performanceMore errorsMemory functionGroup differencesCocaine exposureMin delayPossible impairment
1999
Developing brain and in utero cocaine exposure: Effects on neural ontogeny
MAYES L. Developing brain and in utero cocaine exposure: Effects on neural ontogeny. Development And Psychopathology 1999, 11: 685-714. PMID: 10624721, DOI: 10.1017/s0954579499002278.Peer-Reviewed Original ResearchConceptsPrenatal cocaine exposureCocaine exposureNeural ontogenyNervous system ontogenyUtero cocaine exposureCNS ontogenyType of exposureMonoaminergic systemsMonoamine systemsPreclinical studiesCocaine effectsNeuropsychological effectsNervous systemPatterns of arousalPrimary siteNeural migrationCell proliferationYoung childrenTrophic roleCocaine-related effectsExposureBrainAttention regulationCandidate mechanismArousal
1998
Regulation of arousal and attention in preschool children exposed to cocaine prenatally.
Mayes L, Grillon C, Granger R, Schottenfeld R. Regulation of arousal and attention in preschool children exposed to cocaine prenatally. Annals Of The New York Academy Of Sciences 1998, 846: 126-43. PMID: 9668402.Peer-Reviewed Original ResearchConceptsPrenatal cocaine exposureArousal regulationRegulation of arousalCocaine exposureAged childrenCocaine-exposed childrenFace of noveltyOngoing information processingSubstance-abusing familiesAttention regulationCocaine-exposed infantsEmotional reactivityImpaired attentionStructured tasksNeurobehavioral findingsStressful situationsInformation processingHuman infantsNeurophysiological findingsPreschool childrenArousalSuch childrenStartle responseStress circuitsNeurobehavioral effectsRegulation of Arousal and Attention in Preschool Children Exposed to Cocaine Prenatally
Mayes L, Grillon C, Granger R, Schottenfeld R. Regulation of Arousal and Attention in Preschool Children Exposed to Cocaine Prenatally. Annals Of The New York Academy Of Sciences 1998, 846: 126-143. PMID: 29087549, DOI: 10.1111/j.1749-6632.1998.tb09731.x.Peer-Reviewed Original ResearchConceptsPrenatal cocaine exposureArousal regulationRegulation of arousalCocaine exposureAged childrenCocaine-exposed childrenFace of noveltyOngoing information processingSubstance-abusing familiesAttention regulationCocaine-exposed infantsEmotional reactivityImpaired attentionStructured tasksNeurobehavioral findingsStressful situationsInformation processingHuman infantsNeurophysiological findingsPreschool childrenArousalSuch childrenStartle responseStress circuitsNeurobehavioral effects
1995
Prenatal cocaine exposure and neurobehavioral development: How subjects lost to follow-up bias study results
Mayes L, Cicchetti D. Prenatal cocaine exposure and neurobehavioral development: How subjects lost to follow-up bias study results. Child Neuropsychology 1995, 1: 128-139. DOI: 10.1080/09297049508402244.Peer-Reviewed Original ResearchNon-exposed infantsCocaine-exposed infantsPrenatal cocaine exposureBiased study resultsCocaine exposureNeurobehavioral developmentBayley ScalesInfantsPsychomotor performanceInfant developmentBias study resultsStatistical significanceStudy resultsBirthMental developmentTotal sampleIndependent groupsBirthweight
1994
Language Abilities of Preschool‐Age Children Living With Cocaine‐Using Mothers
Malakoff M, Mayes L, Schottenfeld R. Language Abilities of Preschool‐Age Children Living With Cocaine‐Using Mothers. American Journal On Addictions 1994, 3: 346-354. DOI: 10.1111/j.1521-0391.1994.tb00251.x.Peer-Reviewed Original ResearchPreschool-age childrenLanguage abilityLanguage delayCocaine-dependent mothersCocaine-dependent womenPrenatal cocaine exposureCocaine-using mothersDrug treatment programsDay care centersLanguage comprehensionLanguage productionCocaine exposureExpressive skillsLanguage impairmentMore impairmentTreatment programSeverity of delayOlder childrenIntervention needsChildrenFuture researchImpairmentSeverityMothersFindings
1992
Prenatal Cocaine Exposure and Young Children's Development
MAYES L. Prenatal Cocaine Exposure and Young Children's Development. The Annals Of The American Academy Of Political And Social Science 1992, 521: 11-27. DOI: 10.1177/0002716292521001002.Peer-Reviewed Original ResearchPrenatal cocaine exposureMaternal cocaine useCocaine exposureCocaine useInadequate prenatal careNeurodevelopmental sequelaeNeurodevelopmental outcomesPrenatal careFetal brainPoor nutritionAvailable findingsMother's capacityExposureChild developmentSequelaeUnique effectsInfantsFactorsGeneral environmental factorsEnvironmental factorsBrainCareThe Problem of Prenatal Cocaine Exposure: A Rush to Judgment
Mayes L, Granger R, Bornstein M, Zuckerman B. The Problem of Prenatal Cocaine Exposure: A Rush to Judgment. JAMA 1992, 267: 406-408. DOI: 10.1001/jama.1992.03480030084043.Peer-Reviewed Original ResearchCocaine exposureCocaine useIntrauterine cocaine exposureCocaine/crack usePrenatal cocaine exposureAdverse developmental outcomesSupportive scientific evidencePattern of cocainePregnant womenCocaine effectsReliable national estimatesNational estimatesCrack useMore womenScientific evidenceDrug epidemicDevelopmental outcomesHigh rateWomenSpecific effectsOutcomesChildrenTrue outcomeExposureNewborns